Salicylic acid and vitamin C are both effective products on their own but, when combined, they can be even more beneficial. Whether you're looking to brighten your skin, reduce the likelihood of blemishes or just help slow down the skin's natural aging process, these ingredients may be just what you're looking for.
It's generally recommended to avoid combining products with salicylic acid and vitamin C directly, as they may counteract each other's effectiveness. Salicylic acid is acidic and could potentially destabilize vitamin C.
Retinol: As Retinol and Salicylic Acid are both exfoliating, drying skincare ingredients, using both together in the same routine could lead to serious irritation. Glycolic Acid: Similarly, as an AHA, Glycolic Acid helps exfoliate the top layer of the skin, which is too intense when used alongside Salicylic Acid.
Vitamin C should not be mixed with acids, which includes all AHAs and BHAs. Vitamin C plays a key role in strengthening the outer layer of our skin barrier, but when combined with an acid, it can enhance the potency of your vitamin C and cause severe irritation [5].
Vitamin C (Ascorbic Acid) is most effective when the skin's pH is around 2 or 2.5. Using BHA (Salicylic Acid) products first can help your skin get the most benefit from the Vitamin C serum. However, if you'd like to support the channel, you can do so with a tip here: https://paypal.me/vand...
Layer From Lightest To Heaviest Formulas
 As a general rule of thumb, apply your products in this order: cleanser, toner/essence, treatment/mask, serum, eye cream, moisturizer, oil, SPF. Sunscreen always goes last, and the only thing that you should layer over sunscreen is powder, concealer, or foundation.”
It is safe to use products with salicylic acid in everyday skin care, unless it is specified otherwise on the product usage guidelines or by your health care professional. CeraVe's Salicylic Acid range includes products such as Cerave's SA Smoothing Cream and SA Smoothing Cleanser that are suitable for daily use.
Possible interactions include: Aluminum. Taking vitamin C can increase your absorption of aluminum from medications containing aluminum, such as phosphate binders. This can be harmful for people with kidney problems.
Vitamin C + Niacinamide
 However, when you combine niacinamide with Vitamin C, they'll cancel each other out chemically, making both formulas ineffective on your skin. Niacinamide takes out all the good properties of Vitamin C and makes it into a substance that can cause redness and trigger breakouts.
Don't Mix with Certain Ingredients:
 Avoid applying Vitamin C with products containing AHAs, BHAs, retinol, or benzoyl peroxide in the same routine. These ingredients have different pH levels that can clash with vitamin C, reducing its effectiveness and potentially causing irritation.
Retinol and Salicylic Acid
 Both of these ingredients are two of the most potent blends in the plethora of skincare products. Combining both of these together will act as a super charged, double intense skin nightmare resulting in severe dryness, sensitivity and an increase in skin photosensitivity.
Using Salicylic Acid with Retinol or Benzoyl Peroxide can dry out the skin, causing flakiness and redness.
While you can work your vitamin C serum into either your morning or evening skincare routine, most dermatologists recommend the morning [2]. This keeps your skin protected from free radicals as you go about your day, and can work especially well with your sunscreen to keep you safe from UV radiation.
Vitamin C usually has a pH of 3 or lower. If you are not cautious, mixing vitamin C with salicylic acid can reduce the effectiveness of vitamin C. Mixing the two together may also cause irritation for sensitive skin. To avoid this, it is best to use the two at opposite ends of your skincare routine.
Vitamin C is effectively an acid (it's sometimes known as ascorbic acid), so layering it with AHAs and BHAs like glycolic, salicylic, and lactic acids is a big no-no.
"If salicylic acid is an ingredient in your cleanser, it is fine to use it every day." However, if you are using an exfoliant that has salicylic acid in the formula, Dr. Hu advised only using the product three times per week to avoid over-exfoliating the skin and drying it out.
Salicylic acid is best applied to dry skin, whereas hyaluronic acid is best applied to damp skin and then sealed in with a thicker moisturizer/occlusive. Damp skin is more porous, allowing skincare components to enter the skin's barrier more easily.
Salicylic acid can be drying to the skin, so it's important to moisturize your skin after using it. Look for a moisturizer that is lightweight, non-comedogenic, and free of fragrances and other irritants. Moisturizing after using salicylic acid can help to soothe the skin and prevent dryness and irritation.
If you've recently started using a product containing retinoids or chemical exfoliants such as glycolic or salicylic acid, there's a good chance your skin is feeling the purge. These ingredients work quicker by helping bring impurities to the surface and small red bumps can actually be a sign the product is working.