Some vitamins that should not be taken together, or have dosage limitations, include vitamin C with vitamin B-12, vitamin A supplement with vitamin A-rich foods, folic acid (vitamin B9) and vitamin B12, and vitamin E with vitamin K.
Vitamin C is effectively an acid (it's sometimes known as ascorbic acid), so layering it with AHAs and BHAs like glycolic, salicylic, and lactic acids is a big no-no.
If you supplement vitamin C and B12, you probably do not take them at the same time, as vitamin C may reduce the intake of B12.
Vitamin C supplements can also lead to high aluminum levels if you take them with antacids that contain aluminum. They may also interact with nonsteroidal anti-inflammatory drugs (NSAIDs) and medications that contain estrogen.
Mixing the types of hydroxy acids known as BHA and AHA and vitamin C tends to be too much for the skin, resulting in discomfort or unwanted side effects.
Aluminum-containing antacids -- Vitamin C can increase the amount of aluminum your body absorbs, which could cause the side effects of these medications to be worse. Aluminum-containing antacids include Maalox and Gaviscon. Barbiturates -- Barbiturates may decrease the effects of vitamin C.
Vitamin C + Niacinamide
However, when you combine niacinamide with Vitamin C, they'll cancel each other out chemically, making both formulas ineffective on your skin. Niacinamide takes out all the good properties of Vitamin C and makes it into a substance that can cause redness and trigger breakouts.
Vitamin C and Vitamin D are two essential nutrients that play important roles in the body and help to maintain overall health and wellness. You may be wondering, “Can I take Vitamin D and C together?” The answer is… Yes. In fact, when taken together, they're a powerful combo that can support the immune system.
Vitamin C supplementation is contraindicated in blood disorders like thalassemia, G6PD deficiency, sickle cell disease, and hemochromatosis. Avoid taking supplements immediately before or following angioplasty.
Unlike fat-soluble vitamins, it doesn't require food or specific timing to work effectively. However, some people may want to avoid taking it before bed: If you have acid reflux or a sensitive stomach – Vitamin C, especially in high doses, can increase stomach acidity, and lead to mild heartburn or nausea.
Taking more than 2000 mg daily is possibly unsafe and may cause kidney stones and severe diarrhea. In people who have had a kidney stone, taking amounts greater than 1000 mg daily increases the risk of getting more kidney stones. When applied to the skin: Vitamin C is likely safe for most people.
Vitamin C should not be mixed with acids, which includes all AHAs and BHAs. Vitamin C plays a key role in strengthening the outer layer of our skin barrier, but when combined with an acid, it can enhance the potency of your vitamin C and cause severe irritation [5].
People with malabsorption and certain chronic diseases
Some medical conditions can reduce the absorption of vitamin C and/or increase the amount needed by the body. People with severe intestinal malabsorption or cachexia and some cancer patients might be at increased risk of vitamin C inadequacy [27].
Some medications can cause drug interactions when taken with vitamin D. This can increase your risk of side effects or prevent your body from absorbing vitamin D. Examples of medications that can interact with vitamin D include atorvastatin (Lipitor), orlistat (Xenical, Alli), and hydrochlorothiazide (Microzide).
Iron originating from animal-based sources, called heme iron, and plant sources, called nonheme iron, are absorbed differently. Our bodies tend to not absorb the nonheme iron, or plant-based iron, as easily. It has been found that vitamin C can increase the amount of iron the body absorbs from plant sources.
Combining multiple supplements or taking more than the recommended dose might raise the risk that they can cause harm, said Kitchin. To lower your risk of an overdose, try looking for a multivitamin with no more than 100% of the daily value for any one nutrient to avoid an overdose, said Kitchin.
Possible interactions include: Aluminum. Taking vitamin C can increase your absorption of aluminum from medications containing aluminum, such as phosphate binders. This can be harmful for people with kidney problems.
Anyway, heat and water are the enemies of vitamin C in potatoes, as they are in all vegetables. Vitamin C is soluble in water, and too long an exposure to heat causes nutrients to vanish. Minimise the time, temperature and amount of water.
Space vitamin C and vitamin B12 at least two hours apart—high doses of vitamin C can decrease the absorption and metabolism of vitamin B12. For best absorption, take fat-soluble vitamins (A, D, E, K) with foods containing healthy fats.
We found that a moderate amount of vitamin C can significantly treat and reduce the inflammation, as measured by hs-CRP and IL-6, in hypertensive and/or diabetic adults and also helps to reduce FBG levels.