Can I use salicylic acid and niacinamide and hyaluronic acid together?

Author: Dr. Kailey Renner  |  Last update: Tuesday, September 16, 2025

As for using salicylic acid with hyaluronic acid and niacinamide the best way of applying the all effectively is starting with a exfoliating toner containing salicylic acid, followed with hyaluronic acid to hydrate and prevent skin irritation, then finally niacinamide to regulate the production of sebum of the skin.

What goes first, niacinamide or salicylic acid?

Salicylic Acid cleanser should always come first, then Niacinamide 10%. Be careful though because Salicylic Acid allows any active ingredients to penetrate deep to the skin.

Do you use hyaluronic acid before or after salicylic acid?

Comments Section rule of thumb = water based > oil based products. so in your case, it would be salicylic acid first, then hyaluronic acid, then moisturise. You should ideally leave an acid to 'sit' on the skin for about 20 minutes as to not mess with the pH.

What shouldn't you mix with salicylic acid?

Retinoids or retinol and salicylic acid

Generally, it's recommended you don't mix retinol and salicylic acid in your skincare routine due to the risk of redness or potentially irritating side effects [3].

What comes first, niacinamide or hyaluronic acid?

When used together, always go with applying hyaluronic acid first, followed by Niacinamide. By following this, you would be able to attract plenty of hydration first. After that, apply Niacinamide to help regulate sebum production and help with the minimization of pores.

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Can I use hyaluronic acid with niacinamide and salicylic acid?

As for using salicylic acid with hyaluronic acid and niacinamide the best way of applying the all effectively is starting with a exfoliating toner containing salicylic acid, followed with hyaluronic acid to hydrate and prevent skin irritation, then finally niacinamide to regulate the production of sebum of the skin.

What not to mix with niacinamide?

DON'T MIX: AHA/BHA and niacinamide

Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.

What is best paired with salicylic acid?

Salicylic Acid, the Right Combinations.
  • Zinc: Derived from beetroot, this trace element naturally present in the body is optimal for treating all types of skin imperfections. ...
  • The hydrosol of Centifolia Rose: ...
  • Benzoyl Peroxide: ...
  • Niacinamide: ...
  • Retinol:

Why is my skin getting worse after using salicylic acid?

If you've recently started using a product containing retinoids or chemical exfoliants such as glycolic or salicylic acid, there's a good chance your skin is feeling the purge. These ingredients work quicker by helping bring impurities to the surface and small red bumps can actually be a sign the product is working.

Can I use salicylic acid and niacinamide together every day?

Active ingredients are best used in regulation and lower concentration. It's important to check the compatibility of each ingredient while using them together. While it is safe to use niacinamide and salicylic acid together, it's better to use one in the morning and the second in the night routine.

How long to wait between hyaluronic acid and niacinamide?

Hyaluronic acid serums are usually lightweight and absorb quickly, so you don't need to wait longer than a minute or two to apply a niacinamide cream. If both products are thick or sticky, wait until the skin absorbs the first layer to avoid mixing and diluting the products.

Which is better, niacinamide or salicylic acid?

Skin Type Suitability: Salicylic acid is particularly effective for oily and acne-prone skin due to its ability to penetrate and clean out pores. Niacinamide, on the other hand, is suitable for all skin types, including sensitive and dry skin, due to its gentle and soothing properties. 3.

Should I moisturize right after salicylic acid?

Salicylic acid can be drying to the skin, so it's important to moisturize your skin after using it. Look for a moisturizer that is lightweight, non-comedogenic, and free of fragrances and other irritants. Moisturizing after using salicylic acid can help to soothe the skin and prevent dryness and irritation.

Which is first, salicylic acid or hyaluronic acid?

Using hyaluronic acid and salicylic acid. Hyaluronic acid can help rehydrate complexions after a chemical exfoliant like salicylic acid has been applied. This means you can support skin texture and clarity with salicylic acid, followed by hyaluronic acid to nourish and soften the skin.

Should I use niacinamide in the morning or night?

4. When should I apply niacinamide? Niacinamide can also be used morning and/or night, but as it's an antioxidant and can help to control oil and treat breakouts (invisibly!), it is well-suited to a morning routine (just avoid layering it with vitamin C as the two can make each other unstable).

How long does it take for salicylic acid and niacinamide to work?

How long does Niacinamide take to work? Using 5% or 10% Niacinamide-containing products show better effects with no skin problems like irritation. Most studies show that even though you may find improvement immediately after starting Niacinamide, it usually takes anywhere between 8-12 weeks for a visible change.

What does salicylic acid purging look like?

When purging your skin, you'll typically see blackheads and small, flesh-coloured bumps rather than inflamed pustules, nodules or deeper cysts. But this is not an absolute rule. Overall, acne caused by skin purging often tends to appear and then disappear much faster than classic breakouts.

Does niacinamide cause tiny bumps?

Does niacinamide cause pimples? Niacinamide does not cause any pimples as it is gentle on most people of all skin types. But it might irritate if it is used in larger quantities.

Can salicylic acid and hyaluronic acid be used together?

In short, yes — you absolutely can use salicylic acid and hyaluronic acid together. These two ingredients complement each other, and, when used in tandem, can contribute to a healthy, radiant complexion.

What is a bad combination for salicylic acid?

Salicylic Acid + Glycolic Acid

Mixing the two together will strip your skin and most likely cause irritation. Using these acids together can also over exfoliate the skin, which can actually speed up the aging process because it slows cell turnover.

What should you not mix with niacinamide?

Many skincare experts believe it best to avoid mixing vitamin C with niacinamide. This is a topic that creates a lot of debate amongst skincare, and you may find it confusing which one to believe.

What order should I do my skincare?

The right morning routine will help your skin feel calm and hydrated all day long.
  1. Step 1: Cleanser. A clean face is your starting point for a healthy, glowing complexion. ...
  2. Step 2: Toner. ...
  3. Step 3: Serum. ...
  4. Step 4: Moisturizer. ...
  5. Step 5: Eye Cream. ...
  6. Step 6: Sunscreen.

How to use niacinamide and salicylic acid together?

Salicylic acid and niacinamide complement each other and can provide synergistic results when used together. After you cleanse your skin, apply a salicylic acid product. Then, follow that with niacinamide, and finish by moisturizing and adding sun protection.

What reacts badly with niacinamide?

Niacinamide works well with other skincare ingredients, including retinol and hyaluronic acid. However, some ingredients, like vitamin C, may interact negatively with niacinamide. Therefore, it's recommended to use products containing these ingredients at different times of the day or on alternate days.

What pairs well with salicylic acid?

For an enhanced skincare regimen, you can pair your salicylic acid serum with the following active ingredients:
  • Hyaluronic acid serum and salicylic acid serum. ...
  • Niacinamide serum and salicylic acid serum. ...
  • Alpha arbutin serum and salicylic acid serum.

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