Do dermatologists recommend niacinamide?

Author: Kody Green  |  Last update: Saturday, December 13, 2025

I typically recommend the topical form of this ingredient for three main skin concerns, including anti-aging, uneven skin tone, and oiliness and large pores.”

Who should not apply niacinamide?

Gallbladder disease: Niacinamide might make gallbladder disease worse. Kidney dialysis: Taking niacinamide seems to increase the risk of low platelet levels in people with kidney failure who are on dialysis. Stomach or intestinal ulcers: Niacinamide might make ulcers worse.

Which is better for skin, vitamin C or niacinamide?

Pick a secondary concern: To make a choice, zero in on a secondary skin concern. So, if you want to brighten with oil control – try Niacinamide. To ensure brightening while fighting fine lines, wrinkles and more – we recommend using Vitamin C for the skin.

Do I really need niacinamide?

Niacinamide is a form of vitamin B3 or niacin, an essential nutrient that provides many health benefits to your skin, kidneys, heart, nerves, gut, brain, and other body organs.

Which is better, hyaluronic acid or niacinamide?

For those struggling with acne, inflammation, or excess oil production, niacinamide may be the better option. On the other hand, if your primary concern is dryness, dehydration, or aging skin, hyaluronic acid could be the way to go.

Everything you need to know about anti-aging powerhouse Niacinamide!

Is it OK to mix hyaluronic acid and niacinamide together?

Both have been praised for their remarkable benefits in improving skin texture, hydration, and overall complexion. The increased popularity of these ingredients has left many with a pressing question: Can you use niacinamide and hyaluronic acid together? The short answer: Yes!

Is niacinamide or retinol better?

Retinol is usually more effective than niacinamide. The adverse side effects of retinol are not present in niacinamide. From a molecular standpoint, retinol mainly penetrates the skin's outer layer. Niacinamide can permeate the skin more deeply than retinol, mainly when made with soy components.

What should you not mix with niacinamide?

DON'T MIX: AHA/BHA and niacinamide

Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.

What are the disadvantages of niacinamide on face?

What are the side effects of Niacinamide? Topical application is completely safe and may not cause any skin problems for a healthy person. People with sensitive skin may face mild redness, itching, or a burning sensation. Stomach upset.

What are the only four skincare ingredients that have been proven to work?

These are retinoids, vitamin C, niacinamide and alpha hydroxy acids (AHAs). Whereas ingredients such as hyaluronic acid temporarily plump and smooth the skin, some of the big 4 may have longer-term health benefits.

Is 10% niacinamide too much?

For general skin tone correction, a niacinamide concentration between 4-5% is often effective and well-tolerated by most individuals. For those looking to tackle more pronounced hyperpigmentation, a higher concentration of 10% may be beneficial, though it's important to monitor the skin for any signs of irritation.

Why can't you use vitamin C and niacinamide together?

The misconception that you shouldn't use niacinamide and vitamin C together originates from outdated studies conducted in the 1960s. These early studies suggested that combining these ingredients could render them ineffective or cause skin irritation due to the instability of vitamin C in certain formulations.

Can I use niacinamide every day?

It's an ingredient found in a number of moisturizing skin-care products as well as in certain foods and supplements like multivitamins. Can you use niacinamide every day? Yes. In fact, you can use niacinamide-containing topical products in the morning and night because it's generally a gentle ingredient.

Why do some people not like niacinamide?

How do you know if niacinamide is not for you? You might find that niacinamide isn't for you if you experience side effects like redness, itching, or irritation after using it. Some people may also have an allergic reaction, resulting in hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Why is my skin getting darker after using niacinamide serum?

Some may also have skin discoloration due to using niacinamide combined with other active ingredients that are too harsh for your skin type. Niacinamide can also cause problems when it's mixed with the following substances: Acids, including lactic acid, glycolic acid, and azelaic acid.

What is the best combination with niacinamide?

Niacinamide + salicylic acid is what you need in your skincare routine. Salicylic acid is best known for its deep-cleansing properties and deep-penetrating action to unclog pores and slough off dead and dry skin. The antibacterial and anti-inflammatory properties of salicylic acid help clear away pustules and papules.

Who should avoid niacinamide?

Niacin and niacinamide may make allergies worse by increasing histamine. People with low blood pressure should not take niacin or niacinamide because they may cause a dangerous drop in blood pressure.

Does niacinamide cause weight gain?

The present study also showed that nicotinamide supplementation was associated with a dose-dependent increase in oxidative tissue injury. This may account for why high doses of nicotinamide do not promote weight gain (see Fig. 7(a) and Shibata et al.

What is the best niacinamide for the face?

Our Top Picks
  • Best Overall: Sunday Riley Be Nice 10% Niacinamide Serum, $65.
  • Best for a Glow: Glow Recipe Watermelon Glow Niacinamide Hue Drops, $35.
  • Best Affordable: The Ordinary Niacinamide 10% + Zinc 1% Oil Control Serum, $20.
  • Best Spot Treatment: Dr. ...
  • Best for Hyperpigmentation: La Roche-Posay Mela B3 Serum, $34.

What cancels out niacinamide?

Niacinamide and vitamin C

This combination sparks a lot of debate among skincare experts. Some say that since both niacinamide and vitamin C contain antioxidants, they cancel each other out and might even lead to irritation.

What reacts badly with niacinamide?

Though all skin types can benefit from niacinamide, Dr. Li warns that "combining niacinamide with vitamin C, also known as ascorbic acid, makes niacin, and may cause skin irritation and transient flushing." For this reason, Dr.

Do and don'ts niacinamide?

Don't use it with exfoliating ingredients: Niacinamide can increase skin sensitivity, so it's best to avoid using it with exfoliating ingredients such as salicylic acid and glycolic acid. Don't use it if you have an allergy: Niacinamide, like any other skincare ingredient, can cause allergic reactions in some people.

Is it OK to use retinol and niacinamide together?

So, if you're wondering 'can I use niacinamide with retinol? ', the simple answer is yes. Niacinamide and retinol have a synergistic relationship, so you can use them together as long as you're familiar with the basics of how to layer serums and ingredients.

Which is better for dark spots, niacinamide or vitamin C?

Both ingredients can fade hyperpigmentation and increase collagen production. Vitamin C (depending on the percentage) can be more harsh for sensitive skin types. Or, you might want to use niacinamide if you have acne-prone skin, and leverage Vitamin C for fading post-acne marks and dark spots.

Is niacinamide good for wrinkles?

Results: Analyses of the data revealed a variety of significant skin appearance improvement effects for topical niacinamide: reductions in fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness (yellowing). In addition, elasticity (as measured via cutometry) was improved.

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