Can you use vitamin C cream with glycolic acid?

Author: Mrs. Gregoria Boehm III  |  Last update: Saturday, April 26, 2025

CAN YOU USE BOTH GLYCOLIC ACID AND VITAMIN C? While both glycolic acid and vitamin C are skincare superstars, using them together requires a bit of caution, and it's generally not recommended to use them at the same time. If you're not sure about your routine, it's best to avoid using them in unison.

Can vitamin C be used with glycolic acid?

Using glycolic acid and vitamin C together can have a massive, positive effect on your skin — if done in the right way. Applying your glycolic acid product first to clear the skin, followed by your vitamin C product, means that both products can be as effective as possible.

What should you not mix with glycolic acid?

What NOT to mix with Glycolic Acid. Retinol, other AHAs/BHAs, Vitamin C: Using these ingredients alongside Glycolic Acid in the same routine could irritate the skin.

What shouldn't you mix with vitamin C?

Skincare ingredients not to mix with vitamin C

Vitamin C, AHAs (glycolic acid), and BHAs (salicylic acid) are acidic in nature. Layering them together can lower the skin's pH, making it more acidic. When skin pH goes off balance, it becomes a recipe for skin irritation, redness, and peeling.

Can I use vitamin C the morning after glycolic acid?

It's best to avoid combining glycolic acid (or lactic acid) and vitamin C in the same skin care session if you have a more sensitive skin type. For optimal results and to minimize potential irritation, utilize these powerful ingredients in separate sessions, establishing a separated AM & PM skin care approach.

Why I No Longer Use GLYCOLIC ACID - Glycolic Acid Explored

What should you avoid after glycolic acid?

Because Glycolic Acid exfoliates the top layer of the skin, we would recommend avoiding any other products that also promote skin cell turnover. This would include ingredients such as Retinoids and Copper Peptides. Combining multiple resurfacing products may increase the chances of developing skin sensitivities.

Which is better for hyperpigmentation, vitamin C or glycolic acid?

Yes, but glycolic acid is better for normal to dry skin, while vitamin C works well for all skin types, especially those prone to dullness or pigmentation.

What doesn't pair well with vitamin C?

Mixing the types of hydroxy acids known as BHA and AHA and vitamin C tends to be too much for the skin, resulting in discomfort or unwanted side effects.

What cancels out vitamin C?

Vitamin C + Niacinamide

However, when you combine niacinamide with Vitamin C, they'll cancel each other out chemically, making both formulas ineffective on your skin. Niacinamide takes out all the good properties of Vitamin C and makes it into a substance that can cause redness and trigger breakouts.

What is vitamin C not compatible with?

Vitamin C is effectively an acid (it's sometimes known as ascorbic acid), so layering it with AHAs and BHAs like glycolic, salicylic, and lactic acids is a big no-no.

What cancels out glycolic acid?

Glycolic acid and niacinamide.

Indeed, niacinamide used with AHA's like glycolic acid and lactic acid has no effect and can even cause redness. Since niacinamide has a pH of about 5-7, it can actually increase the lower pH of glycolic acid, which is about 3-4, and negate its properties.

What pairs well with glycolic acid?

Apply vitamin C in the morning and glycolic acid at night. Glycolic acid and hyaluronic acid: Since hyaluronic acid loads up skin with moisture, it makes for an excellent pairing with glycolic acid. Look for a product that combines both for easiest application, though you can also layer serums.

What should not be used with vitamin C serum?

Don't Mix with Certain Ingredients:

Avoid applying Vitamin C with products containing AHAs, BHAs, retinol, or benzoyl peroxide in the same routine. These ingredients have different pH levels that can clash with vitamin C, reducing its effectiveness and potentially causing irritation.

Is it better to use glycolic acid at night or morning?

As for whether you should apply glycolic acid morning or night, we recommend applying it as part of your evening skincare routine. Glycolic acid can cause “photosensitivity,” which means it makes your skin more sensitive to the sun's UV rays, upping your chances of a sunburn or skin damage.

Can I use glycolic acid and vitamin C and niacinamide together?

Using these two ingredients together at the same time can cause redness and itchiness on your skin. Does this mean you can't include niacinamide and glycolic acid in your skincare routine? No, you most definitely can!

Which serums cannot be used together?

Skincare ingredients not to mix
  • Retinoids or retinol and benzoyl peroxide. ...
  • Retinoids or retinol and vitamin C. ...
  • Retinoids or retinol and salicylic acid. ...
  • Retinoid or retinol and AHAs/BHAs. ...
  • Vitamin C and AHAs/BHAs. ...
  • Vitamin C and benzoyl peroxide. ...
  • Niacinamide and AHAs / BHAs. ...
  • Benzoyl peroxide and hydroquinone.

How to use glycolic acid and vitamin C together?

USE THEM AT DIFFERENT TIMES

By alternating between the two ingredients, you remove the risk of skin irritation. Apply glycolic acid to cleanse the skin of impurities, makeup and oil buildup from the day. Apply vitamin C in the morning to protect against free radicals throughout the day.

What reacts badly with vitamin C?

Possible interactions include: Aluminum. Taking vitamin C can increase your absorption of aluminum from medications containing aluminum, such as phosphate binders. This can be harmful for people with kidney problems.

What not to use with glycolic acid?

What NOT to mix with Glycolic Acid. Retinol, other AHAs/BHAs, Vitamin C: Using these ingredients alongside Glycolic Acid in the same routine could irritate the skin. However, alternating them between your morning and evening skincare routine means that you can enjoy the benefits without the risk of damaging your skin.

What is the best combination with vitamin C?

Additionally, vitamin C blocks abnormal production of pigmentation to even skin tone and fade dark spots. While it's best known for brightening, it can also be instrumental in skin firming. Vitamin C works best in combination with vitamin E, ferulic Acid, vitamin B, and hyaluronic acid.

What are the enemies of vitamin C?

Anyway, heat and water are the enemies of vitamin C in potatoes, as they are in all vegetables. Vitamin C is soluble in water, and too long an exposure to heat causes nutrients to vanish. Minimise the time, temperature and amount of water.

What should be avoided with vitamin C?

4 Skincare Ingredients to Avoid Mixing With Vitamin C
  • Retinol. Retinol and retinoids should not be mixed with vitamin C for a number of reasons. ...
  • Alpha Hydroxy Acids. ...
  • Beta Hydroxy Acids. ...
  • Benzoyl Peroxide.

Do you put vitamin C or glycolic acid first?

What's the best way to combine vitamin C and AHAs? For best results, Dr. Lee suggests exfoliating your skin before using vitamin C. Try using glycolic acid at night (to minimize its photosensitizing tendencies), followed by vitamin C in the morning (to maximize its antioxidant potential).

Which acid is best for removing dark spots?

The American Academy of Dermatology (AAD) recommends the following treatments for dark spots in skin of color:
  • azelaic acid.
  • glycolic acid.
  • kojic acid.
  • retinoids, such as retinol, tretinoin, adapalene gel, or tazarotene.
  • vitamin C.

What can I mix with vitamin C for hyperpigmentation?

Mixing ceramides and vitamin C enhances their overlapping skin benefits. They include boosting skin hydration, reducing the appearance of fine lines and wrinkles, protecting against UV ray damage, encouraging healthy cellular turnover and reducing hyperpigmentation.

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