Hydroquinone. Topical HQ is regarded as the gold standard for the treatment of facial hyperpigmentation. HQ is a bleaching agent that acts by inhibiting tyrosinase to limit melanin production in the skin.
Ask a Dermatologist About High-Tech Options
“I treat hyperpigmentation regularly using a combined approach of topical treatments and procedures,” Dr. Vashi says. “Procedures include chemical peels with alpha and beta hydroxy acids, microneedling, and certain types of lasers.”
Areas of hyperpigmentation might also fade on their own without treatment. To help speed up the process, there are several different types of topical medication that can reduce PIH skin spots: Skin lighteners such as hydroquinone and azelaic acid to help reduce melanin production.
According to research, aloe vera includes aloin, a naturally occurring depigmenting substance that has been demonstrated to lighten skin and function well as a nontoxic hyperpigmentation therapy. For using this: Before going to bed, apply pure aloe vera gel on pigmented areas. The next morning, rinse with warm water.
Try: A skin-lightening ingredient like hydroquinone or cysteamine hydrochloride. Hydroquinone has been used for decades to help lighten dark spots. It's recommended for those who have stubborn melasma—you probably don't need hydroquinone if you have mild hyperpigmentation, says Dr.
How long does it take for hyperpigmentation to fade? Once what's causing the dark spots or patches is found and stopped, fading can take time. A spot that is a few shades darker than your natural skin color will usually fade within 6 to 12 months. If the color lies deep in your skin, however, fading can take years.
Vitamin C Serum
Vitamin C is known to reduce production of melanin and thus helps to lessen hyperpigmentation. Applying a vitamin C-containing serum or using citrus juice like lemon or orange juice can thus help lighten dark spots.
Retinoids are useful in the treatment of hyperpigmentation because they reduce epidermal melanin by blocking the transcription of tyrosinase, induce desquamation, disperse keratinocyte pigment granules and enhance epidermal cell turnover via epidermopoiesis.
Topical therapies (creams and lotions applied to the skin) are the most common treatment option for hyperpigmentation. Combination therapy, in which multiple topical treatments are used together, is usually most effective in treating hyperpigmentation. The most common cause of hyperpigmentation is sun exposure.
Tranexamic acid has also found to inhibit tyrosinase activity to reduce hyperpigmentation. Tyrosinase is an enzyme that catalyzes the first step of melanin synthesis from the protein tyrosine. This mechanism of action of tranexamic acid leads to a slowed melanin synthesis and lightened hyperpigmentation.
Lactic acid treats acne, acne scarring, dark spots, hyperpigmentation, photoaging, and other skin blemishes.
CO2 Laser Resurfacing is the most effective non-surgical method to improve the appearance of your skin overall and hyperpigmentation specifically. It uses highly specialized lasers to remove dead and damaged skin cells and stimulate collagen production.
Hydroquinone. Topical HQ is regarded as the gold standard for the treatment of facial hyperpigmentation. HQ is a bleaching agent that acts by inhibiting tyrosinase to limit melanin production in the skin.
One question customers have asked us time and time again is, "do any dark spot correctors work?" The answer: Yes—but it takes time (so patience is a must). To notice real results, you'll also want to build a complete skincare routine around addressing skin discolorations.
Vitamin C can help reduce hyperpigmentation and even out skin tone, with noticeable results in as little as 3-4 weeks.
Three of the best vitamins for lightening dark spots are vitamin C, vitamin B12, and vitamin E. Vitamin C helps your skin produce more collagen while inhibiting the formation of melanin. Vitamin B12 also promotes collagen formation while supporting the growth of new skin cells.
Some of the best creams for pigmentation in India include Kojic Acid and Vitamin C Cream (₹95) and Zeeglow Glycolic Acid, Arbutin, and Kojic Acid Cream (₹149). These creams are effective in reducing dark spots and evening out skin tone.