BOTOX resistance is a situation in which a patient either has built up antibodies against the botulinum toxin, or happens to metabolize the BOTOX drug exceptionally quickly. As a result, for these patients BOTOX injections provide underwhelming results, a very short-lived effect, or no effect at all.
Immunity to Botox happens when the immune system develops antibodies that neutralize Botox proteins, rendering them ineffective. If you are immune to Botox, the drug will have partial to no paralyzing effect on your treated muscles.
Some of the most common ones involve not getting enough Botox units for your skin issue, Botox not being injected correctly, or it could also be that some wrinkles are at a certain depth and could only be corrected so much.
Thankfully, there are multiple alternatives to Botox you can use if aren't responding. Dysport, Xeomin, Jeuveau are the more common ones. Daxxify is a newer neuromodulator that is supposed to last a bit longer but not widely available at this point.
However, there are certain conditions that may make you ineligible for Botox treatment. These include active infections, acne symptoms, cold sores in the treatment area, muscular or nervous system health issues, allergies to botulinum toxin and pregnancy or breastfeeding.
Not everyone is a good candidate for Botox. If you are in poor general health, your skin is very thick or you have existing muscle weakness in the proposed injection site, you may not be a good candidate for Botox. Patients with sensitive skin may experience an allergic reaction at the injection site.
BOTOX resistance is a situation in which a patient either has built up antibodies against the botulinum toxin, or happens to metabolize the BOTOX drug exceptionally quickly. As a result, for these patients BOTOX injections provide underwhelming results, a very short-lived effect, or no effect at all.
Alternatives to Botox include different types of injectable neurotoxins and fillers, laser resurfacing, and cosmetic surgeries. Diet and a healthy lifestyle can also help reduce the signs of aging.
Daxxify: 5 Things to Know About the New Botox Alternative. In late 2022, the FDA approved Daxxify, a Botox-like injectable for facial wrinkle and line reduction in adult women and men. It is in a family of aesthetic injectables known as neuromodulators, which include Botox, Dysport, Jeuveau, and Xeomin.
"After receiving Botox, a patient may unconsciously attempt to re-create the facial expressions in the area where treatment has paralyzed their facial muscles, "said Dr. Becker. "What can happen is that other, nearby muscles compensate--this can have the effect of actually creating new wrinkles."
Your physical activity level – Proteins needs time to get into the muscles after they are injected. The facial expressions made while working out could make your muscles contract much faster and cause the Botox to wear off.
Other patients are simply fast metabolizers of the product. Several factors can contribute to this including genetics, exercise and stress. While genetics are out of our hands, you can try to improve stress reduction and reduce high intensity workouts to see if this affects your neurotoxin longevity.
This is an effective, well-tolerated treatment6 requiring repeat injections every 6–9 months. However, the failure rate varies from 6% to 32% depending on the studies, and increases over time.
What to do when botox isn't working for your patient anymore. If your patient didn't respond to the toxin, in three months, I would try another brand of botulinum toxin. I would still treat it the same way, just with a different brand of toxin,” Dr Janine explains.
And while the reality star might not have had a rhinoplasty, she admitted to getting “Botox and fillers and lasers and things like that.” In fact, Kris is so fond of injectables that she once told People she was giving friends and family — including her mother, MJ — Botox gift cards for Christmas.
Dysport is best for treating lines on the forehead, glabellar lines (frown lines or the 11s), and crow's feet. Dysport tends to diffuse further than Botox, making it ideal for treating larger areas with wrinkles. It also has a faster onset of results and may last longer in many patients.
Some people show telltale signs of improper Botox injection. They appear as though their natural facial expressions have been inhibited, making them look frozen. A bad Botox job can even cause a person's face to look asymmetrical. Botox, being a powerful chemical, must be administered with utmost caution.
If you have allergies to the ingredients in Botox, if you're pregnant or breastfeeding, or if you have underlying nerve or muscle disorders, you may not be a good candidate for Botox therapy.
When comparing the efficacy of Dysport and Botox, much depends on personal preference. Both have proven effective in diminishing wrinkles and fine lines. Some individuals might appreciate Dysport's swifter action, while others might gravitate towards the precision Botox offers.
A: The cost of Botox for the FDA-recommended dosage of 155 units costs between $300 and $600 for each comprehensive treatment. You would think since the treatment is FDA-approved it should be covered under most insurance plans.
You can also consider treatments such as retinoids, chemical peels, and microneedling. Dermal fillers are another alternative. This injectable treatment typically works immediately and lasts longer than Botox. But it's still a temporary solution.
Yes! Botox is an effective treatment for bruxism that works by freezing the muscles responsible for the tension along the jaw. This freezing of the masseter muscle along the jaw prevents the tension in the facial muscles that is responsible for the pain and damage caused by bruxism.