What antibiotic kills propionibacterium?

Author: Jack Ryan  |  Last update: Sunday, June 22, 2025

Medication Summary Antibiotics used to treat anaerobic infections usually suffice for other types of Cutibacterium infections. C acnes generally is highly susceptible to a wide range of antibiotics. These include the penicillins, carbapenems, and clindamycin. In addition, vancomycin and teicoplanin have been used.

What kills Propionibacterium bacteria?

For systemic P. acnes infections, treatment with penicillin or vancomycin has proven to be effective, although P. acnes biofilm formation can limit the access of antibiotics to the site of infection.

Does doxycycline treat Propionibacterium?

Results. P. acnes was isolated from 227 patients; 224 isolates (98.7%) were susceptible to doxycycline and 220 (96.9%) were susceptible to tetracycline, followed by clindamycin and clarithromycin in 101 (44.5%) and 102 (44.93%) isolates, respectively.

How do you treat a joint infection with Propionibacterium acnes?

Propionibacterium-associated PJI treated with surgery in combination with long-term antibiotic administration had a successful outcome at 1- and 2-year follow-up irrespective of whether the patient was treated with rifampicin.

How do you treat Propionibacterium endocarditis?

Benzyl-penicillin should be the first-line antibiotic treatment option for IE caused by Propionibacterium spp.

Acne Vulgaris - Propionibacterium acnes - Acne Treatment - Microbiology & Infectious Diseases

What oral antibiotics treat Propionibacterium?

Antibiotics used to treat anaerobic infections usually suffice for other types of Cutibacterium infections. C acnes generally is highly susceptible to a wide range of antibiotics. These include the penicillins, carbapenems, and clindamycin. In addition, vancomycin and teicoplanin have been used.

What oral antibiotics treat bacterial endocarditis?

Oral therapies included beta-lactams (amoxicillin, penicillin V, ampicillin, cloxacillin and dicloxacillin) - with or without probenecid - in five (56%) studies [11-15]; fluoroquinolones (ciprofloxacin) in combination with rifampin in one (16%) [10]; and sulfonamide, aureomycin and linezolid in one study each [9,16,17] ...

What drugs are used to treat Propionibacterium?

The penicillins (penicillin G and amoxicillin) and cephalosporins (cephalothin and ceftriaxone) showed strong activity against P. acnes, with many isolates showing MICs lower than the lowest antibiotic concentration on the Etest strip.

How do you treat bacterial joint inflammation?

The infection can quickly and severely damage the cartilage and bone within the joint, so prompt treatment is crucial. Treatment involves draining the joint with a needle or during surgery. Antibiotics also are usually needed.

What is the name of the disease that is caused by Propionibacterium acnes?

Propionibacterium acnes is a gram-positive human skin commensal that prefers anaerobic growth conditions and is involved in the pathogenesis of acne (Kirschbaum and Kligman, 1963). Acne is one of the most common skin diseases, affecting more than 45 million individuals in the United States.

Which antibiotic is Propionibacterium acnes extremely sensitive to?

Overall, antibiotics have been used for the acne treatment for several decades, and the antibiotic resistance of P. acnes is a result of antibiotic use in the treatment of acne. P. acnes was highly sensitive to cyclines (doxycycline and tetracycline).

How long does doxycycline take to clear bacteria?

For example, it may take up to 24 to 48 hours (1 to 2 days) for a fever, a common symptom of bacterial infections, to improve. But this can vary based on the infection you're treating and how severe it is. It typically takes 1 to 2 weeks for doxycycline to completely clear an infection.

What is a common use for Propionibacterium?

In ruminants, propionibacteria reduce nitrate to nontoxic nitrogen compounds. Members of the genus Propionibacterium are widely used in the production of vitamin B12, tetrapyrrole compounds, and propionic acid, as well as in the probiotics and cheese industries.

What are the diseases caused by Propionibacterium?

They are found in acne, prosthetic joints, cerebrospinal fluid shunts, endocarditis, and osteomyelitis. They have been identified as a cause of postoperative endophthalmitis of a chronic granulomatous nature, almost exclusively found in patients with intraocular lenses (IOLs).

What is the strongest natural antibiotic for acne?

The most common natural acne treatments include:
  • Aloe vera. The gel from the aloe vera plant has a reputation as a skin soother. ...
  • Apple cider vinegar. Apple cider vinegar has a reputation as a natural cure for many conditions, including acne. ...
  • Green tea. ...
  • Honey. ...
  • Tea tree oil. ...
  • Turmeric. ...
  • Zinc. ...
  • Sulfur.

What does Propionibacterium acnes feed on?

In acne, the bacteria known as Propionibacterium acnes (or P. acnes for short) can have an effect on the development acne 'lesions' (e.g. spots). P. acnes lives on the skin and is commonly found within hair follicles, where it feeds on dead skin cells and sebum, which is the oil produced by your skin.

How do you get rid of bacterial inflammation?

Serious bacterial infections can be effectively treated with antibiotics. These medicines either kill the bacteria or stop them multiplying. This helps your body's immune system fight the bacteria. Your doctor's choice of antibiotic will depend on the bacteria that is causing your infection.

What is the fastest way to reduce joint inflammation?

RICE method.

If you think your joint inflammation is due to a sudden injury, the RICE (rest, ice, compression, and elevation) method is the first line of treatment to reduce pain and swelling. See an orthopedist if the pain and swelling don't diminish after RICE treatment.

How to reduce Propionibacterium?

Benzoyl peroxide (BPO) is a bactericidal agent commonly used for treating acne vulgaris and has been shown in multiple randomised studies to reduce the prevalence of P acnes on the shoulder [10,12,14]. Application of 5% BPO three days prior to surgery has been shown to effectively reduce P acnes culture [11,12,14].

What is the new name for Propionibacterium?

The skin commensal Propionibacterium acnes, recently renamed Cutibacterium acnes, along with the other major pathophysiological factors of increased seborrhea, hyperkeratinization of the pilosebaceous unit, and inflammation, has long been implicated in the pathogenesis of acne.

What naturally kills P. acnes?

Tea tree oil is a natural antibacterial and anti-inflammatory, which might kill P. acnes, the bacteria that causes acne.

What is the first line antibiotic for endocarditis?

Culture-negative NVE is usually treated with vancomycin and gentamicin. In patients who previously have received antibiotics, initial therapy should consist of either ampicillin-sulbactam plus gentamicin (3 mg/kg/d) or vancomycin plus gentamicin and ciprofloxacin.

What is the life expectancy of someone with endocarditis?

Conclusions: Long term survival following infective endocarditis is 50% after 10 years and is predicted by early surgical treatment, age < 55 years, lack of congestive heart failure, and the initial presence of more symptoms of endocarditis.

What is a broad spectrum antibiotic for endocarditis?

The term "broad spectrum antibiotics" was originally used to designate antibiotics that were effective against both gram-positive and gram-negative bacteria, in contrast to penicillin, which is effective chiefly against gram-positive organisms, and streptomycin, which is active primarily against gram-negative bacteria.

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