Can I mix vitamin C and E together?

Author: Dovie Treutel  |  Last update: Sunday, April 6, 2025

Vitamins may also act synergistically when used in combination [8]. Some studies suggest the importance of combining topical vitamins C and E to protect the skin against UV irradiation and maximize photoprotection [9,10].

Can I use vitamin E and vitamin C together?

Yes, you can take Vitamin E and Vitamin C together. They work synergistically as antioxidants, enhancing each other's effects. For best absorption, take them with meals and avoid excessive doses to prevent side effects.

Which should I apply first, vitamin C or E?

Ideal layering techniques for effective results: The ideal routine is to first apply your vitamin C antioxidant serum after cleansing and toning. Let it fully absorb, then follow with a vitamin E serum or moisturiser to seal the benefits. You can also mix a few drops of vitamin E oil into your vitamin C serum.

What not to mix with vitamin E?

View interaction reports for vitamin e and the medicines listed below.
  • Aspirin Low Strength (aspirin)
  • Benadryl (diphenhydramine)
  • Calcium 600 D (calcium / vitamin d)
  • CoQ10 (ubiquinone)
  • Crestor (rosuvastatin)
  • Cymbalta (duloxetine)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • Flonase (fluticasone nasal)

Is vitamin E and C a good combination?

In summary, taking vitamin E and vitamin C together is generally safe and may offer potential health benefits, especially when it comes to their antioxidant properties.

Skincare Ingredients You CAN'T Mix?! | Doctorly Investigates

What does vitamin C and E do to your body?

Here, vitamin E serves as the primary defense against potentially harmful oxidation reactions (NRC, 1989). In addition to vitamin E, ascorbic acid (vitamin C) is one of the other essential nutrients, assisting in this antioxidant defense system by protecting against lipid peroxidation (Frei et al., 1988).

What is the best combination with vitamin E?

Vitamin E (400 IU) combined with other antioxidants, including zinc (80 mg), beta-carotene (15mg), and vitamin C (500 mg), seems to protect against developing age-related macular degeneration (AMD). AMD is the leading cause of legal blindness in people over 55 in the United States.

Why should you not take vitamin E everyday?

The risk of side effects increases with higher doses. Side effects can include nausea, fatigue, headache, and bleeding. Vitamin E is possibly unsafe when taken in doses greater than 1000 mg daily.

Why avoid taking vitamin C at night?

Unlike fat-soluble vitamins, it doesn't require food or specific timing to work effectively. However, some people may want to avoid taking it before bed: If you have acid reflux or a sensitive stomach – Vitamin C, especially in high doses, can increase stomach acidity, and lead to mild heartburn or nausea.

Can I take collagen, vitamin C, and vitamin E together?

There's no recorded evidence proving that taking collagen and vitamins together has a negative impact or creates health concerns.

Can I use vitamin C and E at night?

Even if you don't have sensitive skin, we recommend that all skin types use their vitamin C serum before bed. Your body undergoes its natural repair process while you're asleep, and the vitamin C will make its strongest impact on your skin during this time.

What should you not mix with vitamin C serum?

Beta Hydroxy Acids

So that salicylic acid of yours should not be mixed with your vitamin C serum. It won't be able to help you with discoloration, collagen production, or protect you from UV rays. Additionally, combining the two can cause irritation and dryness.

What are the side effects of vitamin C and E capsules?

In some cases, Vitamin C+vitamin E may cause side effects like headache, nausea, heartburn, diarrhoea, and fatigue. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Can you have too much vitamin C and E?

Vitamin C is considered to be a very well-tolerated vitamin because if your body can get rid of it through the urine if has too much. Because your body stores vitamins A and E, having too much of these vitamins can cause health problems.

What are the symptoms of a vitamin E deficiency?

Patients presenting early may show hyporeflexia, decreased night vision, loss/decreased vibratory sense; however, they have normal cognition. A more moderate stage of this deficiency may show limb and truncal ataxia, profuse muscle weakness, and limited upward gaze.

Is 1000mg of vitamin C too much?

If you're an adult, limit yourself to no more than 2,000 milligrams (mg) of vitamin C a day. The recommended upper limit for children varies by age.

What does vitamin E do for the body?

Vitamin E helps maintain healthy skin and eyes, and strengthen the body's natural defence against illness and infection (the immune system).

Is vitamin C better at night or morning?

While you can work your vitamin C serum into either your morning or evening skincare routine, most dermatologists recommend the morning [2]. This keeps your skin protected from free radicals as you go about your day, and can work especially well with your sunscreen to keep you safe from UV radiation.

What to avoid when taking vitamin E?

Interactions
  • Alkylating agents and antitumor antibiotics. ...
  • Anticoagulant and antiplatelet medicines, herbs, and supplements. ...
  • Cytochrome P450 3A4 substrates, also called CYP3A4 substrates. ...
  • Statins and niacin. ...
  • Vitamin K. Taking vitamin E with vitamin K might keep vitamin K from working as it should.

Is it OK to use vitamin C and E together?

Vitamin C is great for skin. So is vitamin E. Put them together, and you've created something truly extraordinary. This “better together” pairing of two super-antioxidants is supported by decades of scientific research demonstrating how their interaction improves antioxidant performance to deliver visible results.

What vitamins not to take at night?

6 supplements you should not take at night!
  • Vitamins B.
  • Multivitamins and energy herbs.
  • Vitamin D.
  • Calcium.
  • Vitamin C.
  • Zinc.

Does vitamin E remove dark spots?

Does vitamin E remove dark spots? Vitamin E doesn't remove dark spots on its own, but through its role as an antioxidant, it can prevent oxidative stress than can lead to discolorations (7). However, as we've said many times, skin care is much more nuanced than just relying on the power of a single ingredient.

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