“The fastest way [to get rid of a pimple] is to go to your dermatologist and get a cortisone shot,” says Dr. Friedier. Most of the time, she says, this steroid injection, which goes straight into the lesion, brings down the inflammation, swelling, and pain from a gnarly pimple within 24 hours.
"The most common way to address these issues is to use benzoyl peroxide, sulfur, tree oil, or salicylic acid products before you go to bed," says Dr. Patel. Benzoyl peroxide is a bleaching agent that kills microbes and dries up oil in the follicle.
Only a doctor should inject a corticosteroid. To remove a large pimple or painful acne cyst or nodule, your dermatologist may also use a procedure called incision and drainage. It involves using a sterile needle or surgical blade to open the blemish and then removing what's inside.
Salicylic Acid
Used overnight, products containing salicylic acid can be effective at reducing the effects of blemishes by the morning. A good salicylic acid treatment will do more than just shrink a pimple, however.
If you've only got a few hours…
Grab an ice pack, or a single ice cube if your fingers can bare it, and apply it directly onto your pimple. Hold it this way for as long as you can stand it, then take a break for a few seconds, and repeat at least twice more.
Try a spot treatment or pimple patch
You've probably seen these emergency pimple treatments at the drugstore — usually an extra-strong solution of salicylic acid, glycolic acid, or benzoyl peroxide. And yep, they can actually get rid of pimples overnight.
Many people find relief from nodular acne after receiving treatments from a dermatologist. But it can take time for the nodules to go away. Keep in mind that you may need to try different types of treatments or combinations of medications to achieve results.
The best way to make a zit go away fast is to apply a dab of benzoyl peroxide, which you can buy at a drug store in cream, gel or patch form, says Shilpi Khetarpal, MD. It works by killing bacteria that clogs pores and causes inflammation.
Your best bet for quickly calming things down and reducing the size of your breakout is to treat it with ice (FYI, cold has anti-inflammatory properties). Simply wrap an ice cube in a clean towel and hold it to your pimple on-and-off for five minutes. You can also use an ice roller or cryo balls if you have them handy.
Apply a warm compress
Applying a warm compress can help to treat a blind pimple. The heat can open up pores, which may draw the pimple closer to the skin's surface and create a head. The formation of a head enables the sebum, cells, and bacteria to exit the skin.
For severe acne, hydrocortisone injections inserted directly into the lesions can shrink them, speed healing, and improve inflammation; it's considered an effective treatment that can prevent or minimize scarring.
Pores in the skin can clog with excess oil and dead skin cells, causing pimples. Bacteria can enter the skin pores and get trapped along with the oil and skin cells. The skin reaction causes swelling deep in the skin's middle layer (the dermis). This infected, red, swollen lump is an acne cyst.
Get a Cortisone Injection
The breakout completely flattens out within 48 hours generally. Large, deep blemishes usually don't respond well to other treatments, so if you absolutely need that breakout gone quickly a cortisone shot is your best bet.
Blind pimples usually go away in about a week or two with the proper treatments. But they can linger under your skin for a few months, causing pain and irritation. In severe cases, the oil and dead skin cells can block the pores deep under your skin, which traps bacteria and causes an infection.
Blind pimples are typically caused by a cyst or nodule that develops underneath the skin. They develop when sebum, dirt, and bacteria get trapped in a hair follicle. If you have oily skin, you are more likely to develop blind pimples than those with dry skin.
Nodules are a type of hard pimple that can be large and painful. They form when an infected skin pore or follicle is located deep below the skin surface. Cysts are found deep below the skin when a pus-filled membrane forms around the infection. They are likely to scar.
Dr Murad recommends spot treating emerging pimples with salicylic acid. “It is a great anti-inflammatory ingredient, which is able to penetrate the pores, calm redness, reduce swelling, it also kills bacteria and exfoliates the skin's surface to speed up healing,” shares Dr Murad.
There's no evidence that hydrogen peroxide can safely and effectively cure acne. In reality, hydrogen peroxide may actually increase scarring on the skin by interfering with the wound-healing process. It can also cause skin irritation and burns if used at too high of a concentration.
If you have an hour to tackle your pimple
Icing the bump can help reduce inflammation and prevent it from getting any bigger. “Use an antibiotic cream or some tea tree oil on top of the acne, use an acne patch (the small round stickers to cover acne) and then conceal it with makeup.