Retin-A (tretinoin) Cream and Gel and Differin (adapalene) are retinoids (a form of vitamin A) used for the topical treatment of acne vulgaris. Differin is available over-the-counter (OTC).
Though it's not yet understood exactly how these treatments reduce acne symptoms, testing has suggested a fairly simple account of how they differ: adapalene is less likely to cause further irritation, but tretinoin is more potent.
Differin 0.1% Adapalene Gel, for example, can help treat acne. Studies have found evidence to suggest adapalene is just as effective as stronger retinoids, but the skin tends to tolerate it better.
On the whole, studies comparing tretinoin and adapalene typically find that tretinoin is slightly more effective as an acne treatment. In a review of tretinoin and adapalene, researchers found that tretinoin . 05 percent gel “exhibits a greater anti-acne efficacy” than adapalene 0.1 percent gel.
Conclusion: Adapalene 0.3% gel showed non-inferior efficacy to tretinoin 0.05% cream as treatment for photoaged skin, with a similar safety profile. Adapalene 0.3% gel may therefore be considered a safe and effective option for the treatment of mild or moderate photoaging.
In conclusion, tretinoin and adapalene contributed to the wound healing process resulting in an enhancement of collagen production, angiogenesis and granulation tissue formation.
According to Dr. Mohiba Tareen, a board-certified dermatologist, Differin's hero ingredient — adapalene, a type of retinoid — also fights the classic signs of aging: fine lines, dark spots and dull skin.
Adapalene (also known under the brand name Differin) and Tretinoin (also known as retinoic acid) both fight acne, but Tretinoin also treats premature skin aging. Use adapalene if acne is your main problem and you want to experience less irritation.
Absolutely not. It's a common, temporary reaction that will usually subside after about 4 weeks of use. Use of Differin Gel should not be discontinued, but be sure to always use it just once daily. Try a gentle, non-comedogenic moisturizer, like Differin Soothing Moisturizer, to help manage irritation.
Adapalene gel is Food and Drug Administration (FDA) approved for the treatment of acne and has demonstrated clinical lightening of solar lentigines with twice daily application.
As both photodamaged skin and atrophic acne scars share the feature of dermal matrix loss, adapalene 0.3% may potentially exert a beneficial effect in the treatment of atrophic acne scars, similar to its effect on photoaging.
According to Dr. Sheila Krishna, it's totally fine to use vitamin C with over-the-counter retinol products or dermatologist-grade retinoids—which, BTW, is the broader term for vitamin A derivatives, including retinol, tretinoin, and adapalene, just to name a few.
Adapalene. Adapalene is a synthetic retinoid derived from napthoic acid that does not need to be converted to retinoic acid before it becomes active. It's available both over-the-counter and in prescription form, and the few OTC products on the market are all very reasonably priced.
The active ingredient is adapalene, which helps decrease swelling and inflammation, prevent breakouts, and treat scarring. According to Garshick, “it can help discoloration and textural changes that go along with acne scars by evening out the skin tone and boosting collagen production.”
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.
A brief sensation of warmth or stinging may occur right after applying the medication. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use.
Are Retin-A and Differin the Same Thing? Retin-A (tretinoin) Cream and Gel and Differin (adapalene) are retinoids (a form of vitamin A) used for the topical treatment of acne vulgaris. Differin is available over-the-counter (OTC).
Differin is available OTC, classified as a retinoid and is FDA approved for the treatment of acne. In addition to treating acne, retinoids increase collagen production, which reduce fine lines and wrinkles.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
Both retinol and adapalene are retinoids, but only adapalene is FDA-approved to treat acne. Gel) regulate skin cell turnover to keep pores from clogging and to control inflammation.
Additionally, Retin-A comes in a variety of strengths such as 0.25% (the lowest), 0.5% and 1.0 % (the strongest). You'll definitely want to start using the lowest dose once or twice a week.
If you're used to an acid toner, you're going to have to retire it for a while on tretinoin. Either way, apply your toner, then wait for it to dry before applying tretinoin. You can also load your skin up with moisture during this step by using a gentle, hydrating essence.
You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. Check with your doctor if your acne does not improve within 8 to 12 weeks. Do not apply any topical product to the same area where you are using adapalene, unless otherwise directed by your doctor.
Benzac (benzoyl peroxide) is the most effective over-the-counter treatment for mild acne. Treats acne. Differin (adapalene) is commonly used for treating acne, but, it can cause skin irritation. Available over-the-counter from many brands.