(HY-poh-trih-KOH-sis) A rare condition in which there is little or no hair growth on the head, including the brows above the eyes and the edge of the eyelids, or other areas of the body where hair normally grows.
Hypotrichosis, defined, is a medical term used to describe a condition in which natural hair growth does not occur. Commonly affecting people at birth, the condition will remain throughout the entire life of an affected individual. This condition is often confused with alopecia.
Most forms of hypotrichosis have no treatment. An exception involving hypotrichosis of the eyelashes exist, a medication called Latisse, the brand name for bimatoprost.
Alopecia is the absence of hair; hypotrichosis, which is much more common, is the presence of less hair than normal. Although these defects can be generalized, they commonly develop in patterns that spare extremities or correlate with hair color.
corticosteroids - facial hypertrichosis may result from prolonged or intensive therapy. penicillamine - associated with hypertrichosis affecting the trunk and limbs. psoralens - may induce temporary hypertrichosis on light-exposed areas. diazoxide - hypertrichosis occurs in 50-100% of children treated.
First signs and symptoms may be apparent at birth. Bony involvement is progressive, with more than 84% of adults requiring ambulation aids; life span does not appear to be limited.
Bimatoprost is an ophthalmic prostamide analog that is approved by the United States Food and Drug Administration for the treatment of eyelash hypotrichosis.
About Hypotrichosis simplex
Many rare diseases have limited information. Currently, GARD aims to provide the following information for this disease: Population Estimate:Fewer than 1,000 people in the U.S. have thisdisease. Symptoms:May start to appear as a Child.
Hypotrichosis simplex is an autosomal dominant condition characterized by a hair defect confined to the scalp, with no other ectodermal or systemic abnormalities. Hair may be normal at birth with gradual progressive thinning of scalp hair with age.
Congenital atrichia is the total absence of hair from birth, usually an inherited condition. It may occur as isolated[1] or associated with other anomalies[2]. Congenital atrichia may be associated with papular lesions on the face, neck, trunk, or limbs[3] that may not be present at birth and may occur later in life.
Autosomal recessive hypotrichosis can be caused by mutations in the LIPH, LPAR6, or DSG4 gene. These genes provide instructions for making proteins that are involved in the growth and division (proliferation) and maturation (differentiation) of cells within hair follicles.
Hypotrichosis is a term dermatologists use to describe a condition of no hair growth. Unlike alopecia, which describes hair loss where there was formerly hair growth, hypotrichosis describes a situation where there wasn't any hair growth in the first place.
Hypotrichosis is characterized by a less than normal amount of hair, and eyelashes hypotrichosis is the term for an inadequate amount of eyelashes.
There is no specific treatment for hypotrichosis simplex, counseling is the mainstay of management (8). However, few trials have been demonstrated in literature (6,9). Minoxidil was used with improvement of a case of congenital hypotrichosis due to autosomal recessive wooly hair.
Zinc and Hair Health: Zinc is essential for keratin production, hair growth cycles, and follicle integrity. Supplements have shown promising results for addressing hair loss and related issues. Zinc Deficiency Symptoms: Zinc deficiency can lead to hair shedding, brittleness, and scalp issues.
Hair loss (alopecia) can affect just your scalp or your entire body, and it can be temporary or permanent.
People with this condition have sparse hair (hypotrichosis) on the scalp beginning in infancy. This hair is usually coarse, dry, and tightly curled (often described as woolly hair). Scalp hair may also be lighter in color than expected and is fragile and easily broken.
It can indicate poor nutrition and malnourishment. Healthcare providers believe lanugo grows when a person doesn't have enough body fat to keep them warm. In response, their body grows lanugo to help insulate the body.
This is normal. You might also notice that your little one is a bit furry. This hair, called lanugo, typically falls off in the womb in the last few weeks of pregnancy, but preterm babies often don't have a chance to shed it before birth. Not to worry, it will eventually come off on its own.
Keratoderma with woolly hair is a group of related conditions that affect the skin and hair and in many cases increase the risk of potentially life-threatening heart problems. People with these conditions have hair that is unusually coarse, dry, fine, and tightly curled. In some cases, the hair is also sparse.
Eyebrow hypotrichosis, also known as madarosis, is characterized by a lack of growth or loss of eyebrow hair. Eyebrow loss can have cosmetic, functional, and social consequences.
Alopecia universalis
This is the most advanced (and rarest) form of alopecia areata. Alopecia universalis causes all of the hair on your body to fall out—including your eyebrows and eyelashes.
Oral Finasteride
Finasteride slows the rate of hair loss and stimulates new hair growth by inhibiting the body's production of a hormone that destroys hair follicles. This medication is taken once a day by mouth and is most effective when taken at the same time each day.
Ritlecitinib (LITFULO) is a new medication, developed by Pfizer, that is effective at treating severe alopecia areata cases. This medicine is usually taken in tablet form and inhibits the Janus kinase 3 (JAK3) and tyrosine kinase receptors that have been linked with alopecia areata-related hair loss.