The time it takes to start fading hyperpigmentation varies depending on severity and whether you're using Tretinoin alongside Hydroquinone. Noticeable improvements in skin tone may start after as little as 6-8 weeks or as much as 3-6 months of regular use.
If you're using topical tretinoin to reduce wrinkles, discoloration, age spots, and/or rough feeling skin, it can take 3–4 months or up to six months before you see results. If you stop using the medication or are inconsistent with your treatment, any improvements you see may disappear over time.
One of the tretinoin creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by the damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and slowing down the way the body removes skin cells that may have been harmed by the sun.
With 12 weeks of consistent tretinoin usage, you'll start seeing a significant improvement in the skin damage caused to the skin by sun exposure. There is a reduction of sun-induced yellowish thick appearance of the skin, sun spots, coarse wrinkles, and uneven pigmentation due to sunburns.
Tretinoin increases cell turnover which improves the delivery and absorption of Hydroquinone into the skin. Additionally Tretinoin promotes collagen and elastin production. This to improves skin thickness and elasticity which makes hyperpigmentation look less pronounced.
For experienced retinoid users and those with severe acne, hyperpigmentation or wrinkles, 0.1% Tretinoin strength may be needed. This highest concentration is up to 20X stronger than retinol.
Retinoids have been implicated in causing mild-to-moderate elevations in routine liver tests, but these elevations are usually asymptomatic and transient, resolving spontaneously even with continued therapy.
After 4-6 weeks, your skin will get used to Tretinoin and will begin to be noticeably smoother and more even. Depending on how often you use Tretinoin, you may begin to see full benefits by this point. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.
Age spot treatments include: Medications. Applying prescription bleaching creams (hydroquinone) alone or with retinoids (tretinoin) and a mild steroid might gradually fade the spots over several months. The treatments might cause temporary itching, redness, burning or dryness.
Retinoic Acid-APL Syndrome: Patients treated with tretinoin have experienced retinoic acid-APL (RA-APL) syndrome characterized by fever, dyspnea, acute respiratory distress, weight gain, radiographic pulmonary infiltrates, pleural and pericardial effusions, edema, and hepatic, renal, and multi-organ failure.
In general, Hydroquinone is a powerful skin-lightening agent often compounded with Tretinoin to target hyperpigmentation and melasma. In addition to its own skin brightening effects, Tretinoin also enhances Hydroquinone's penetration. As such this duo work well together to tackle dark spots and uneven discolouration.
Applying excessive amounts of tretinoin onto the skin to make acne go away faster will not work. This can make the skin worse by causing extreme dryness, peeling, or redness. It may take up to six weeks of tretinoin treatment to see results. Make sure to use sunscreen, especially in the summertime.
Skin purging typically lasts anywhere between four to six weeks which is roughly in line with how long it takes for your skin cells to naturally turnover. During this phase, it might seem like your skin is getting worse but it should settle down and improve after you've passed this period.
Retinol for dark spots
Some people find that topical retinol lightens their skin spots, though it takes months and can be irritating to your skin. It's a good idea to see a dermatologist (a medical doctor who specializes in conditions of the skin) if you're concerned about dark spots.
Three inexpensive moisturizers that our physicians love are Vanicream Daily Facial Lotion with Hyaluronic Acid, Neutrogena Hydroboost Gel, and The Ordinary Hyaluronic Acid Serum. All three of these are affordable, non-comedogenic,and blend well with tretinoin.
Some people may experience side effects when using tretinoin, especially as their skin adjusts. Also, it's possible for irritation from tretinoin to make skin darker, especially if you have more melanated skin.
If you want to get rid of dark spots fast, a procedure that removes layers of discolored skin may work better than a lightening cream. These techniques include laser treatments, freezing (cryotherapy), dermabrasion, microdermabrasion, microneedling, and chemical peels.
However, most people will see noticeable results after at least 6-12 weeks of consistent use. In terms of anti-aging benefits, such as reducing fine lines and improving skin texture or smoothing pores, the results usually take longer.
Unlike over-the-counter anti-aging products, tretinoin has anti-aging ingredients that go deep beneath the outer portion of the skin to the epidermis. It boosts the production of new collagen in around six months, resulting in smoother, younger-looking skin.
You should aim to use tretinoin every night, however, you must start slowly as your skin needs to get used to it. The first 2 weeks apply it 2 to 3 nights per week, after that try applying it every other day, and then if your skin can handle it, apply it every night.
For those of us who do suffer from purging, it can look like: breaking out in pustules (pimples), the appearance of flaky, peeling skin, irritation and dry patches. Getting these symptoms can be demotivating, especially if you're already feeling unconfident about your skin.
Start small and increase slowly
When you first start using tretinoin, you may start with a lower percentage that you apply just two or three times a week. After two weeks, if your skin is adjusting well to the tretinoin, you can consider increasing use to every night as tolerated.
Topical tretinoin can cause your skin to become dry, red, swollen, blistered, or flaky. It may also cause your skin to itch, be painful, or feel like it is burning. Stop using topical tretinoin and call your healthcare provider if these symptoms become worse or do not go away.
Fans of retinoids often boast of an effect called “tret glow”, which is the glowing complexion they get after using the product for a while. You can get that glow faster and treat underlying skin concerns with the following aesthetic treatments to enhance your retinoid results.
Tretinoin counteracts the destruction of collagen and elastic fibers by inhibiting the regulation of MMPs.