Is niacinamide just as good as vitamin C?

Author: Dr. Melyna Collier DDS  |  Last update: Sunday, July 27, 2025

Key facts: niacinamide vs vitamin C Niacinamide is a gentle, do-it-all ingredient with benefits for all skin types. Vitamin C is a powerful antioxidant with skin brightening and wrinkle-fading effects. Niacinamide is a little milder than vitamin C, but this also depends on the percentage and formula.

What do dermatologists say about niacinamide?

Niacinamide prevents pigment from being transferred to the upper layers of skin where it becomes visible to the naked eye, says Dr. Maarouf. It also minimizes the appearance of pores and redness, leaving your skin as a smooth, even canvas. It regulates oil production.

Is the ordinary vitamin C better than niacinamide?

"Vitamin C is a perfect choice for pigmentation and dull, tired-looking skin. Niacinamide would be a better choice for those [with] acne or spot-prone skin. Niacinamide is also gentler, so if you tend to have sensitive skin, that would be a better choice.

What not to mix with niacinamide?

Niacinamide generally works well with most products, but it's best not to combine it with vitamin C (ascorbic acid) in the same routine as it can cause irritation. Additionally, avoid using it with strong exfoliants or retinoids in high concentrations to prevent skin sensitivity. For more, check out my Quora Profile.

Which is better for skin brightening niacinamide or vitamin C?

Both niacinamide and vitamin C are exceptional skincare ingredients with unique benefits. If you're looking for gentle hydration, oil control, and barrier repair, niacinamide is your best bet. For brightening, anti-ageing, and antioxidant protection, vitamin C is the ideal choice.

Vitamin C Vs Niacinamide | Wrinkles, Dark Spots, Anti-Aging

Do I need vitamin C if I use niacinamide?

Not only should you feel free to combine these two super ingredients, we wholeheartedly encourage it. While there are sometimes tradeoffs in life, luckily this skincare combination isn't one of those times. Layering niacinamide and vitamin C actually enhances the benefits of both these antioxidants.

Is niacinamide or retinol better?

Retinol is usually more effective than niacinamide. The adverse side effects of retinol are not present in niacinamide. From a molecular standpoint, retinol mainly penetrates the skin's outer layer. Niacinamide can permeate the skin more deeply than retinol, mainly when made with soy components.

What reacts badly with niacinamide?

Niacinamide works well with other skincare ingredients, including retinol and hyaluronic acid. However, some ingredients, like vitamin C, may interact negatively with niacinamide. Therefore, it's recommended to use products containing these ingredients at different times of the day or on alternate days.

Is 10% niacinamide too much?

For general skin tone correction, a niacinamide concentration between 4-5% is often effective and well-tolerated by most individuals. For those looking to tackle more pronounced hyperpigmentation, a higher concentration of 10% may be beneficial, though it's important to monitor the skin for any signs of irritation.

What conflicts with niacinamide?

Take for example Vitamin C and Niacinamide - two active ingredients we don't recommend using together in the same routine. The key word here is routine. You can use Niacinamide 10% + Zinc 1% in the AM routine and Ascorbyl Glucoside Solution 12% in the PM routine -- just not together in the morning or evening.

Why is the ordinary niacinamide so good?

Niacinamide helps strengthen the skin's lipid barrier, which is crucial for maintaining moisture and protecting against environmental aggressors. By supporting the skin's natural content of ceramides and fatty acids, niacinamide helps to prevent transepidermal water loss, keeping the skin hydrated and resilient.

What is better than niacinamide?

For those struggling with acne, inflammation, or excess oil production, niacinamide may be the better option. On the other hand, if your primary concern is dryness, dehydration, or aging skin, hyaluronic acid could be the way to go.

Which form of vitamin C is best for skin?

It is important to remember that while derivatives of vitamin C can be absorbed into the skin, they will not always convert into active vitamin C, therefore products that include L-ascorbic acid (pure vitamin C for skin) are preferable.

What are the disadvantages of niacinamide on face?

What are the side effects of Niacinamide? Topical application is completely safe and may not cause any skin problems for a healthy person. People with sensitive skin may face mild redness, itching, or a burning sensation. Stomach upset.

What are the only four skincare ingredients that have been proven to work?

These are retinoids, vitamin C, niacinamide and alpha hydroxy acids (AHAs). Whereas ingredients such as hyaluronic acid temporarily plump and smooth the skin, some of the big 4 may have longer-term health benefits.

Which moisturizer is best after niacinamide serum?

Consider pairing your niacinamide face serum with hyaluronic acid for an enhanced skincare regimen. Combining niacinamide with hyaluronic acid can brighten, hydrate, and plump up your skin. Apply niacinamide serum on a cleansed skin and let it absorb. After a few seconds, follow up with hyaluronic acid face serum.

What should you not mix with niacinamide?

DON'T MIX: AHA/BHA and niacinamide

Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.

Which is better, 5% or 10% niacinamide?

As the percentages suggest, 10% niacinamide contains a higher concentration and strength than 5%. With twice the concentration of their 5% counterparts, 10% niacinamide products offer enhanced delivery of nutrients to skin cells.

Does niacinamide whiten teeth?

【Niacinamide Whitening Toothpaste】Enriched with natural particles and nicotinamide essence, Bodyaccel Niacinamide Whitening Toothpaste quickly eliminates years of coffee, tea, and wine stains for a visibly whiter smile.In addition to whitening, the toothpaste helps to repair and remineralize tooth enamel using calcium ...

What cancels out niacinamide?

Niacinamide and vitamin C

This combination sparks a lot of debate among skincare experts. Some say that since both niacinamide and vitamin C contain antioxidants, they cancel each other out and might even lead to irritation.

Why is my skin getting darker after using niacinamide?

Some may also have skin discoloration due to using niacinamide combined with other active ingredients that are too harsh for your skin type. Niacinamide can also cause problems when it's mixed with the following substances: Acids, including lactic acid, glycolic acid, and azelaic acid.

Which is better for dark spots, niacinamide or vitamin C?

Both ingredients can fade hyperpigmentation and increase collagen production. Vitamin C (depending on the percentage) can be more harsh for sensitive skin types. Or, you might want to use niacinamide if you have acne-prone skin, and leverage Vitamin C for fading post-acne marks and dark spots.

Is niacinamide good for wrinkles?

Results: Analyses of the data revealed a variety of significant skin appearance improvement effects for topical niacinamide: reductions in fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness (yellowing). In addition, elasticity (as measured via cutometry) was improved.

Which is better, tretinoin or niacinamide?

Tretinoin can be quite irritating to the skin, especially when it is first introduced into a skincare routine. Niacinamide's anti-inflammatory properties can help counteract some of this irritation and dryness caused by tretinoin.

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