If the filler is in a location further away from direct blood flow than other locations, then this means that cells that secrete hyaluronidase will not be able to reach the hyaluronic acid gel, and will therefore be unable to dissolve it.
Answer: DIfferent fillers require different doses of Hyaluronidase. Juvederm and more particalarly juvderm plus require higher doses of hyaluronidase to dissolve compared to other fillers. If the lumps are truly filler it is most likely a dosage issue.
Because dermal fillers are made of hyaluronic acid, a naturally occurring skin compound, they are naturally dissolved by your body over a period of 6 – 18 months. This process uses a compound called hyaluronidase.
So while the body naturally breaks them down over time, there is a way to speed up the process: Injections of hyaluronidase. Hyaluronidase is what the body produces naturally to break down fillers, so by injecting more, it allows the lips to regain natural shape quicker, usually going down within 3-4 days.
The filler will start to break down and soften immediately, although depending on the location and how much needs to be dissolved, it may take up to two weeks for it to completely dissolve and settle back to natural.
Massage can encourage the filler to be broken up by the body more quickly. But in practice this still takes a long time (like weeks of daily vigorous massage) to improve the outcome. This may also spread the product over a larger area causing more problems.
In this case, hyaluronidase could have been an effective treatment if used at the right time, but unfortunately, it was left too late. Nodules can become resistant to hyaluronidase, and in this case, the patient was left with disturbing nodules for 7 years.
Can all fillers be dissolved? Fillers with silicone (which are sometimes used in the lips and face, cannot be dissolved). Other semi-permanent fillers such as Scultpra and Radiesse also can't be dissolved. But temporary fillers, such as Hyaluronic Acid (HA) fillers can easily be dissolved.
Your body naturally dissolves the dermal filler for you over time using a substance called hyaluronidase. This is a naturally occurring material in your body that gradually breaks down the hyaluronic acid in your filler, causing your results to gradually diminish over a period of 6 – 18 months.
Hyaluronic acid dermal fillers such as Juvederm, Restylane, Teosyal and Belotero can be dissolved using an enzyme called Hyaluronidase. This enzyme naturally occurs in our skin but can be injected at higher concentrations in order to rapidly remove unwanted filler.
Can all dermal fillers be dissolved? No. Only dermal fillers made from hyaluronic acid can be dissolved with hyaluronidase.
Dissolving filler is a very simple and quick treatment. It involves no more than 1-4 injections of hyaluronidase into the area that the filler needs to be dissolved, meaning the treatment time takes up to only 10 minutes.
Delayed-onset nodules occur in 0.5% of HA filler treatments, typically four weeks to over one-year post-treatment. These nodules are believed to occur due to either delayed onset inflammation or bacterial biofilms. Often, these nodules have preceding infectious or immune triggers.
You can have hyaluronidase as many times as needed. The most I usually do is 3x spread about a week apart.
Slowly inject approximately 0.05ml – 0.1ml per 0.1ml of filler to be dissolved in the centre of the lumps/swelling and then massage gently.
In order to achieve the most accurate results for reversing the appearance of hyaluronic acid filler, it is best to wait two weeks after your initial treatment to see how the dermal filler settles within the tissue. There can be some swelling as a result of the hyaluronidase injections themselves.
You cannot dissolve lip fillers at home. Only licensed medical professionals can administer the enzyme hyaluronidase. However, you can wait for your dermal fillers to dissolve on their own.
A published journal article states that higher doses [of hy'dase] can lead to damage of native extracellular matrix glycosaminoclycans, leaving a gaunt appearance with poor skin texture (Figure 4). Patients are increasingly presenting with hyaluronidase-related damage, which is often untreatable.
The price range varies depending on your provider and how many sessions you need but you can expect to pay somewhere around $500 for your filler removal.
Avoid any heat-inducing activities for 24 hours such as strenuous exercise, spas, saunas and hot showers.
HOW LONG UNTIL I SEE THE EFFECTS OF FILLER DISSOLVING? Hyaluronidase has immediate effect and a half-life of two minutes with duration of action of 24 to 48 hours. Once we start the process of injecting the hyaluronidase, the dermal filler in that area starts to break down and soften immediately.
Hyaluronidase works very quickly, with most of the effect taking place within 24 hours. You should be able to see defined improvement and less filler in the area injected, beginning within a few hours. After a few days if you still have areas that need correction, you can see Dr.
Intense heat on the skin can make your filler break down more quickly or produce less effective results. Ideally, you should avoid exposure to intense heat for at least 12 to 24 hours after your appointment.
Experiencing lumps in lips after injectable filler is extremely common—and lumps most often resolve naturally with time. Gentle lip massage 5-7 days after the treatment can help smooth any lumps and bumps in the lips.