It's true that using retinol on your hair and scalp can potentially result in some unwanted side effects. Ironically, the most serious side effect of retinol that was reported on several years ago was actually hair loss.
Minoxidil enhances hair growth by prolonging the anagen phase and induces new hair growth in androgenetic alopecia (AGA), whereas retinol significantly improves scalp skin condition and promotes hair growth.
This retinoid-associated alopecia is dose-dependent and hair loss is reversible after significant reduction of retinoid dose or cessation of the systemic therapy (Gupta et al., 1989; Murray et al., 1991; Berth-Jones and Hutchinson, 1995; Katz et al., 1999).
Tretinoin for Hair Loss — The Science
In this study from the Journal of Investigative Dermatology on the effects of oral retin a — oral tretinoin — on human scalp hair follicles, research showed that exposure to retinoic acid induced premature hair follicle regression.
There are definitely side effects with both retinols and retinoids, but I want to emphasize that they're temporary, lasting around three to four weeks. The most common side effects I see with patients are redness, dry and scaly skin and itching or burning.
Who should skip retinol? “Retinols can be a beneficial addition for most skin types, but it isn't a one-size-fits-all approach,” Panzica says. Board certified dermatologist Zenovia Gabriel, MD, notes that “people with sensitive skin conditions like rosacea cannot tolerate really strong topicals like retinols.”
Topical all-trans-retinoic acid (tretinoin) alone and in combination with 0.5% minoxidil has been tested for the promotion of hair growth in 56 subjects with androgenetic alopecia. After 1 year, the combination of topical tretinoin with 0.5% minoxidil resulted in terminal hair regrowth in 66% of the subjects studied.
If the reason for thinning hair is genetics, it will not grow back on its own. To grow back a healthy, full head of hair, you'll need to take action, and that involves reviewing different hair loss options.
Consuming too much vitamin A over a long period of time can cause coarse hair, partial loss of hair (including the eyebrows), cracked lips, and dry, rough skin. Chronic consumption of large doses of vitamin A can cause liver damage. It can also cause birth defects in a fetus.
The hair loss is likely temporary, and your hair should start growing back when you stop taking the medication. You can also take certain steps to prevent or limit hair loss caused by isotretinoin. Preventive steps can include avoiding the sun, increasing your folate intake, moisturizing, and adjusting your dosage.
“Topical retinoids, those used for anti-aging, may cause eyebrow hair loss,” Bossavy warns. That doesn't mean you need to give up your precious retinol products — just keep them off your arches. “Don't apply your retinoid to your eyebrow or the area immediately above, where it may migrate,” the pro suggests.
It could potentially reduce DHT production.
As mentioned above, retinol reduces excess surface oil on the scalp and also on the follicles. In doing so, Dr. Shainhouse shares retinol “may help to reduce DHT production. DHT is associated with genetic-type male/female-patterned hair loss.”
It's Hormonal Or Medical
"Sudden thinning hair can be a symptom of anemia (low red blood cell count), hormonal issues especially related to events like pregnancy, or a thyroid disorder, which are all very common in women," says Peredo. If any of these are the case, hair loss won't be the only symptom present.
Minoxidil (Rogaine) is approved by the FDA for female pattern hair loss. It can slow or stop it in most women and may help hair grow back. But the benefits go away when you stop using it. Corticosteroids can help regrow hair for women with alopecia areata.
Retinyl palmitate also strengthens the scalp by improving cell turnover, boosting collagen production to create the best conditions for hair to grow. At the same time, it can be used on sensitive scalps without irritation (we use a concentration of 0.5%).
Retinoids reduce fine lines and wrinkles by increasing the production of collagen. They also stimulate the production of new blood vessels in the skin, which improves skin color. Additional benefits include fading age spots and softening rough patches of skin.
Retinoids work best if you use them daily. Specifically, they should be used at night because some types are deactivated by light and air. It's important to start slowly and allow your skin time to adjust. Using too much too quickly can cause redness, dryness, and irritation.
Retinol significantly decreased both hormone levels, however retinoic acid decreased the progesterone level only. In the second part of the experiments adolescent rats (in the 6th and 7th week after birth) were treated and measured similar to the newborns.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
Generally speaking, I recommend most people start using retinol in their mid to late-20s, anywhere from 25-30. This is when collagen and elastin production starts to slow down, so it's the perfect time to start reaping the preventative-aging benefits retinol has to offer.
Hyaluronic acid is best if they're looking to moisturize dry skin, while retinol works better by encouraging better skin by boosting collagen production. They have several benefits that can work in tandem for better results, though patients need to be careful with the exact formulations they use.
Tretinoin is known to alter cell proliferation and differentiation and may promote vascular proliferation, and these actions may be important to hair growth and so affect hair follicle during the various growth and regression phases.
For example, Accutane may affect the hair shafts and follicles themselves. Most of the time, any hair loss is temporary, and the thin hair should start to thicken again with time. However, some people may notice a permanent change in their hair after taking isotretinoin.