What should you not layer with hyaluronic acid?

Author: Dr. Montana Wolf DDS  |  Last update: Sunday, April 20, 2025

Niacinamide and Salicylic Acid: Niacinamide is a popular skincare ingredient that can help minimize pores and improve skin texture. Salicylic acid, on the other hand, is often used to treat acne. While both ingredients have their own benefits, using them together with hyaluronic acid may cause irritation or dryness.

What to layer on top of hyaluronic acid?

Hyaluronic acid and Niacinamide are a great pair as both are water-based treatments. When used together, always go with applying hyaluronic acid first, followed by Niacinamide. By following this, you would be able to attract plenty of hydration first.

When should you not use hyaluronic acid?

However, it really shouldn't be used if you live in dry climate with relatively low humidity. Hyaluronic acid pulls moisture from the air or your surroundings into the skin, but if the surrounding are dry it will pull moisture from the deeper layers of you skin, making it dry or drier then it was.

Does hyaluronic acid clash with anything?

Some active ingredients such as retinol and vitamin C can irritate the skin if used in conjunction with exfoliants such as acids, while more gentle humectants such as hyaluronic acid can make a harmonious pairing with just about everything.

Does hyaluronic acid interact with anything?

How does hyaluronic acid interact with other products? Products that combine hyaluronic acid with other medications or compounds may have some risks of side effects. It's important to tell your healthcare provider about all medications that you're taking, including supplements, vitamins, etc.

How I heal my Skin Barrier in 1 WEEK~! my skincare routine for irritated skin 😮‍💨

What you Cannot mix with hyaluronic acid?

However, there are certain ingredients that should not be mixed with hyaluronic acid:
  • AHAs and BHAs: AHAs (alpha hydroxy acids) and BHAs (beta hydroxy acids) are chemical exfoliants that can help improve skin texture and unclog pores. ...
  • Benzoyl Peroxide: Benzoyl peroxide is a common ingredient found in acne treatments.

What is not good with hyaluronic acid?

Things to Avoid With Hyaluronic Acid

While hyaluronic acid is a great hydrator, overusing it can lead to dehydrated skin. This happens because hyaluronic acid can only attract and retain a limited amount of moisture, and using too much can cause it to pull moisture from deeper layers of the skin.

Is there a downside to hyaluronic acid?

The most common adverse effects associated with hyaluronic acid filler are pain, bruising, redness, itching, and swelling. These side effects are self-limited and typically last no more than seven days.

Which serums cannot be used together?

Skincare ingredients not to mix
  • Retinoids or retinol and benzoyl peroxide. ...
  • Retinoids or retinol and vitamin C. ...
  • Retinoids or retinol and salicylic acid. ...
  • Retinoid or retinol and AHAs/BHAs. ...
  • Vitamin C and AHAs/BHAs. ...
  • Vitamin C and benzoyl peroxide. ...
  • Niacinamide and AHAs / BHAs. ...
  • Benzoyl peroxide and hydroquinone.

What is the rule of hyaluronic acid?

The Only Rule for Hyaluronic Acid? Always Apply It on Damp Skin! It might sound surprising, but when hyaluronic acid is applied to dry skin, it can have the opposite effect, leaving your skin even more dehydrated.

Is hyaluronic acid hard on the liver?

10. Is Hyaluronic Acid Bad For Your Liver? In the case of patients with liver diseases, it is advised to avoid using HA as the increased levels of HA in the bloodstream can cause thrombosis. Hence, user discretion and medical supervision are advised.

What happens if you put too much hyaluronic acid on your face?

But like all good things, moderation is crucial. Overloading your skin with HA can lead to the paradoxical drying effect or even irritation. Less is often more. Tune into your skin's needs.

Can I use retinol with hyaluronic acid?

The answer is yes. The combination of these two ingredients can help you treat multiple skin concerns and give you a more youthful, radiant complexion. However, it's important to use these ingredients in moderation and in the correct order to avoid any adverse effects.

What are the side effects of hyaluronic acid serum?

Hyaluronic Acid is generally considered safe, although some people may experience side effects such as swelling, redness, and itching at the injection site. In rare cases, Hyaluronic acid injections can cause an allergic reaction, which can cause severe swelling and difficulty breathing.

Can I layer vitamin C over hyaluronic acid?

Layering vitamin C and hyaluronic acid serums

To layer vitamin C and hyaluronic acid serums, always apply vitamin C first to cleansed, dry skin. Be sure to leave time for your vitamin C to sink in, then follow up with your hyaluronic acid.

What not to layer with Niacinamide?

DON'T MIX: AHA/BHA and niacinamide

Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.

Can I use 3 serums at the same time?

A general rule of thumb is to layer 2-3 serums. This ensures skin doesn't become overwhelmed and gives each formula the space to absorb properly. However – as mentioned above, all skin is unique. Some skin concerns could benefit from up to 5 serums, if heightened moisture, protection and firming for example is needed.

What to avoid when using hyaluronic acid?

3 Hyaluronic Acid Mistakes To Avoid For Happy, Hydrated Skin
  • You're not applying hyaluronic acid to damp skin. It's easy to forget this rule but it's so! ...
  • You're not applying hyaluronic acid in the right order. ...
  • You're not following hyaluronic acid with an oil and/or moisturiser.

What happens if you use hyaluronic acid everyday?

Hyaluronic Acid FAQs. What happens if you use hyaluronic acid every day? Hyaluronic acid may improve the health of your skin, eyes, hair, and joints. Depending on the treatment you're seeking, the form of hyaluronic acid may vary.

What is the best hyaluronic acid for mature skin?

We chose OSEA Hyaluronic Sea Serum as the best for mature skin because of its impressive ability to deliver overnight hydration, leaving our skin looking fresh, plump, and radiant by morning. Mature skin often requires intense moisture to maintain elasticity and minimize fine lines, and this serum excels at both.

What should you not pair hyaluronic acid with?

For instance, Alpha Hydroxy Acids (AHAs), such as Lactic Acid and Glycolic Acid, and Synthetic Retinol are a pair that can easily cause irritation.

Which face serum is best?

  • Vitamin C Daily Glow Face Serum With Vitamin C & Turmeric for Radiant Skin - 30 ml. ...
  • Skin Correct Face Serum with Niacinamide and Ginger Extract for Acne Marks and Scars - 30 ml. ...
  • Vitamin C Daily Glow Face Serum 10 ml. ...
  • Rice Water Dewy Active Serum With Rice Water & 10% Niacinamide For Glass Skin - 50 ml.

Is it better to use hyaluronic acid in the morning or at night?

If you have dehydrated skin, use hyaluronic acid serum both in the morning and at night. In the morning, it might help hydrate your skin and prepare it for the day ahead. At night, it might help repair and rejuvenate your skin while you sleep. Be sure to follow up with a moisturizer to lock in the hydration.

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