What Cannot be combined with tranexamic acid?

Author: Mrs. Aaliyah Bogan DVM  |  Last update: Thursday, March 27, 2025

Tranexamic acid can be taken with most other medicines. However, talk to your doctor or pharmacist if you're taking the combined contraceptive pill. There could be a very small increased risk of getting a blood clot if you take tranexamic acid as well.

What not to mix tranexamic acid with?

Tranexamic Acid Serum can be used with all products in our range however we'd recommend not to use alongside a moisturizer / oil as it is unlikely to layer well.

What can you not take with tranexamic acid?

Your pharmacist can tell you all of the ingredients in the specific tranexamic acid products they stock. Birth Control. Do not take tranexamic acid if you are using birth control that contains both estrogen and a progestin (combined hormonal contraceptive).

When should you avoid tranexamic acid?

have ever had an allergic reaction to tranexamic acid or any other medicine. have ever had a blood clot in a vein (deep vein thrombosis) or in your lungs (pulmonary embolism) have had a coagulopathy – a rare condition where lots of small blood clots form in your blood followed by abnormal bleeding. have epilepsy.

What can tranexamic acid serum be mixed with?

Combining it with retinol or kojic acid or vitamin c, or niacinamide is a great idea as the skin brightening effect of tranexamic acid only gets further enhanced. It can be used at any hour of the day but only at night when used with retinoids.

Skincare Ingredients You CAN'T Mix?! | Doctorly Investigates

What works well with tranexamic acid?

Complementary Products: You can use tranexamic acid alongside other active ingredients like niacinamide, hyaluronic acid, and Vitamin C. These combinations can enhance the overall effectiveness of your skincare routine.

What acids should not be used together?

Glycolic acid and salicylic acid are great ingredients used separately (or in pre-formulated blends) but mixing the two yourself could cause a major reaction and compromise your skin barrier. One word: ouch.

What is the disadvantage of tranexamic acid?

This medicine may increase your or your child's risk of developing blood clots. Check with your doctor right away if you or your child have swelling and pain in your arms, legs, or stomach, chest pain, trouble breathing, loss of sensation, confusion, or problems with muscle control or speech.

Can you use tranexamic acid and vitamin C at the same time?

The good news is that topical tranexamic plays nice with vitamin C, so in most cases it's totally safe to use the two together. In fact, doubling up on brighteners may help fade your dark spots and hyperpigmentation even fast.

What is a natural alternative to tranexamic acid?

Additionally, a systematic review of three clinical trials found that ginger capsules and myrtle fruit syrup significantly reduced menstrual duration and blood loss compared to a placebo 4. Pomegranate flower capsules were also as good as tranexamic acid at reducing blood loss 4.

What happens to period blood when you take tranexamic acid?

Tranexamic acid is used to treat heavy menstrual bleeding in women. This medicine may be used by teenage females, but is not intended for use before the start of menstruation. Tranexamic acid is an antifibrinolytic agent. It works by blocking the breakdown of blood clots, which prevents bleeding.

Can you take vitamin D with tranexamic acid?

Interactions between your drugs

No interactions were found between tranexamic acid and Vitamin D3. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Is tranexamic acid a high risk medication?

Tranexamic acid injections have been added to the Institute for Safe Medication Practices' (ISMP's) 2024 List of High-Alert Medications in Acute Care Settings. “High-alert” medications have an increased risk of causing significant harm to patients when they are incorrectly administered.

Does tranexamic acid cause weight gain?

It's effects are reversible. Possible unwanted side effects: Many women stop having periods when taking this drug. Common unwanted effects include stomach pain, feeling sick, headaches, dizziness, tiredness, weight gain, hot flushes and breast tenderness. What is it?

Can I mix retinol and tranexamic acid together?

Can tranexamic acid be used with retinol? Yes, formulas containing tranexamic acid can be used with retinol. It is recommended that tranexamic acid formulas for the skin be applied before retinol.

How quickly does tranexamic acid work?

It can take up to 24 hours for the medicine to take full effect.

What to avoid with tranexamic acid?

Cautions with other medicines

Tranexamic acid can be taken with most other medicines. However, talk to your doctor or pharmacist if you're taking the combined contraceptive pill. There could be a very small increased risk of getting a blood clot if you take tranexamic acid as well.

What is a good combination with tranexamic acid?

Niacinamide, Vitamin C, and hyaluronic acid are excellent companions, as they further enhance skin brightening, hydration, and overall skin health. However, it is crucial to ensure that these combinations are stable and do not cause any adverse reactions.

Can tranexamic acid damage kidneys?

With its antifibrinolytic properties, tranexamic acid may harm the kidneys by favoring the formation of blood clots affecting kidney vessels and causing cortical necrosis.

What is the success rate of tranexamic acid?

The Evidence: Tranexamic Acid and HMB

Tranexamic acid reduced the amount of blood loss by 40% to 50% for each menstrual cycle [19], translating to an average reduction of 80.32 mL/cycle (95% CI, 32.98-127.67 mL) [5].

Can you use vitamin C and tranexamic acid together?

Yes! Topical tranexamic plays nice with other brightening agents, including vitamin C, so in most cases it's totally safe to use the two together. In fact, doubling up on brighteners may help fade your dark spots and hyperpigmentation even fast.

How to layer tranexamic acid?

Layering Tranexamic Acid and Niacinamide

However, it is most common to find tranexamic acid in serum form, which can be used immediately before niacinamide. In the morning, use tranexamic acid and niacinamide before sunscreen; at nighttime, layer it under your preferred retinoids/retinol.

What should you not mix with vitamin C serum?

Beta Hydroxy Acids

So that salicylic acid of yours should not be mixed with your vitamin C serum. It won't be able to help you with discoloration, collagen production, or protect you from UV rays. Additionally, combining the two can cause irritation and dryness.

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