Retinol and tretinoin are both retinoids, which means they are compounds that come from vitamin A. They're both commonly used in topical creams to treat a number of skin conditions. Though they're similar, tretinoin is more concentrated than retinol.
Tretinoin and Retinol Have Different Strengths
As the stronger substance, tretinoin is a more effective substance when treating conditions such as acne and is an ideal choice for those with oily or highly-tolerant skin. It also has substantial anti-wrinkle properties.
Retinol is like the training wheels for tretinoin and other dermatology-grade retinoids. They have similar benefits and can be used on any skin type, though tretinoin is more often recommended to treat acne and is FDA approved for photoaging. Tretinoin is the more potent of the two, so it will show results faster.
Retinol, has been shown to improve the appearance of photodamaged skin when applied topically, and is generally considered to be approximately ten times less potent than tretinoin.
Yes, you can use tretinoin every night, but you may not want to at first—and some people may never want to. Tretinoin can cause skin irritation and peeling, especially when you first start using it.
"You can use tretinoin or [over-the-counter] retinols forever."
After 4-6 weeks, your skin will get used to tretinoin and will begin to be noticeably smoother and more even. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.
Tretinoin It is a derivative of Vitamin A acid and is an effective slow bleaching agent that can be safely used in the eye area in an emollient cream base.
If you stop using the medication or are inconsistent with your treatment, any improvements you see may disappear over time. Always use the product as prescribed by your healthcare provider (Rodan, 2016).
Technically, retinol and Retin-A do the same thing. But retinol is much weaker than Retin-A because it first has to be converted into retinoic acid in order to be used by the skin. Retin-A is retinoic acid, so it can be used directly by the skin as soon as it's applied.
In addition, several over-the-counter products containing retinoids, such as retinol, are available. Because they're not as strong (and thus less irritating), they are not as effective in reducing wrinkles as tretinoin; but they do improve the appearance of photo-aged skin.
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Avoid using other medications on the areas you treat with tretinoin topical unless your doctor tells you to.
On average, it takes eight to 24 weeks of treatment for tretinoin to produce noticeable improvements in wrinkles and other signs of aging. One short study published in the Journal of Cosmetic Dermatology, which used a . 025 percent tretinoin cream, found a “statistically significant improvement” after just 84 days.
Tretinoin Does Not “Bleach” Your Skin
Contrary to popular belief, tretinoin is not a “bleaching agent” or medicine designed specifically to lighten your skin tone. While tretinoin can even out patches of hyperpigmentation and cause a mild change in your skin tone, it doesn't affect melanin synthesis.
You may notice tretinoin starting to work within 2 to 3 weeks, but it can take 6 weeks or more to experience the full benefit. If you don't see improvement within 12 weeks, or if you have significant improvement and wonder if you should start using it less frequently, talk to your doctor.
Tretinoin is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. Tretinoin is classified as a "retinoid." (For more detail, see "How Tretinoin Works" section below).
Tretinoin was shown to stimulate some hair regrowth in approximately 58% of the subjects studied.
Commonly reported side effects of tretinoin include: pleural effusion, dyspnea, edema, fever, hypotension, leukocytosis, weight gain, headache, hypercholesterolemia, hypertriglyceridemia, increased liver enzymes, nausea, visual disturbance, and vomiting.
Use just a pea-sized portion.
This is enough for your face. Dab a bit from this portion onto your forehead, cheeks, and chin, then smooth it around. Use another pea-sized portion for your neck or chest if you need to apply in those areas, too.
Topical creams
Tretinoin (Retin-A) is widely used to fight the signs of aging because it stimulates the production of new skin. There are also many antiaging moisturizers that are similarly effective. They may help reduce the appearance of fine lines around the eyes, but will not improve deep crow's feet.
Do not use this medicine in or around the eyes or lips, or inside of the nose. Spread the medicine away from these areas when applying.
Tretinoin can help dark spots fade, allowing you to have a more even skin tone. It decreases the amount of melanin in your skin cells (Zasada, 2019). When used for discoloration, tretinoin is usually combined with other skin-lightening products, sometimes in the form of a chemical peel (Lawrence, 2021).
Tretinoin gel, cream, or lotion requires a prescription because it's more powerful than retinol. Doctors prescribe tretinoin to treat skin conditions like: Acne. Psoriasis.
In the morning, wash your face with a mild facial scrub or rough washcloth. This will help reduce the noticeable flaking. After washing, apply a good water-based moisturizer. The moisturizer will make the drying effect of the medicine more tolerable.
Does Retin-A (tretinoin) help reverse skin aging? Yes. Retin-A, whose active ingredient is tretinoin, has been shown to have positive effects on both the deeper collagen layers of your skin as well as the upper most layer that is comprised of skin cells.