The most common reason that Botox does not work is that not enough was given. Botox is not a one size fits all treatment and the same dosage does not work for everyone. Some individuals may need additional Botox to reach an effective level of muscle weakness. The Botox may also be old, overdiluted, or fake.
BOTOX resistance is a situation in which a patient either has built up antibodies against the botulinum toxin, or happens to metabolize the BOTOX drug exceptionally quickly. As a result, for these patients BOTOX injections provide underwhelming results, a very short-lived effect, or no effect at all.
To put it plainly, Botox resistance (immunity) does occur in some patients. According to those who do recognize the phenomenon of Botox resistance, the numbers are low—about 1% to 3% of patients who are injected will develop toxin-blocking antibodies.
Many people see absolutely no change at the 2-day mark after BOTOX injections. It usually takes about 7 to 10 days for full results to develop. If you don't see any change by that point, consult your injector, who should be able to give you an explanation and improve your treatment.
The only true way to overcome resistance to botulinum toxin is to wait for the antibodies to disappear from your bloodstream. Unfortunately, this can take 4 to 5 years to happen. In the meantime, your doctor might recommend other treatments that could achieve a similar result.
"Botox binds to receptors on nerve cells to relax muscles, and it is possible that exercise speeds this binding process," Alam explained. "For patients who need quick results, the exercise may be worth the effort.
Answer: Botox takes a while to work
Once the muscles stop contracting, the lines can take quite a while to disappear in some patients. If you continue to maintain the inability of the muscles to contract by having repeat Botox before the muscle wakes up ( around 3 to 4 months), the lines should continue to improve.
The appearance of vertical lines after Botox is due to its unique utilization and weaving. The corrugator muscle is responsible for creating the inter-brow number "11" creases. Once these muscles are crippled, the brain recruits the orbicularis oculi to produce the same expression.
When people see lines forming after BOTOX wears off, they assume treatment made their wrinkles worse. Actually, your face simply returns back to its natural state. No new wrinkles or lines are ever caused by these injections.
Botox® injections work well as a standalone treatment for mild to moderate frown lines. However, if the 11s are deep, Botox® alone may not be enough to reduce the appearance of forehead wrinkles. For the best results with deeper 11s, dermal fillers can be used along with Botox® treatment.
In general, you can see the effects of Botox as early as 3 to 4 days after an injection. Dr. Oscar Trujillo, a facial plastic surgeon at Columbia University Irving Medical Center, says most patients will see results within 10 to 14 days but should wait the full 14 days to see the maximum results.
At what age should you stop using Botox? There is no upper age limit for people who want to have Botox. In fact, many women enjoy the refreshed look they can get from Botox and complementary treatments when they are in their 60s or older.
Why does Botox eventually stop working? Your body makes new neurotransmitters all the time, so the “blocking” effect of Botox gradually wears off as these chemicals start circulating in your body again. The muscles are no longer inhibited.
Some products that may interact with this drug include: certain antibiotics (including aminoglycosides such as gentamicin, polymyxin), anticoagulants (such as warfarin), Alzheimer's disease drugs (such as galantamine, rivastigmine, tacrine), myasthenia gravis drugs (such as ambenonium, pyridostigmine), quinidine.
When someone is receiving too much treatment with anti-wrinkle injections, the skin can become extremely smooth and the light bounces off in a uniform way. So, the skin appears shiny, which is why it can look 'frozen'.
Why Does Botox Make Your Forehead Shiny? Light naturally reflects off of smooth surfaces, so the smoother your skin, the more light will bounce. Botox injections smooth the skin, which can cause it to appear shinier, especially if it is overdone.
It's rare to see cases of Botox being ineffective on the forehead especially if it was administered by a qualified and experienced provider. Despite its high efficacy rate, there are cases when Botox injections on the forehead don't produce the same results clients expect.
25 Units Of Botox On Average
On average 25 units of Botox will give your skin by your glabellar a full correction and will remove the 11 lines. The '11 lines' are the glabellar lines in between your eyes and eyebrows.
BOTOX smooths moderate to severe facial lines and wrinkles, crow's feet, and frown lines. If you have deeper wrinkles or folds, BOTOX injections may soften the look, or you may need to undergo a more comprehensive facial rejuvenation treatment.
In general, you should begin to see results between 24 and 72 hours, but some patients may not see full results for five days or more.
In one to two weeks, you will notice the maximum effect of Botox on even the deepest wrinkles. The good news is: Botox is still working for you! While the short-term effects are excellent, there are still more benefits on the way. Long-term results can occur months after your treatment.
“It's customary to provide an 18 to 20 percent gratuity for any spa service, no matter if it's sugaring or a Biologique Recherche facial,” Angela Rosen, owner of Penelope & The Beauty Bar in Seattle and Daphne in New York City, tells Allure.
It's highly recommended that you move your face around a lot after getting Botox. This includes smiling, frowning, and raising your eyebrows. It's similar to facial exercises, minus the touching. Facial movement may look — and feel — silly, but it actually helps the Botox work better.
Research shows that taking zinc supplements may help extend the results of Botox. In a 2012 study, patients who took a supplement of 50mg zinc and an enzyme known as phytase experienced a 30 percent increase in Botox duration.