The answer is C: argyria. Argyria is a rare skin condition associated with chronic exposure to products containing silver. The silver is typically deposited diffusely in skin, fingernails, oral mucosa, and conjunctival membranes.
Blue or grey skin or lips (cyanosis) happens when there's not enough oxygen in your blood, or you have poor blood circulation. It can be caused by a serious problem with the: lungs, like asthma or pneumonia.
Melasma: Brown or gray patches of skin caused by hormonal changes (like pregnancy) or medications. It's typically found on your face. It usually fades over time, but some people use topical lightening creams or seek laser treatment from a healthcare provider.
Vitiligo is a chronic (long-lasting) autoimmune disorder that causes patches of skin to lose pigment or color. This happens when melanocytes – skin cells that make pigment – are attacked and destroyed, causing the skin to turn a milky-white color.
Pigmented basal cell cancers have dark areas, often brown, blue or grey in colour.
According to the American Academy of Dermatology (AAD), the skin in people with kidney failure may become: pale. gray.
The hyperpigmentation related to vitamin B12 deficiency is more common in darker-skinned patients. Few other cases of skin hyperpigmentation due to vitamin B12 deficiency have been reported in the literature. The mechanism of hyperpigmentation is due to increased melanin synthesis rather than a defect in melanin.
Localized scleroderma typically causes patches of thick, hard skin in one of two patterns. Morphea causes patches of skin to thicken into firm, oval-shaped areas. These areas may have a yellow, waxy appearance surrounded by a reddish or bruise-like edge.
Acquired diseases with gray coloring include late-stage organ failure, lichen planus pigmentosus, erythema dyschromicum perstans, and drug reactions. The discoloration is due to either increased epidermal and or dermal melanin or dermal deposition of a chromogen or a combination of both.
Paleness may be the result of decreased blood supply to the skin. It can also be due to decreased number of red blood cells (anemia). Paleness of the skin is not the same as loss of pigment from the skin. Paleness is related to blood flow in the skin rather than deposit of melanin in the skin.
Argyria is a rare condition that causes the skin to turn a blue or gray color.
Call your health care provider for an appointment if you have: Skin discoloration that causes significant concern. Persistent, unexplained darkening or lightening of the skin. Any skin sore or lesion that changes shape, size, or color may be a sign of skin cancer.
Your hair follicles produce less color as they age, so when hair goes through its natural cycle of dying and being regenerated, it's more likely to grow in as gray beginning after age 35. Genetics can play a role in when this starts.
The deficiency of vitamin B12 can cause specific skin manifestations, such as hyperpigmentation, vitiligo, angular stomatitis, and hair and nail changes [1].
Any deficiencies of vitamin B9, B12, biotin, or vitamin D can contribute to premature graying. One 2018 review notes various deficiency studies on vitamin D3, vitamin B12, copper, zinc, and calcium and their connection to graying hair.
Duke dermatologists diagnose autoimmune skin diseases like pemphigus, pemphigoid, scleroderma, morphea, dermatomyositis, dermatitis herpetiformis, vasculitis, lupus, and Sjögren's syndrome -- all of which occur when the body's immune system attacks healthy skin or tissue.
Gay Saget died from scleroderma, an autoimmune disease where excess collagen causes tissue to lose its elasticity, in 1994. She was 47.
The allergy can be triggered by taking vitamin B12 supplements because B12 contains cobalt atoms. Cobalt allergies most often develop in people exposed to it in eye makeup, tattoos, or industrial products, causing an itchy, red, scaly rash.
Vitiligo (vit-ih-LIE-go) is a disease that causes loss of skin color in patches. The discolored areas usually get bigger with time.
Many people with chronic lymphocytic leukaemia (CLL) won't have any symptoms at all. They are diagnosed because they have a routine blood test for something else. In CLL, symptoms tend to be mild at first and get worse slowly. Many symptoms are vague. You may feel as if you had the flu.