If the filler is in a location further away from direct blood flow than other locations, then this means that cells that secrete hyaluronidase will not be able to reach the hyaluronic acid gel, and will therefore be unable to dissolve it.
Like most things in life, dermal fillers do not last forever. You can keep your post-filler appearance by sticking to a regular touch-up schedule, but your filler will eventually disappear if left alone.
Answer: DIfferent fillers require different doses of Hyaluronidase. Juvederm and more particalarly juvderm plus require higher doses of hyaluronidase to dissolve compared to other fillers. If the lumps are truly filler it is most likely a dosage issue.
So while the body naturally breaks them down over time, there is a way to speed up the process: Injections of hyaluronidase. Hyaluronidase is what the body produces naturally to break down fillers, so by injecting more, it allows the lips to regain natural shape quicker, usually going down within 3-4 days.
The filler will start to break down and soften immediately, although depending on the location and how much needs to be dissolved, it may take up to two weeks for it to completely dissolve and settle back to natural.
In this case, hyaluronidase could have been an effective treatment if used at the right time, but unfortunately, it was left too late. Nodules can become resistant to hyaluronidase, and in this case, the patient was left with disturbing nodules for 7 years.
Massage can encourage the filler to be broken up by the body more quickly. But in practice this still takes a long time (like weeks of daily vigorous massage) to improve the outcome. This may also spread the product over a larger area causing more problems.
Can all dermal fillers be dissolved? No. Only dermal fillers made from hyaluronic acid can be dissolved with hyaluronidase.
Answer: Filler Can be Dissolved after 1 Year
Yes, your filler can be dissolved if it lasts longer than 1 year, but it needs to be a hyaluronic acid filler. Hyaluronic Acid based filler can be dissolved at anytime with Hyaluronidase.
To dissolve lip fillers, you'll need to receive injections of hyaluronidase (Hyalase) near the filler. Hyaluronidase is a concentrated synthetic form of an enzyme that naturally occurs in your body. When injected, it begins to break down the filler, speeding up the dissolving process that would take place over time.
You can have hyaluronidase as many times as needed. The most I usually do is 3x spread about a week apart.
Slowly inject approximately 0.05ml – 0.1ml per 0.1ml of filler to be dissolved in the centre of the lumps/swelling and then massage gently.
HOW LONG UNTIL I SEE THE EFFECTS OF FILLER DISSOLVING? Hyaluronidase has immediate effect and a half-life of two minutes with duration of action of 24 to 48 hours. Once we start the process of injecting the hyaluronidase, the dermal filler in that area starts to break down and soften immediately.
Fillers are not permanent. How long they last depends on things like the type of filler and where it's injected. They usually last between 6 and 18 months.
In some individuals, they last a bit shorter or longer. Some other fillers such as Sculptra can last 2 years, but usually that is not a first choice for lip augmentation. If you had an HA based filler and want it gone, you can have Hyaluronidase injected to dissolve the filler.
Delayed-onset nodules occur in 0.5% of HA filler treatments, typically four weeks to over one-year post-treatment. These nodules are believed to occur due to either delayed onset inflammation or bacterial biofilms. Often, these nodules have preceding infectious or immune triggers.
Intense heat on the skin can make your filler break down more quickly or produce less effective results. Ideally, you should avoid exposure to intense heat for at least 12 to 24 hours after your appointment.
Conclusions: Our data suggest that the hyaluronidase loses its effect in dermis and subcutaneous tissue within 3-6 hours after the injection and successful engraftment of reinjected HA filler can be accomplished 6 hours after the injection.
You cannot dissolve lip fillers at home. Only licensed medical professionals can administer the enzyme hyaluronidase. However, you can wait for your dermal fillers to dissolve on their own.
Dr. Frank says the best way to deal with migration is to dissolve the filler with hyaluronidase (an enzyme that breaks down hyaluronic acid gels). In just a few hours, hyaluronidase softens the filler and returns the lips to a more natural shape, projection, and size.
Experiencing lumps in lips after injectable filler is extremely common—and lumps most often resolve naturally with time. Gentle lip massage 5-7 days after the treatment can help smooth any lumps and bumps in the lips.
Hyaluronidase works very quickly, with most of the effect taking place within 24 hours. You should be able to see defined improvement and less filler in the area injected, beginning within a few hours. After a few days if you still have areas that need correction, you can see Dr.
Avoid any heat-inducing activities for 24 hours such as strenuous exercise, spas, saunas and hot showers.
A published journal article states that higher doses [of hy'dase] can lead to damage of native extracellular matrix glycosaminoclycans, leaving a gaunt appearance with poor skin texture (Figure 4). Patients are increasingly presenting with hyaluronidase-related damage, which is often untreatable.
This isn't permanent and can be treated with dissolving all of the filler, refilling the lips again subtly after two weeks and in some cases the use of Botox or skin tightening treatments to tighten up the skin around the mouth again and reduce any remaining fine lines.