Will I break out if I stop using tretinoin?

Author: Rosie Koepp  |  Last update: Saturday, May 31, 2025

For many, tretinoin is highly effective at treating acne, but it's still possible to experience breakouts once you stop using it. Even while using tretinoin, you may continue to experience breakouts from time to time (we're looking at you, hormonal acne!), but that's also completely normal.

Do you have to keep using tretinoin forever?

According to Dr. Mohta, to maintain the benefits you achieved over the past year, it is crucial to continue using tretinoin as part of your long-term skincare routine. You can safely use tretinoin long-term. Research has shown no negative effects even with 2-4 years of usage.

What happens if you suddenly stop using tretinoin?

It may take 3 to 4 months or up to 6 months before you notice improvement. If you stop using tretinoin, the improvement may gradually disappear.

Does skin go back to normal after tretinoin?

“The symptoms related to tretinoin purging typically involve acne breakouts, severe skin dryness and peeling, redness and irritation, but it is important to know that this phase is temporary and once it's over, the skin will generally begin to improve, and you will be able to see the positive effects.

How long does tretinoin make you break out?

During the first 3 weeks you are using tretinoin, your skin may become irritated. Also, your acne may seem to get worse before it gets better. It may take longer than 12 weeks before you notice full improvement of your acne, even if you use the medicine every day.

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Will I get acne again if I stop using tretinoin?

For many, tretinoin is highly effective at treating acne, but it's still possible to experience breakouts once you stop using it. Even while using tretinoin, you may continue to experience breakouts from time to time (we're looking at you, hormonal acne!), but that's also completely normal.

What does tretinoin purge look like?

Skin purging is common, but doesn't necessarily happen to everyone. In fact some people don't experience it at all. For those of us who do suffer from purging, it can look like: breaking out in pustules (pimples), the appearance of flaky, peeling skin, irritation and dry patches.

Is tretinoin 3 times a week enough?

You should aim to use tretinoin every night, however, you must start slowly as your skin needs to get used to it. The first 2 weeks apply it 2 to 3 nights per week, after that try applying it every other day, and then if your skin can handle it, apply it every night.

What is the downside of tretinoin?

Topical tretinoin can cause your skin to become dry, red, swollen, blistered, or flaky. It may also cause your skin to itch, be painful, or feel like it is burning. Stop using topical tretinoin and call your healthcare provider if these symptoms become worse or do not go away.

How do you maintain skin after tretinoin?

Moisturize. Using a water-based moisturizer after applying tretinoin is generally recommended. This can help protect your skin from some side effects of the treatment, including dryness, peeling, and irritation.

Will my acne come back if I stop using retinol?

Unfortunately, stopping treatment usually means a return of pimples. That's because most acne treatment medications don't cure acne but rather keep the symptoms under control.

Does tretinoin increase facial hair in females?

Dr Kiran acknowledges some evidence that suggests tretinoin may aid in hair growth: Tretinoin promotes cell turnover, which can help rejuvenate hair follicles. It may enhance the absorption of other hair growth treatments, such as minoxidil.

When should I give up on tretinoin?

Signs you should stop using tretinoin

“If your face is red, tender, or very parched and peeling, these are signs you're overusing your retinoid,” Dr. Ansell says—either you're applying too much, or too frequently.

Does tretinoin cause weight gain?

If you experience any of the following symptoms, call your doctor immediately: fever; weight gain; swelling of the arms, hands, feet, ankles, or lower legs; shortness of breath; labored breathing; wheezing; chest pain; or cough.

Is it OK to use tretinoin for years?

Renova and Retin-A are sometimes hailed as miracle products that promise youthful, blemish-free, smooth skin to anyone from the age of 15 through to 70. However long-term use of Tretinoin, the generic name for these products, does not come without long-term issues some of which are under-stated and rarely reported.

Does tretinoin thicken or thin skin?

Topical tretinoin stimulates epidermal proliferation and differentiation by upregulating heparin binding epidermal growth factor (HB-EGF), which causes increased exfoliation and thickening of the epidermis.

Is it bad to use tretinoin every night?

Schwartz suggests easing into it by using tretinoin every other night at first so that your skin can adapt to it and develop a tolerance. Then, if you and your doctor decide that you might need to use it more frequently, you can apply tretinoin daily.

Is tretinoin bad for the heart?

Treatment with this drug may lead to higher cholesterol and triglycerides. The effect of these changes on heart health is not known. Talk with the doctor.

Does tretinoin affect hair growth?

In conclusion, tretinoin has shown promise in promoting hair growth due to its ability to stimulate cell growth and enhance blood supply to hair follicles. While many have reported positive outcomes, it's essential to consult with a dermatologist to determine if it's the right option for you.

What is the sandwich method for tretinoin?

Option one: The sandwich technique

After washing your face, apply a layer of moisturiser. Allow it to dry down for 5-10 minutes. Then, apply a pea-sized amount of tretinoin to your entire face. Allow this to dry down for 5-10 minutes.

What moisturizer is best with tretinoin?

Three inexpensive moisturizers that our physicians love are Vanicream Daily Facial Lotion with Hyaluronic Acid, Neutrogena Hydroboost Gel, and The Ordinary Hyaluronic Acid Serum. All three of these are affordable, non-comedogenic,and blend well with tretinoin.

How to tell if tretinoin is working?

After 4-6 weeks, your skin will get used to Tretinoin and will begin to be noticeably smoother and more even. Depending on how often you use Tretinoin, you may begin to see full benefits by this point. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.

What are the tretinoin uglies?

Vitamin A can be unstable as an ingredient, and this can mean your skin will become more sensitive. There is often an initial phase when using retinoids for the first time, known by many as the 'retinoid uglies'. Essentially, your skin can see a decline before improvement during an adjustment period.

When do most people purge on tretinoin?

Purge & Progress (Weeks 2-8): This period can see an uptick in breakouts as Tretinoin accelerates cell turnover. While disheartening, this is temporary and normal. Your doctor can help you get through this by adjusting your protocol.

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