What happens if I put too much tretinoin on my face?

Author: Prof. Miller Corkery IV  |  Last update: Sunday, September 14, 2025

Applying excessive amounts of tretinoin onto the skin to make acne go away faster will not work. This can make the skin worse by causing extreme dryness, peeling, or redness. It may take up to six weeks of tretinoin treatment to see results. Make sure to use sunscreen, especially in the summertime.

What does overuse of tretinoin look like?

Symptoms of overdose with topical tretinoin use may include excessive redness, peeling, and discomfort. Symptoms of overdose with oral tretinoin include the following: cracked and sore lips, redness, headache, flushing, stomach pain, dizziness, loss of coordination.

What happens if tretinoin is too strong?

However, with increased strength comes a greater likelihood of side effects. These include purging, redness, peeling, post inflammatory hyperpigmentation and dryness. This is why it is crucial to approach higher concentrations with caution. For this reason, Tretinoin is a prescription only medicine.

How long does tretinoin burn last?

Retinol burns heal on their own over 1 to 2 weeks, typically. But Dr. Robinson cautioned, “For people with sensitive skin or underlying conditions, like eczema, it may take a little longer.” If you develop a retinol burn, stop using retinol products until your skin heals.

What does tretinoin purge look like?

Skin purging is common, but doesn't necessarily happen to everyone. In fact some people don't experience it at all. For those of us who do suffer from purging, it can look like: breaking out in pustules (pimples), the appearance of flaky, peeling skin, irritation and dry patches.

Not Seeing Results with Retin-A (TRETINOIN)? Watch This Before You Quit & Avoid My Biggest Mistake

What does a retinol burn look like?

The skin goes red, inflamed, and peeling because retinol has chemically burned away the upper layer of skin, the new exposed skin has not had enough time to build up its natural protection film to UV light and pollutants that a good UV moisturising oil can help with and reduce the exposure to skin cancer risk, ...

Can I put vaseline over tretinoin?

Generally speaking, let tretinoin absorb and fully dry before applying moisturizer.

Is tretinoin ruining my skin?

The skin will be more prone to sunburn, dryness, or irritation, especially during the first 2 or 3 weeks. However, you should not stop using this medicine unless the skin irritation becomes too severe.

Am I applying too much tretinoin?

You should also avoid using too much of your tretinoin cream. You only need a pea-sized amount to cover your entire face. Using too much cream can increase your risk of experiencing side effects without offering extra benefits.

Is tretinoin 0.05 or 0.025 better?

In general a lower tretinoin strength (0.025%) may be used for mild to moderate acne, while higher strengths (0.05% or 0.1%) may be used for more severe or stubborn acne,” says Dr. Anna Chacon, dermatologist.

What face moisturizer is best with tretinoin?

Three inexpensive moisturizers that our physicians love are Vanicream Daily Facial Lotion with Hyaluronic Acid, Neutrogena Hydroboost Gel, and The Ordinary Hyaluronic Acid Serum. All three of these are affordable, non-comedogenic,and blend well with tretinoin.

How do you recover from tretinoin damage?

How to Treat Peeling Skin from Tretinoin
  1. Look at your face wash. ...
  2. Choose a fragrance-free, hypoallergenic moisturizer made for sensitive skin. ...
  3. You will also need to choose a product that provides sun protection since topical retinoids can make your skin more susceptible to sun damage.

What are tretinoin uglies?

A tretinoin purge, also referred to as “tretinoin uglies” is a common skin reaction that occurs when a patient uses tretinoin (Retin-A or Tretin-X) for the first time.

How to know if tretinoin is working?

After 4-6 weeks, your skin will get used to Tretinoin and will begin to be noticeably smoother and more even. Depending on how often you use Tretinoin, you may begin to see full benefits by this point. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.

What is the downside of tretinoin?

Topical tretinoin can cause your skin to become dry, red, swollen, blistered, or flaky. It may also cause your skin to itch, be painful, or feel like it is burning. Stop using topical tretinoin and call your healthcare provider if these symptoms become worse or do not go away.

Does moisturizer ruin tretinoin?

Apply a base layer of your favourite moisturizer, then apply tretinoin. Studies have shown that the base layer does not dilute or reduce the efficacy of the retinoid, in fact it helps with tolerability. Look for ingredients such as glycerin, hyaluronic acid or squalene as a key moisturizing ingredient.

Is tretinoin 3 times a week enough?

Conclusion: After 48 weeks of once-daily treatment, the continued use of tretinoin emollient cream 0.05% at a dose of three times per week maintains and, in some cases, may further enhance improvement in photodamage.

How to sludge your face?

Slugging step-by-step guide
  1. Prep your skin. “Slugging should only be done on clean skin, so start your evening routine with cleansing, exfoliating and moisturizing,” Dr. ...
  2. Apply a small amount of petroleum jelly. ...
  3. Wait 30 minutes before bed. ...
  4. Sleep on it. ...
  5. In the morning, wash your face.

What is the sandwich method of tretinoin?

Option one: The sandwich technique

After washing your face, apply a layer of moisturiser. Allow it to dry down for 5-10 minutes. Then, apply a pea-sized amount of tretinoin to your entire face. Allow this to dry down for 5-10 minutes.

Does tretinoin peeling ever stop?

Tretinoin skin peeling is usually temporary and only lasts for a few months for most people, meaning patience is normally an effective approach. Use a moisturizer. It's totally okay to use a moisturizer with tretinoin. Apply the moisturizer first before tretinoin if you have skin dryness.

How long do retinol uglies last?

The retinol uglies can last anywhere from 4–8 weeks. The exact length of a retinoid purge depends very much on your skin type and sensitivity. The amount and strength of your retinoid product can also play a part. Some people experience a purge flare-up for only a few days, and others don't get it at all.

Is topical tretinoin bad for the liver?

Retinoids have been implicated in causing mild-to-moderate elevations in routine liver tests, but these elevations are usually asymptomatic and transient, resolving spontaneously even with continued therapy.

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