Why does my skin look worse on tretinoin?

Author: Lola Kerluke  |  Last update: Thursday, September 18, 2025

Any medication designed to combat acne by accelerating skin cell turnover, such as topical retinoids like tretinoin, can cause skin purging. ⁷ It's a temporary phase typically lasting a few weeks. Importantly, this is often considered a positive sign that your acne medication is working to clear dead skin cells.

Why does my skin look worse after using tretinoin?

Tretinoin purging: Tretinoin commonly causes a skin purge, characterized by acne breakouts, dryness, and irritation, especially when first used or when the dosage is increased.

How long does tretinoin purging last?

How long does a tretinoin purge last? Results will vary from person to person. The American Academy of Dermatology recommends waiting four to six weeks for any new skin care treatment to start clearing up skin. If you are experiencing purge symptoms after six weeks, talk to your provider.

How do you get rid of tretinoin uglies?

Myers believes that “gentle exfoliation is your best friend” and can help to remove some of the dry, flaky skin that may be irritating you. Try to use a natural exfoliant such as a product that contains coffee, sugar, or oatmeal. Just don't scrub at your skin too hard!

Why does my skin look worse after using retinol?

This is called retinol skin purging, and it's the stage where your skin may get worse before it gets better. It's alarming, especially if you're not a skincare expert or if it's your first time using the product. However, these symptoms are usually just the expected side effect of retinoids.

Not Seeing Results with Retin-A (TRETINOIN)? Watch This Before You Quit & Avoid My Biggest Mistake

What does a retinol purge look like?

For those of us who do suffer from purging, it can look like: breaking out in pustules (pimples), the appearance of flaky, peeling skin, irritation and dry patches. Getting these symptoms can be demotivating, especially if you're already feeling unconfident about your skin.

What moisturizer goes well with tretinoin?

Three inexpensive moisturizers that our physicians love are Vanicream Daily Facial Lotion with Hyaluronic Acid, Neutrogena Hydroboost Gel, and The Ordinary Hyaluronic Acid Serum. All three of these are affordable, non-comedogenic,and blend well with tretinoin.

How to know if tretinoin is working?

After 4-6 weeks, your skin will get used to Tretinoin and will begin to be noticeably smoother and more even. Depending on how often you use Tretinoin, you may begin to see full benefits by this point. A lot of the initial irritation will settle down and true “retinization” of your skin is in full force.

Does your face get worse before it gets better on tretinoin?

During the first 3 weeks you are using tretinoin, your skin may become irritated. Also, your acne may seem to get worse before it gets better. It may take longer than 12 weeks before you notice full improvement of your acne, even if you use the medicine every day.

How long does it take for skin to adjust to tretinoin?

Initial Adaptation:

The first 2-6 weeks of using Tretinoin generally involve your skin getting used to it.

Is tretinoin 3 times a week enough?

You should aim to use tretinoin every night, however, you must start slowly as your skin needs to get used to it. The first 2 weeks apply it 2 to 3 nights per week, after that try applying it every other day, and then if your skin can handle it, apply it every night.

Should you pop pimples during tretinoin purge?

It can be tempting to pop pimples as they form or pick away at dry skin, especially during a breakout. During the purge phase, it's best to leave your skin alone and allow it to heal naturally. Stay hydrated. In addition to the acne purge, the first few weeks of using tretinoin can involve dry and irritated skin.

What does Tret Purge look like?

You can't Google prescription retinoid journeys without coming across reports of the famous tretinoin purge: a period of red, inflamed skin often subjected to more breakouts than you had before.

Why am I breaking out so bad on tretinoin?

Skin irritation

Don't fret! This is normal and known as a skin purge or flare. Over time, both your acne and skin irritation should improve. Tretinoin-treated skin should be handled gently.

Why does tretinoin make me look older?

In fact, the skin isn't getting worse but the initial period of adjustment may include skin dryness, flaking or irritation makes it look rougher. This then makes the skin look more aged or tired. Potential for Long-term Damage: If you don't use Tretinoin properly then you can damage the skin under your eyes.

What is the downside of tretinoin?

Topical tretinoin can cause your skin to become dry, red, swollen, blistered, or flaky. It may also cause your skin to itch, be painful, or feel like it is burning. Stop using topical tretinoin and call your healthcare provider if these symptoms become worse or do not go away.

What happens if I put too much tretinoin on my face?

Applying excessive amounts of tretinoin onto the skin to make acne go away faster will not work. This can make the skin worse by causing extreme dryness, peeling, or redness. It may take up to six weeks of tretinoin treatment to see results. Make sure to use sunscreen, especially in the summertime.

Does tretinoin cause weight gain?

If you experience any of the following symptoms, call your doctor immediately: fever; weight gain; swelling of the arms, hands, feet, ankles, or lower legs; shortness of breath; labored breathing; wheezing; chest pain; or cough.

What is the best cleanser for tretinoin?

Wash face thoroughly with a mild soap or a gentle alcohol-free non-soap cleanser such as Neutrogena Fresh Foaming Wash, Cetaphil cleanser, or CeraVe cleanser.

What causes tretinoin to not work?

Inconsistent use will not produce results. Period. Retinoids are inactivated by UV light, so must be applied at night. Additionally, retinoids can be inactivated by other topical skin care ingredients, most commonly salicylic acid.

What is the sandwich method of tretinoin?

Option one: The sandwich technique

After washing your face, apply a layer of moisturiser. Allow it to dry down for 5-10 minutes. Then, apply a pea-sized amount of tretinoin to your entire face. Allow this to dry down for 5-10 minutes.

What's better, tretinoin or differin?

Both adapalene and tretinoin will effectively cure your acne and dark spots, although tretinoin is likely to produce results more quickly, but adapalene gel is less irritating for patients.

What not to mix with tretinoin?

You may also want to avoid salicylic acid, glycolic acid, and erythromycin gel (Erthygel), as these ingredients and products can cause dryness. Though, your dermatologist can help you decide if combining these products with tretinoin is safe. Tretinoin can also cause sun sensitivity.

Should you put tretinoin on your neck?

The skin on the neck is thinner and more sensitive, so it may not tolerate tretinoin well, causing irritation. However, if you want to address signs of ageing on your neck, you may benefit from using tretinoin there. To avoid irritation, start with a lower frequency on your neck and build up as your skin tolerates it.

Does tretinoin peeling ever stop?

Some people may notice that this side effect goes away within a few weeks of use, while others may have flaky skin for up to two months. Regardless of how long it takes to subside, tretinoin peeling is temporary and will go away once your skin gets used to the product.

Previous article
How to draw out a sebaceous cyst at home?
Next article
What causes lack of protein in hair?