Why am I gaining weight on Wegovy?

Author: Rashad Funk  |  Last update: Monday, November 17, 2025

Low dosage may also be a reason for weight gain, as some participants taking between 0.25 milligram and 0.5 milligram doses of semaglutide (the generic name for Ozempic and Wegovy) gained weight, according to a New England Journal of Medicine study.

Why is semaglutide making me gain weight?

Semaglutide is not usually known to cause weight gain, although some people may experience some initial bloating during the first few weeks.

Why am I not losing weight in Wegovy?

There could be many reasons why a person is not losing weight while on Wegovy® (semaglutide). Age, amount of regular exercise, dietary habits, and other medical conditions that impact weight can play a role in why someone may not be losing weight on semaglutide or other weight loss medications.

How to break a weight loss plateau on Wegovy?

If you've hit a plateau, try these strategies to break through it:
  1. Reviewing Food. Even on Mounjaro or Wegovy, if you're eating more calories than you burn you won't lose weight. ...
  2. Adjusting Exercise. ...
  3. Get Enough Sleep. ...
  4. Manage Stress. ...
  5. What's Next?

Do you lose more weight with higher doses of Wegovy?

Yes, you are more likely to achieve the maximal weight loss at the highest maintenance dose of Wegovy which is 2.4mg per week. The average Wegovy weight loss of 15% over 68 weeks has only been shown in people who have moved up the dosing schedule and reached the highest maintenance dose.

Why Am I Not Losing Weight on GLP-I Drugs? Wegovy, Zepbound, etc.

Can you gain weight while using Wegovy?

Low dosage may also be a reason for weight gain, as some participants taking between 0.25 milligram and 0.5 milligram doses of semaglutide (the generic name for Ozempic and Wegovy) gained weight, according to a New England Journal of Medicine study.

Why am I not losing weight on semaglutide?

Compounded semaglutide might not help everyone lose weight, and this could be due to several reasons. These can include problems with the dosage, meaning the amount taken might be wrong for some people. Additionally, each person's body reacts differently to medications, affecting how well semaglutide works.

How to speed up weight loss on Wegovy?

5 ways to increase weight loss on Wegovy
  1. Eat a healthy diet. Wegovy helps to reduce appetite and calorie intake. ...
  2. Embrace a physically active lifestyle. ...
  3. Prioritize sleep and stress management. ...
  4. Tailor your dose of Wegovy. ...
  5. Commit to long-term lifestyle changes. ...
  6. The Mayo Clinic Diet can support you.

Does Wegovy cause rebound weight gain?

Wegovy (semaglutide) weight regain

Those who switched to the placebo immediately started regaining weight, while those who stayed on Wegovy continued to lose. Another study looked at patients treated with Wegovy for over a year (68 weeks) and by that point they had lost an average of 17% of their starting weight.

How many weeks is considered a weight loss plateau?

Fluctuations are normal. Water retention, stress, or even a heavy meal can cause your weight to spike temporarily. But if it's been 4 weeks or more and you're seeing zero movement on the scale (even when you're sticking to your plan), that's when you're officially in plateau territory.

How to speed up weight loss on semaglutide?

So now you know what to expect on your semaglutide weight loss journey, here are some handy tips to help you maximize your weight loss results.
  1. Eat little and often. ...
  2. Relish every bite. ...
  3. Make nourishing choices. ...
  4. Drink plenty of water. ...
  5. Lower your alcohol intake. ...
  6. Take it steady. ...
  7. Be active. ...
  8. Rotate injection sites.

What happens if you overeat on Wegovy?

Additionally, you may find it challenging to overeat as this can cause more severe GI-related symptoms such as bloating, cramping, and even vomiting. Wegovy can lead to GI-related side effects due to its impact on the gut.

What is the average weight loss per month with Wegovy?

Combined with diet and exercise, you can expect to lose at least 5% of the initial body weight after the first three months on Wegovy. Remember that weight loss outcomes vary from person to person. On average, people lose around 2% of their body weight with Wegovy in one month.

What happens if you overeat while on semaglutide?

If so, you might wonder, “What happens if I overeat on semaglutide?” Here's the scoop: overeating can often lead to intensified side effects, like nausea, bloating, and even vomiting, which could put a damper on both your day and your weight-loss progress.

Why isn't Wegovy working for me?

About 10% to 15% of people who take Wegovy don't lose weight. But these people may still get other health benefits from taking Wegovy. People who have other medical conditions, including diabetes, may notice less weight loss while taking Wegovy. If you're not losing weight on Wegovy, you may need to take a higher dose.

Why am I suddenly gaining weight on Ozempic?

One possible factor is inadequate dietary control. Even though Ozempic® helps to control overeating by inducing a sense of fullness, if the foods consumed are high in calories, weight gain could still occur. Physical inactivity is another potential contributor.

How did Kelly Clarkson lose weight?

Regular Exercise and Fitness Routines

In addition to her dietary changes, Kelly incorporated regular exercise into her daily routine. Her workout regimen included a mix of cardio, strength training, and flexibility exercises, each of which contributed to her overall fitness and weight loss success.

Does weight loss increase with higher doses of semaglutide?

Weight Loss With Different Semaglutide Doses

At 3 months, patients who received the highest doses achieved a mean (SD) weight loss of 6.9% (3.9%) (95% CI, −7.8% to −6.0% [n = 77]) compared with a mean (SD) weight loss of 5.1% (3.4%) (95% CI −5.8% to −4.4% [n = 98]) for patients receiving lower doses (P = . 002).

How to keep losing weight after Wegovy?

Look for a diet that replaces some of the positive effects of the drugs – such as satiety. What are things in the diet that promote satiety? Well, fiber, protein – there may be other things. There's the other side of the coin, too: I think physical activity is absolutely essential for keeping weight off.

Why can't I lose weight on semaglutide?

A common reason for not losing weight on semaglutide is not being on a high enough dosage. Many patients start on a low dosage and gradually increase it.

How long does it take to lose 20 lbs on Wegovy?

By taking Semaglutide for 4-5 months, you can lose up to 20 pounds. The rate of weight loss depends on various factors, including your metabolism and overall health picture. Again, weight loss treatments such as Wegovy work best when combined with a reduced-calorie diet and increased exercise.

Do some people not lose weight on Wegovy?

Clinical trials have shown that people using weight-loss jabs, such as Wegovy and Mounjaro, lose anywhere between 16% and 21% of their body weight. But the drugs don't work for everyone.

Can semaglutide cause weight gain?

Studies have indicated that with a low dose of semaglutide, 25% of people may gain weight, while people on higher doses of semaglutide see greater weight loss.

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