After 4-6 weeks, your skin will get used to tretinoin and will begin to be noticeably smoother and more even. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.
You may notice tretinoin starting to work within 2 to 3 weeks, but it can take 6 weeks or more to experience the full benefit. If you don't see improvement within 12 weeks, or if you have significant improvement and wonder if you should start using it less frequently, talk to your doctor.
While prescription-strength retinoids may have an effect in a matter of weeks, it can take up to 6 months for OTC retinols to produce the same results. You may notice a difference in conditions like acne after 12 weeks, but sun damage and signs of aging can take much, much longer to improve.
These unwanted effects — particularly skin dryness and acne breakouts — are widely referred to as the “tretinoin purge.” While they don't affect everyone, many tretinoin users experience some degree of purge effects during the first several weeks of treatment.
Because tretinoin is retinoic acid, it can cause temporary redness, itching, and sometimes peeling when first applied. That's the tretinoin purge.
Skin purging typically looks like tiny red bumps on the skin that are painful to touch. They are often accompanied by whiteheads or blackheads. It can also cause your skin to become flaky. The flare ups caused by purging have a shorter lifespan than a breakout.
Generally speaking, dermatologists say purging should be over within four to six weeks of starting a new skin care regimen. If your purge lasts longer than six weeks, consult your dermatologist. It could be that you need to adjust the dosage and/or frequency of application.
Remember, that 'retinoid uglies' are likely to be temporary, and it will take time before you see the end result. You have three skin layers—the epidermis, dermis, and subcutaneous tissue. Your epidermis is your visible layer, and renews approximately every 28 days.
Tretinoin purging is when the skin gets worse before it gets better. Tretinoin speeds up the skin cell turnover process, causing some initial breakouts, drying, and peeling. These symptoms eventually go away and leave clearer skin underneath.
For the purposes of skin care, tretinoin can be thought of as a more concentrated version of retinol. This means that tretinoin is stronger than retinol. This difference in strength can help guide your decision-making when it comes to choosing a skin care product. Your skin is affected by more than what you put on it.
If you're using topical tretinoin to reduce wrinkles, discoloration, age spots, and/or rough feeling skin, it can take 3–4 months or up to six months before you see results.
“Retinoids break down quickly when exposed to sunlight. For that reason, it's best to use a retinol product at night when skin repairs itself,” explained Dr. Haberman. “In general, anti-aging ingredients will be more effective if applied before bedtime,” he added.
Tretinoin Does Not “Bleach” Your Skin
Contrary to popular belief, tretinoin is not a “bleaching agent” or medicine designed specifically to lighten your skin tone. While tretinoin can even out patches of hyperpigmentation and cause a mild change in your skin tone, it doesn't affect melanin synthesis.
The only skin care product that can truly provide a slight tightening effect with regular use is Retin A, or Tretinoin. This is because Vitamin A helps speed up skin cell turnover, helping to boost collagen production.
Tretinoin for acne scars
Tretinoin can also be used to decrease the appearance of acne scarring. Since tretinoin speeds up cell turnover on your skin, it can encourage new cell growth at the site of your scarring. Tretinoin in several forms has been tested successfully as an effective way to treat acne scars.
During the first 3 weeks you are using tretinoin, your skin may become irritated. Also, your acne may seem to get worse before it gets better. It may take longer than 12 weeks before you notice full improvement of your acne, even if you use the medicine every day.
Purging is slightly different, appearing on the skin mostly as blackheads or small skin-coloured bumps just under the surface of the skin. But it is also possible for purging to cause similar spots to a breakout, too.
Generally, it is fine to use tretinoin every night, but you may not want to because of the initial side effects, especially when you first start. You should only use tretinoin as prescribed to avoid significant skin irritation, redness, and other side effects.
Purging usually lasts between two to four weeks, according to Dr Phillips. “Efficacy is partly determined by the formulation and strength of the product; however, on average, most people will start to see a difference after a month,” he says.
How to treat skin purging. “If the skin barrier is compromised when you see purging then start ingredients which help with barrier repair, such as ceramides and hyaluronic acid in a non-comedogenic formulation. If you are using a treatment or product continue with a slower approach.”
Purging is a sign that the product is working and you should continue with the treatment as prescribed. After a few weeks of purging, your skin and acne will have noticeably improved. Breaking out is when your skin is reacting because it is sensitive to something in the new product.
Tretinoin minimizes pore appearance by increasing cell turnover and boosting exfoliation, which clears debris in the pores and allows pores to shrink back to their normal size.
Tretinoin is used to treat acne or other skin diseases as determined by your doctor. It works partly by keeping skin pores clear. One of the tretinoin creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by the damaging rays of the sun.
Tretinoin can help dark spots fade, allowing you to have a more even skin tone. It decreases the amount of melanin in your skin cells (Zasada, 2019). When used for discoloration, tretinoin is usually combined with other skin-lightening products, sometimes in the form of a chemical peel (Lawrence, 2021).
To maximize your results from tretinoin and reduce your risk of side effects, it's best to pick a moisturizer that's 100 percent free of alcohol, benzoyl peroxide, artificial fragrances, salicylic acid or any other peeling agent or ingredient that has irritated your skin in the past.