It might take two or three weeks of using Retin-A (treitinoin) to see any benefits. However, in some cases, it may take six weeks or more.
During the first 3 weeks of using tretinoin, your skin might get irritated, worsening the appearance of your acne, but this should only last a short while. After 12 weeks of continuous use, you should see your acne improve. Rarely does it take more than 12 weeks to show results.
During the first 3 weeks you are using tretinoin, your skin may become irritated. Also, your acne may seem to get worse before it gets better. It may take longer than 12 weeks before you notice full improvement of your acne, even if you use the medicine every day.
The problem with Retin-A is that it may actually make skin look worse — with redness, flakiness and peeling — for up to eight weeks. “But by 24 weeks, patients will see dramatic, marked improvements,” Dr. Lee said. Ms.
Tretinoin degrades quickly when exposed to sunlight, meaning you probably won't get the best results by using it in the morning. Instead, the best time to apply tretinoin is at nighttime — usually 20 to 30 minutes after cleansing your face before you go to bed.
As a result of its effects on your skin's cellular turnover speed, tretinoin reduces the appearance of wrinkles, evens out your skin's pigmentation and also treats skin issues such as acne. The end result is smoother, younger looking skin that's much less affected by fine lines, wrinkles or other common signs of aging.
Generally, it is fine to use tretinoin every night, but you may not want to because of the initial side effects, especially when you first start. You should only use tretinoin as prescribed to avoid significant skin irritation, redness, and other side effects.
Tretinoin Works Best as a Long-Term Treatment
Long-term studies of tretinoin tend to show the most dramatic results, with people experiencing significant reductions in the appearance of fine wrinkling, coarse wrinkling, skin laxity and other signs of photoaging.
Remember, that 'retinoid uglies' are likely to be temporary, and it will take time before you see the end result. You have three skin layers—the epidermis, dermis, and subcutaneous tissue. Your epidermis is your visible layer, and renews approximately every 28 days.
Tretinoin Does Not “Bleach” Your Skin
Contrary to popular belief, tretinoin is not a “bleaching agent” or medicine designed specifically to lighten your skin tone. While tretinoin can even out patches of hyperpigmentation and cause a mild change in your skin tone, it doesn't affect melanin synthesis.
Steps for applying tretinoin
Gently apply to the specific areas on your skin where you need it to work. The medication should fade into your skin right away. If it doesn't, try using a little less the next day. Keep in mind that using a larger amount of tretinoin or using it more often won't make it work faster.
These unwanted effects — particularly skin dryness and acne breakouts — are widely referred to as the “tretinoin purge.” While they don't affect everyone, many tretinoin users experience some degree of purge effects during the first several weeks of treatment.
Tretinoin for acne scars
Tretinoin can also be used to decrease the appearance of acne scarring. Since tretinoin speeds up cell turnover on your skin, it can encourage new cell growth at the site of your scarring. Tretinoin in several forms has been tested successfully as an effective way to treat acne scars.
Tretinoin can help dark spots fade, allowing you to have a more even skin tone. It decreases the amount of melanin in your skin cells (Zasada, 2019). When used for discoloration, tretinoin is usually combined with other skin-lightening products, sometimes in the form of a chemical peel (Lawrence, 2021).
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Avoid using other medications on the areas you treat with tretinoin topical unless your doctor tells you to.
It can take one to two minutes for the tretinoin cream or gel to begin to absorb into your skin, at which point it should no longer be visible. Set a timer for 20 minutes and avoid touching your skin or applying any other skincare products until the tretinoin has been fully absorbed.
Retinoids help mitigate those issues in a variety of ways. They thicken the epidermis through increased cell proliferation at the top level. They increase the production of natural chemicals (such as hyaluronic acid) in your skin that keep it plump and moist.
You might also get more breakouts once you start using retinoids. Keep calm and stick with it. “It's common to see acne get worse before it gets better, as the retinoids can cause a mass 'purge,'” says Robinson. Basically, as skin cell turnover increases, new clogs rise to the top.
While you can't stop the tretinoin process if you want it to work, you can help to make the process less severe. By starting slowly at a low strength or with every-other-day treatment, you can reduce the side effects and the impact on your skin.
But tretinoin, another form of vitamin A, may be the most effective ingredient to firm the skin on your neck and face. Since 1984, multiple studies on animals and people show that tretinoin can firm your skin and increase collagen production to the point where sagging skin becomes less noticeable.
Retin-A achieves a very important goal in anti-aging treatments: it helps boost collagen levels in the skin. Collagen provides skin with firmness and elasticity, but as you age, your cells produce less collagen, allowing wrinkling and sagging to occur.
Does Retin-A (tretinoin) help reverse skin aging? Yes. Retin-A, whose active ingredient is tretinoin, has been shown to have positive effects on both the deeper collagen layers of your skin as well as the upper most layer that is comprised of skin cells.
Yes. It's perfectly safe to use a moisturizer with tretinoin. In fact, tretinoin without moisturizer is generally not recommended. Many dermatologists advise their patients to moisturize while using it to reduce their chance of developing dry, peeling skin.
Do not use this medicine in or around the eyes or lips, or inside of the nose. Spread the medicine away from these areas when applying.
"You can use tretinoin or [over-the-counter] retinols forever."