However, while The Spot Cream is generally safe, one of the high-strength ingredients in a few of the formulas is hydroquinone, which could rarely lead to some serious health risks. And while Musely's 60-day Result Guarantee sounds generous, it's quite strict and requires a commitment to regular mobile app check-ins.
However, 4% Hydroquinone is a better topical hypopigmenting agent with rapid rate of clinical improvement when compared to 0.75% Kojic Acid cream. The side effects of both the hypopigmenting agents were not significant.
As with any prescription medication, symptoms may reappear if a person stops using Musely products.
While oral consumption probably is not related to topical application, hydroquinone remains controversial because it actually is toxic to melanocytes. Hydroquinone, a phenolic compound chemically known as 1,4 dihydroxybenzene, functions by inhibiting the enzymatic oxidation of tyrosine and phenol oxidases.
Hydroquinone has also frequently been misused. It must not be used as an all-over skin lightening treatment and such procedures should be avoided. After much research, dermatologists have concluded that, in low concentrations, hydroquinone is safe to use and can produce some excellent results.
Sunscreen should be applied to the affected areas after hydroquinone to avoid relapse of the condition. Dark areas may recur if the cream is discontinued but this is less likely happen if sun protective measures are followed.
However, while The Spot Cream is generally safe, one of the high-strength ingredients in a few of the formulas is hydroquinone, which could rarely lead to some serious health risks. And while Musely's 60-day Result Guarantee sounds generous, it's quite strict and requires a commitment to regular mobile app check-ins.
Our doctors recommend avoiding benzoyl peroxide, as it is known to decrease the stability of tretinoin and may cause staining when used with hydroquinone. Also, abrasive cleansers (e.g., face wash with glycolic or AHA/BHA acids) can make the skin more sensitive and should be avoided.
We recommend taking a 2 month break after 3 months of application. Since hydroquinone is a photosensitive agent, It is also important to use SPF 30 or higher daily when on hydroquinone.
Tretinoin is an anti-aging powerhouse, meaning it should have no problem dispatching fine lines and wrinkles. It does not work for deeper wrinkles. Hydroquinone doesn't work at all against fine lines and wrinkles, so stick to the collagen-boosting power of tretinoin.
Avoid using hydroquinone with peroxide products such as benzoyl peroxide or hydrogen peroxide, which can cause discoloration. 3. Avoid alpha hydroxy acids. The combination of hydroquinone and alpha hydroxy acids (AHAs) can irritate your skin.
With GRAS (Generally Recognized as Safe) status, hexylresorcinol is a great choice for beauty brands seeking to provide skin lightening and even toning benefits in their next skin care formula. Hexylresorcinol was introduced to the skin care market in 2007 under the trade name Synovea® HR.
Hydroquinone. Topical HQ is regarded as the gold standard for the treatment of facial hyperpigmentation. HQ is a bleaching agent that acts by inhibiting tyrosinase to limit melanin production in the skin.
Unlike retinol, hydroquinone isn't a skincare product you can use indefinitely because the skin can develop resistance, making it ineffective over time. Plus, prolonged use increases the risk of ochronosis – a nasty condition where the skin darkens instead of lightening.
Amazon.com: Musely - Facial Treatments & Masks / Facial Skin Care Products: Beauty & Personal Care.
Musely FaceRx treatments are available exclusively through musely.com. This model allows us to offer effective, highly potent medications that are 10x more affordable than in-person or online alternatives. Our prescribers are Board-Certified Dermatologists who are the most highly trained and specialized in their field.
Over-the-counter products can contain 0.5% to 2% concentrations. At the pharmacy, 4% concentrations of hydroquinone (and sometimes even higher) are available by prescription only. A concentration of 12% hydroquinone actually prevents the production of melanin altogether.
As a rule, you should stop using hydroquinone after 3-6 months of continuous use. This is because prolonged use of hydroquinone can lead to adverse effects on the skin, such as ochronosis, skin irritation, and sensitivity. There are several signs that it may be time to stop using hydroquinone.
Hyperpigmentation may be sun damage and sun spots if you have a history of chronic sun exposure and tanning. Melasma often presents as broad patches of discoloration, whereas sun spots and other forms of hyperpigmentation may look like small circles or focused dots.
FDA has received reports of serious side effects including skin rashes, facial swelling, and ochronosis (discoloration of skin) from the use of skin lightening products containing hydroquinone.
Alternative lightening agents including mequinol, arbutin, kojic acid, and others have shown comparable efficacy to hydroquinone in treating hyperpigmentation with less concerning side effects.
Side effects that you should report to your doctor or health care professional as soon as possible: severe burning, itching, crusting, or swelling of the treated areas. unusual skin discoloration.