What autoimmune disease causes burning sensation?

Author: Preston D'Amore MD  |  Last update: Wednesday, December 3, 2025

Erythromelalgia is a rare condition that primarily affects the feet and, less commonly, the hands (extremities). It is characterized by intense, burning pain of affected extremities, severe redness (erythema) and increased skin temperature that may be episodic or almost continuous in nature.

Does lupus feel like burning?

The main symptoms of cutaneous lupus are the skin changes described above that occur with each variation of the condition. Other symptoms that can occur include: Itchiness in the skin. Burning in the skin.

What are three signs of Sjögren's syndrome?

Other symptoms of Sjögren's syndrome can include:
  • dry skin that may be itchy.
  • a cough that does not go away.
  • a quiet or hoarse voice.
  • an unpleasant taste in you mouth caused by stomach acid (acid reflux)
  • swollen glands in your cheeks, neck and under your jaw (salivary glands)
  • vaginal dryness.

What are the symptoms of autoimmune nerve damage?

Symptoms can range from numbness or tingling, to pricking sensations (paresthesia), or muscle weakness. Areas of the body may become abnormally sensitive leading to an exaggeratedly intense or distorted experience of touch (allodynia).

What neurological disorder causes burning skin sensation?

Dysesthesia causes painful, itchy, burning, or restrictive sensations without an immediate trigger. It occurs due to nerve damage and is common in multiple sclerosis, diabetes, and shingles.

Common Autoimmune Diseases: Causes and Symptoms

What does MS burning feel like?

Dysesthesia includes symptoms such as burning or stinging, pins and needles sensation, electrical sensations, itching, discomfort, or pain. It is described by patients as a skin-on-fire feeling, or that the body feels like burning. These symptoms may vary in intensity among individuals and over time.

What is the hardest autoimmune disease to diagnose?

Vasculitis: Vasculitis involves inflammation of blood vessels, leading to various symptoms depending on the affected organs. The diagnosis often requires imaging studies and biopsies, making it one of the more challenging autoimmune diseases to identify.

What is the sister disease to MS?

Neuromyelitis optica is often misdiagnosed as multiple sclerosis, also known as MS, or is seen as a type of MS . But NMO is a different condition. Neuromyelitis optica can cause blindness, weakness in the legs or arms, and painful spasms.

What are the warning signs of Guillain-Barre syndrome?

Symptoms of Guillain-Barre syndrome may include:
  • A pins and needles feeling in the fingers, toes, ankles or wrists.
  • Weakness in the legs that spreads to the upper body.
  • Unsteady walk or not being able to walk or climb stairs.
  • Trouble with facial movements, including speaking, chewing or swallowing.

What organ fails with Sjögren's?

While many patients experience dry eyes, dry mouth, fatigue and joint pain, Sjögren's can also cause dysfunction of organs such as the kidneys, gastrointestinal system, blood vessels, lungs, liver, pancreas, and the central nervous system.

What autoimmune disease affects your eyes?

Sjogren's syndrome

This autoimmune disease causes chronic inflammation of the tear glands and leads to severe dry eyes. People who have Sjogren's syndrome may also get perforations in the cornea.

What autoimmune disease causes burning?

Erythromelalgia is a rare disorder that can affect your feet, hands and other areas. Symptoms may come and go. They include skin redness and an intense burning sensation. This can make sleeping, walking and other tasks challenging.

What is lupus belly?

Lupus can also cause other problems in the abdomen, including peritonitis (inflammation of the abdominal lining) and ascites (a build-up of fluids in the abdomen). Symptoms of peritonitis and ascites include: Abdominal pain and swelling. Nausea and vomiting.

What is the most common neurological autoimmune disease?

If you have a neurological autoimmune disease, your immune system may be overly active and mistakenly attack healthy cells. The most common of these is multiple sclerosis (MS).

What are MOG disease symptoms?

Symptoms of MOG Antibody Disease

MOGAD causes inflammation on the brain, spinal cord and/or optic nerves and can result in the following symptoms: Lost or blurred vision in one or both eyes. Loss of color vision. Pain in the eyes, back, legs, arms or chest area. Paralysis or weakness in arms and legs.

What mimics multiple sclerosis?

Mayo Clinic: "Diabetes," "Diabetic neuropathy," "Diabetic retinopathy," "Lupus," "Parkinson's disease," "Myasthenia gravis," "Amyotrophic lateral sclerosis (ALS)," "Guillain-Barre syndrome," "Peripheral neuropathy," "Lyme disease," "Sjogren's syndrome."

What disease did Ashton Kutcher have?

Actor Ashton Kutcher's rare autoimmune condition, vasculitis, is a disorder characterized by inflammation of the blood vessels that can be life-threatening.

What is the rarest autoimmune disease?

Asherson's syndrome is an extremely rare autoimmune disorder characterized by the development, over a period of hours, days or weeks, of rapidly progressive blood clots affecting multiple organ systems of the body.

What autoimmune disease affects your legs?

Myositis usually affects the muscles you use to move, including muscles in your: Arms and shoulders. Legs and hips.

What are MS Zingers?

MS “zingers” refer to neuropathic sensations, such as pain or pins and needles, caused by multiple sclerosis-related damage. Treatment can involve medical treatment and avoiding triggers. Do you ever feel sharp, prickling, radiating pain that seems to come out of nowhere?

What is the hot bath test for MS?

The hot bath test involved lying in a bath of warm water. If this caused or worsened neurological symptoms, it was taken as evidence that the person had multiple sclerosis. This test has not been used for many years. The hot bath test reflects the effect of heat that many people with MS notice.

Previous article
What is the normal bra size for a 25 year old?
Next article
What products can I use after laser?