Alopecia areata (AA), an autoimmune disease that causes hair loss, including baldness, has been linked to a significantly increased risk for dementia, new research shows.
Androgenic alopecia (AGA) is associated with significant cardiovascular risk factors that also have a negative impact on brain aging.
Background: Alopecia areata (AA) is associated with multiple comorbidities and shares a similar inflammatory signature with dementia. The great negative psychosocial impact of AA may result in poor social engagement, a typical risk factor for dementia.
Alopecia can have serious psychosocial consequences, causing intense emotional suffering, and personal, social and work-related problems. Surveys have shown that around 40 per cent of women with alopecia have had marital problems, and around 63 per cent claimed to have career-related problems (Hunt & McHale, 2004).
Alopecia areata primarily affects hair, but in some cases, there are nail changes as well.
Answer: Alopecia areata and fatigue and cold intolerance
Suppression of adrenal gland function can lead to both fatigue and cold intolerance for example.
Compared with the general population, increased prevalence rates of psychiatric disorders are associated with alopecia (Koo et al., 1994) suggesting that people with alopecia may be at higher risk for development of a major depressive episode, anxiety disorder, social phobia or paranoid disorder.
Alopecia areata is not medically disabling; persons with alopecia areata are usually in excellent health. But emotionally, this disease can be challenging, especially for those with extensive hair loss.
If you have alopecia areata, it generally doesn't cause pain or other symptoms. However, some people say that right before they lose their hair, they feel tingling, itching, or burning on the skin where the hair will fall out.
Alopecia areata can occur at any age but about half of cases come on in childhood and 80% of cases come on before the age of 40 years. Men and women are equally affected. The condition tends to be milder if it comes on at an older age.
Alopecia areata is not life-threatening and does not cause physical pain. However, the psychosocial effects of hair loss can be devastating. In addition, patients may experience symptoms related to hair loss, such as increased eye or nasal irritation after loss of eyelash or nasal hair.
Hair loss (alopecia) can affect just your scalp or your entire body, and it can be temporary or permanent. It can be the result of heredity, hormonal changes, medical conditions or a normal part of aging. Anyone can lose hair on their head, but it's more common in men.
This type of baldness is not usually caused by a disease. It is related to aging, heredity, and changes in the hormone testosterone. Inherited, or pattern baldness, affects many more men than women. Male pattern baldness can occur at any time after puberty.
Often, hair grows back within several months, even without treatment. It may grow in fine or white at first, but usually returns to its original texture and color with time. People with alopecia areata may lose and grow back their hair more than once, either in the same patches as before or in different patches.
Because hair loss and regrowth from alopecia areata is unpredictable and sometimes cyclical (comes back again and again), having the condition can be frustrating and emotionally challenging for many people.
Alopecia areata (AA) is a chronic autoimmune inflammatory disease characterized by hair loss that can affect the scalp, face (e.g. eyebrows and eyelashes) and body .
How does alopecia areata affect daily life? For many people, hair is an important part of their appearance and self-image, and any type of hair loss can lower self-esteem and confidence. In alopecia areata, the unpredictable cycle of hair loss and regrowth can make the symptoms even more difficult to cope with.
Loss of self-confidence, lowered self-esteem, and heightened self-consciousness are common responses to hair loss, particularly for women. People with alopecia are more likely to develop depression and anxiety.
The condition is not covered by any legislation designed to combat disability discrimination such as the Americans with Disabilities Act in the U.S. or the Equality Act in the U.K.
The inheritance pattern of alopecia areata is unclear because multiple genetic and environmental factors appear to be involved. Overall, the risk of developing the condition is greater for first-degree relatives (such as siblings or children) of affected individuals than it is in the general population.
Alopecia areata is a common autoimmune skin disease, causing hair loss on the scalp, face and sometimes on other areas of the body. In fact, it affects as many as 6.8 million people in the U.S. with a lifetime risk of 2.1%. People of all ages, both sexes and all ethnic groups can develop alopecia areata.
Alopecia areata is sometimes triggered by viral infections such as influenza that causes excess production of interferons (IFN). IFN- γ is one of the key factors that lead to the collapse of immune privilege.
A variety of factors are thought to cause alopecia areata (al-o-PEE-she-uh ar-e-A-tuh), possibly including severe stress. With alopecia areata, the body's immune system attacks the hair follicles — causing hair loss.
“Alopecia Areata itself does not compromise the immune system or cause immune deficiency and there is no reason to think that people with Alopecia Areata are more at risk from COVID-19 than the general population, either in terms of catching the virus or being more severely affected by it.