Conclusions. Based on our findings, vitamin D levels were significantly low in patients with vitiligo in comparison with controls; however, we did not observe any significant effect of vitamin D on the occurrence and extension of vitiligo lesions.
In summary, the present study suggests that, at least for patients with autoimmune disorders like vitiligo and psoriasis, a daily dose of 35,000 IU of vitamin D is a safe and effective therapeutic approach for reducing disease activity.
Vitamin B12 has been shown to be useful for repigmentation in patients suffering from vitiligo. Folic acid (or vitamin B9) has been proven to be significant for treating vitiligo. It needs to be included in the diet as the body cannot synthesize it.
Vitiligo is a common pigmentary disorder caused by the destruction of functional melanocytes. Vitamin D is an essential hormone synthesized in the skin and is responsible for skin pigmentation. Low levels of vitamin D have been observed in vitiligo patients and in patients with other autoimmune diseases.
A 2018 review suggests various natural remedies, including ginkgo biloba, green tea, and aloe vera, may improve vitiligo symptoms. However, more research is necessary to determine their safety and effectiveness. People should speak with a doctor before trying natural remedies to ensure they are safe.
Vitamin B12 and Folic Acid
This is why it is always recommended to take these two vitamins together in order to treat vitiligo. According to some scientific studies, a combination of vitamin B12 and folic acid supplementation and sun exposure is a good strategy to regain natural skin color.
Wheatgrass Juice: Perfect for those with vitiligo and weak immunity. If you get sick easily when the weather changes, this juice is for you. Bottle Gourd Juice: Fresh and small bottle gourds are very helpful for white spots.
Young et al. found that melanin has a small inhibitory effect on vitamin D synthesis (21). Moreover, in vitiligo where we have a destruction of functional melanocytes it has been found that the application of vitamin D might help in preventing the destruction of melanocytes.
It can occur anywhere on the body. Most commonly vitiligo affects the skin around the eyes, mouth, elbows, wrists, hands and ankles. The condition can sometimes involve large areas of skin, but it is rare for people to lose all of their skin pigment.
It may be related to: A disorder of the immune system (autoimmune condition) Family history (heredity) A trigger event, such as stress, severe sunburn or skin trauma, such as contact with a chemical.
No drug can stop the process of vitiligo — the loss of pigment cells (melanocytes). But some drugs, used alone, in combination or with light therapy, can help restore some color. Drugs that control inflammation. Applying a corticosteroid cream to affected skin might return color.
Some take vitamins like vitamin B12 and vitamin D, or antioxidants like vitamin E, beta-carotene, and vitamin C in the hope that they will improve their vitiligo.
Treatment and follow-up Patients were given tablets containing vitamin B12 (1 mg cyanocobala- mine) and folic acid (5 mg) to be taken twice daily for 3 months. They were also encouraged to expose their skin to the sun in summer and UVB irradiation in winter, to induce a slight reddening of the white areas.
Topical steroids come as a cream or ointment you apply to your skin. They can sometimes stop the spread of the white patches and may restore some of your original skin colour. A topical steroid may be prescribed to adults if: you have non-segmental vitiligo on less than 10% of your body.
When vitamin D is taken orally, it is incorporated into the chylomicron fraction, and about 80% of the dose is absorbed into the lymphatics. The blood level of 25(OH)D will peak about 12 hours after a single dose of 50,000 IU.
Although vitamin D is essential for skin health, its primary role is the promotion of melanin formation, which may cause more skin darkening.
Vitiligo occurs when immune cells destroy the cells that make brown pigment (melanocytes). This destruction is thought to be due to an autoimmune problem. An autoimmune disorder occurs when the body's immune system, which normally protects the body from infection, attacks and destroys healthy body tissue instead.
It can appear at any age, but it often starts before the age of 20. The disease does not affect life expectancy.
Abstract. Vitiligo is a common pigmentary disorder caused by the destruction of functional melanocytes. Vitamin D is an essential hormone synthesized in the skin and is responsible for skin pigmentation. Low levels of vitamin D have been observed in vitiligo patients and in patients with other autoimmune diseases.
Can you take vitamin D3 without K2? Yes. The only real consideration to keep in mind is taking vitamin D3 without taking any vitamin K, because if you have a high level of vitamin D3 without enough vitamin K, the calcium might not transfer to the bones properly and instead end up in the vascular tissue.
Citrus fruits
Including Vitamin C-rich fruits like oranges, lemons, grapefruits, etc., in your diet is thus considered a healthy choice if you suffer from vitiligo. Vitamin C is crucial for collagen synthesis and acts as an antioxidant, helping to neutralise free radicals that can harm melanocytes.
Treatment cannot cure vitiligo.
While researchers are looking for a cure, treatment cannot currently cure this disease. Treatment can help restore lost skin color, but the color (repigmentation) may fade over time. To keep their results, many patients have maintenance treatments.