Yes, you can use both glycolic acid and niacinamide in your regular skincare routine – in fact, there are products that include both of these multi-tasking ingredients in a single formulation.
Niacinamide goes after both glycolic acid and vitamin c since those are pH-dependent actives.
Niacinamide generally works well with most products, but it's best not to combine it with vitamin C (ascorbic acid) in the same routine as it can cause irritation. Additionally, avoid using it with strong exfoliants or retinoids in high concentrations to prevent skin sensitivity. For more, check out my Quora Profile.
What NOT to mix with Glycolic Acid. Retinol, other AHAs/BHAs, Vitamin C: Using these ingredients alongside Glycolic Acid in the same routine could irritate the skin.
Glycolic acid and niacinamide.
The layering of these ingredients is counterproductive. Indeed, niacinamide used with AHA's like glycolic acid and lactic acid has no effect and can even cause redness.
There are several active ingredients that can be paired together and are beneficial for your skin. However, glycolic acid and niacinamide cannot be used together at the same time. This is because mixing these two ingredients can make these acids less effective.
Apply vitamin C in the morning and glycolic acid at night. Glycolic acid and hyaluronic acid: Since hyaluronic acid loads up skin with moisture, it makes for an excellent pairing with glycolic acid. Look for a product that combines both for easiest application, though you can also layer serums.
Combining glycolic acid and lactic acid can be quite potent and is generally not recommended due to the increased risk of irritation. Both acids are effective exfoliants, and using them together can over-exfoliate the skin.
Retinoids and Glycolic Acid
Retinoids (including retinol) are fantastic for boosting cell turnover and fighting aging. However, pairing them with glycolic acid is like inviting two energetic party crashers into a small room—they can overwhelm your skin.
Niacinamide and vitamin C
This combination sparks a lot of debate among skincare experts. Some say that since both niacinamide and vitamin C contain antioxidants, they cancel each other out and might even lead to irritation.
Niacinamide works well with other skincare ingredients, including retinol and hyaluronic acid. However, some ingredients, like vitamin C, may interact negatively with niacinamide. Therefore, it's recommended to use products containing these ingredients at different times of the day or on alternate days.
Niacinamide + salicylic acid is what you need in your skincare routine. Salicylic acid is best known for its deep-cleansing properties and deep-penetrating action to unclog pores and slough off dead and dry skin. The antibacterial and anti-inflammatory properties of salicylic acid help clear away pustules and papules.
Hydrate and moisturise: Use hydrating products like serums or moisturisers after using glycolic acid. These aid in rehydrating and nourishing the skin. Look for products that contain hydrating ingredients like hyaluronic acid, ceramides, or natural oils to help maintain a healthy skin barrier.
It's an ingredient found in a number of moisturizing skin-care products as well as in certain foods and supplements like multivitamins. Can you use niacinamide every day? Yes. In fact, you can use niacinamide-containing topical products in the morning and night because it's generally a gentle ingredient.
Glycolic Acid
It is an alpha-hydroxy acid (AHA) derived from sugarcane. In low concentrations, glycolic acid produces desquamation of pigmented skin cells. About 30 to 70 per cent of glycolic acid can enhance the penetration of other skin lighteners such as HQ.
Don't mix: Vitamin C should not be used with retinol products as this can cause irritation. Additionally, vitamin C should not be mixed with niacinamide since the effectiveness of vitamin C will be decreased. As mentioned above vitamin C should not be mixed with AHAs or BHAs, or benzoyl peroxide products.
Don't use vitamin C: Niacinamide and vitamin C can cause skin irritation and discoloration when used together, so it's best to use them at different times of the day. Don't overuse: While niacinamide is generally well-tolerated, overusing it can cause redness and irritation, especially in people with sensitive skin.
Retinol and Benzoyl Peroxide
It is useless to use benzoyl peroxide, which is usually used to treat acne, and retinol together, says Paviol. The ingredients can cancel the positive effects of each other out and leave skin extremely dry and irritated.
It is said that your skin needs some time between each ingredient that you apply to let it completely absorbed into the skin to make it work efficiently. We can safely say that niacinamide and glycolic acid can work if you choose to use these together but after a gap of at least 30 minutes.
What NOT to mix with Glycolic Acid. Retinol, other AHAs/BHAs, Vitamin C: Using these ingredients alongside Glycolic Acid in the same routine could irritate the skin. However, alternating them between your morning and evening skincare routine means that you can enjoy the benefits without the risk of damaging your skin.
Otherwise, a good way to incorporate retinol into your beauty routine in addition to glycolic acid would be to alternate them every other night: one night using retinol, another night using a no-rinse exfoliating treatment followed by a moisturizing cream.
Hyaluronic Acid acts a humectant by pulling moisture into your skin, making it ideal to use with Glycolic Acid, which can be drying or irritating at times. You can opt to layer Hyaluronic Acid over Glycolic Acid or use Hyaluronic Acid in the morning and Glycolic Acid in the evening.
Bear in mind that you can have more than one Niacinamide product in your skincare routine. After cleaning and drying your skin, you can apply a Niacinamide toner, then a Niacinamide serum, or a face cream. What we emphasise most is the order of layering of the product.
More irritation does not mean better results. You know your skin best and if you feel any discomfort, rinse off. Though gentle enough for everyday use, we generally recommend to exfoliate once or twice a week.