What is mistaken as PCOS?

Author: Dr. Barry Rice  |  Last update: Friday, August 22, 2025

Ovarian cysts and PCOS are related conditions with many of the same symptoms, meaning that women often confuse the two, or wrongly believe that they have PCOS when they do not.

What can be misdiagnosed as PCOS?

PCOS can be difficult to diagnose because some of its symptoms have a variety of potential causes. For example, heavy menstrual bleeding could be caused by a range of conditions, such as uterine fibroids, polyps, bleeding disorders, certain medications, or pelvic inflammatory disease, in addition to PCOS.

What else can PCOS be?

PCOS can often be misdiagnosed for something else called Hypothalamic Amenorrhoea. In hypothalamic amenorrhoea (HA), your period can stop due to under-eating and/or overexercising, and similarly to PCOS can present itself with mild acne, excess hair growth and a polycystic ovary appearance on an ultrasound.

How to differentiate between PCOS and Cushing's?

DIFFERENTIAL DIAGNOSIS

Unlike PCOS, Cushing syndrome is associated with the presence of moon facies, a buffalo hump, abdominal striae, and muscle wasting. Given the rarity of this condition, we suggest screening only those who present with these associated symptoms.

What are adrenal PCOS symptoms?

Symptoms of adrenal PCOS
  • Weight gain.
  • Hair loss/growth.
  • Acne.
  • Irregular or missed menstrual cycle.

Misdiagnosed PCOS? Heres 5 Reasons Why

What looks like PCOS but isn't?

Other disorders that mimic the clinical features of PCOS should be excluded: thyroid disease, high prolactin levels, and non-classical congenital adrenal hyperplasia. Large ovaries with many small follicles (which look like cysts, hence the name "polycystic").

What are the symptoms of high cortisol PCOS?

Symptoms of high cortisol levels in women
  • Weight gain. High cortisol can lead to weight gain, especially in the form of belly fat.
  • Problems sleeping. ...
  • Hormonal imbalance. ...
  • Mood swings and depression. ...
  • Reduced immune function. ...
  • Stress. ...
  • Hormonal changes. ...
  • Medication side effects.

What diagnoses are similar to PCOS?

Differential Diagnoses
  • 3-Beta-Hydroxysteroid Dehydrogenase Deficiency.
  • Acromegaly.
  • Adrenocortical (Adrenal Cortical) Carcinoma Imaging.
  • Amenorrhea.
  • Congenital Adrenal Hyperplasia.
  • Gigantism and Acromegaly.
  • Hyperprolactinemia.
  • Hyperthyroidism and Thyrotoxicosis.

What is a PCOS belly?

PCOS belly occurs when you develop excess fat or weight gain around your abdomen. This symptom often occurs due to an underlying diagnosis of polycystic ovary syndrome. Hormonal imbalances and insulin resistance due to PCOS can influence your weight, causing you to gain unwanted weight.

How do I know if I have Cushings adrenal or pituitary?

The first step is to measure ACTH levels in the blood. If ACTH levels are low, the cause is probably an adrenal tumor. People with adrenal tumors don't need further blood tests. If ACTH levels are normal or high, the cause is probably a pituitary or ectopic tumor.

What does a PCOS flare up feel like?

Mood swings: Because of the hormonal imbalance, women with PCOS also have a higher risk for depression, anxiety and extreme or rapid changes in mood. Heavy, painful periods: PCOS can cause painful periods with heavy bleeding. This can cause additional issues, such as anemia, and is often unpleasant and even scary.

What does PCOS discharge look like?

Symptoms: there are no noticeable symptoms in around half of women with the condition, and there is usually no vaginal soreness or itching. Symptoms may include a greyish-white, thin and watery vaginal discharge with a strong fishy smell, especially after sex.

What is the best pill for PCOS?

The easiest way of controlling PCOS is to go on the combined pill (such as Yasmin or Zoely) which prevents recruitment of new egg-follicles and stops the problem from getting worse.

What is the biggest symptom of PCOS?

Irregular periods.

Having few menstrual periods or having periods that aren't regular are common signs of PCOS . So is having periods that last for many days or longer than is typical for a period. For example, you might have fewer than nine periods a year. And those periods may occur more than 35 days apart.

Can hypothyroidism be mistaken for PCOS?

There's some symptom overlap between PCOS and hypothyroidism. Specifically, both conditions can cause fatigue, weight gain, depression, and irregular or heavy menses.

What is the life expectancy of a person with PCOS?

Recent studies have shown that women who were diagnosed as having PCOS 30 years ago have a completely normal life expectancy. An inspection of more than 700 death certificates from women with PCOS has shown that there is no excess risk of cancer in any organ or of heart disease.

What are the four stages of PCOS?

What Are The Four Types of PCOs?
  • Insulin-Resistant PCOS. This is the most common type of PCOS, characterized by insulin resistance. ...
  • Inflammatory PCOS. Low-grade inflammation is a hallmark of this type of PCOS. ...
  • Hidden-Cause PCOS. In this type, the underlying cause of PCOS is not immediately apparent. ...
  • Pill-Induced PCOS.

What is cortisol belly?

Cortisol belly is weight gain in the abdominal area, sometimes referred to as abdominal obesity, caused by an excess of the stress hormone cortisol. It can happen to anyone experiencing prolonged stress. 1. Other factors can also contribute to fat accumulation in the abdomen.

What could mimic PCOS?

Although PCOS is the most prevalent cause of hyperandrogenism, it is important to remember that other diseases can also cause it. Many illnesses, including NCAH, idiopathic hyperandrogenemia (IHA), Cushing's syndrome, acromegaly, adrenal ovarian tumors, and various medicines produce androgen excess.

What is adrenal PCOS?

Adrenal PCOS, as a subtype of Polycystic Ovarian Syndrome (PCOS), is a health condition where the adrenal glands are responsible for the overproduction of androgens. This is unique due to the fact that, in traditional cases of PCOS, excess androgens are typically produced by the ovaries.

What does PCOS get misdiagnosed as?

While thyroid problems can be misdiagnosed as PCOS, it is also possible to experience both hormone issues at the same time. Hashimoto's and hypothyroidism, for example, are more likely to occur for people with PCOS.

What hormone is elevated in PCOS?

Polycystic ovary syndrome (PCOS) is a hormonal imbalance that occurs when your ovaries (the organ that produces and releases eggs) create excess hormones. If you have PCOS, your ovaries produce unusually high levels of hormones called androgens.

What is the best supplement to reduce cortisol?

Omega-3 fatty acids

Omega-3 is especially helpful for your immune system, hormones, heart health, and energy. According to one study, 8 weeks of omega-3 supplementation may reduce morning cortisol levels and symptoms of emotional exhaustion. While fish oil pills often have some omega-3, they may also contain omega-6.

How to balance cortisol PCOS?

Regular Physical Activity: Engaging in regular exercise can reduce stress, improve mood, and support hormonal balance. Adequate Sleep: Prioritize quality sleep, as sleep deprivation can contribute to stress and exacerbate PCOS symptoms.

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