One of the tretinoin creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by the damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and slowing down the way the body removes skin cells that may have been harmed by the sun.
To use the cream, gel, or lotion form of this medicine: Apply just enough medicine to very lightly cover the affected areas, and rub in gently but well. A pea-sized amount is enough to cover the whole face. You may need to use a moisturizer while you are using the lotion.
If you stop using the medication or are inconsistent with your treatment, any improvements you see may disappear over time. Always use the product as prescribed by your healthcare provider (Rodan, 2016).
It may take longer than 12 weeks before you notice full improvement of your acne, even if you use the medicine every day. Check with your doctor if skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks.
"You can use tretinoin or [over-the-counter] retinols forever."
Generally, it is fine to use tretinoin every night, but you may not want to because of the initial side effects, especially when you first start. You should only use tretinoin as prescribed to avoid significant skin irritation, redness, and other side effects.
Tretinoin is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Tretinoin is classified as a "retinoid." (For more detail, see "How Tretinoin Works" section below).
After 4-6 weeks, your skin will get used to tretinoin and will begin to be noticeably smoother and more even. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.
As a result of its effects on your skin's cellular turnover speed, tretinoin reduces the appearance of wrinkles, evens out your skin's pigmentation and also treats skin issues such as acne. The end result is smoother, younger looking skin that's much less affected by fine lines, wrinkles or other common signs of aging.
Yes. It's perfectly safe to use a moisturizer with tretinoin. In fact, tretinoin without moisturizer is generally not recommended. Many dermatologists advise their patients to moisturize while using it to reduce their chance of developing dry, peeling skin.
Tretinoin strength studies
While both were equally effective over a one year period, Tretinoin 0.1% was able to achieve cosmetic improvement in 6 months while 0.05% required closer to 12 months. Finally, 0.025% was compared to 0.1% and it was found that both produced similar improvements in photoaging.
In simple terms, tretinoin not only produces an improvement in skin quality and a reduction in wrinkles in short-term studies -- it's also highly effective at reducing wrinkles, discoloration and other signs of aging when used over the long term.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
For the purposes of skin care, tretinoin can be thought of as a more concentrated version of retinol. This means that tretinoin is stronger than retinol. This difference in strength can help guide your decision-making when it comes to choosing a skin care product. Your skin is affected by more than what you put on it.
Tretinoin Does Not “Bleach” Your Skin
Contrary to popular belief, tretinoin is not a “bleaching agent” or medicine designed specifically to lighten your skin tone. While tretinoin can even out patches of hyperpigmentation and cause a mild change in your skin tone, it doesn't affect melanin synthesis.
Tretinoin gel, cream, or lotion requires a prescription because it's more powerful than retinol. Doctors prescribe tretinoin to treat skin conditions like: Acne. Psoriasis.
Unless your doctor tells you otherwise, it is especially important to avoid using the following skin products on the same area as tretinoin: Any other topical acne product or skin product containing a peeling agent (eg, benzoyl peroxide, resorcinol, salicylic acid, or sulfur).
In the morning, wash your face with a mild facial scrub or rough washcloth. This will help reduce the noticeable flaking. After washing, apply a good water-based moisturizer. The moisturizer will make the drying effect of the medicine more tolerable.
Tretinoin minimizes pore appearance by increasing cell turnover and boosting exfoliation, which clears debris in the pores and allows pores to shrink back to their normal size.
Tretinoin for Hair Loss — The Science
In this study from the Journal of Investigative Dermatology on the effects of oral retin a — oral tretinoin — on human scalp hair follicles, research showed that exposure to retinoic acid induced premature hair follicle regression.
It belongs to a group of drugs called retinoids, these are similar to vitamin A. It is not a chemotherapy drug, but you may have it with chemotherapy drugs to treat a type of acute myeloid leukaemia called acute promyelocytic leukaemia (APL or APML).
If it sounds a little grim, it's because it kind of is. But it's important to keep in mind that skin peeling is a normal effect of tretinoin treatment and not something to be overly alarmed about.
Just make sure you choose products without synthetic fragrances to keep irritation at bay. When starting out, apply moisturizer directly after applying tretinoin to minimize potential irritation. As your skin adjusts, you can leave tretinoin on for about 20 minutes before following up with a moisturizer.
Sheila Krishna, it's totally fine to use vitamin C with over-the-counter retinol products or dermatologist-grade retinoids—which, BTW, is the broader term for vitamin A derivatives, including retinol, tretinoin, and adapalene, just to name a few.