Who shouldn't take hyaluronic acid supplements?

Author: Prof. Declan Flatley DVM  |  Last update: Monday, November 3, 2025

However, people who have a history of severe allergic reactions, such as anaphylaxis, should be cautious when using hyaluronic acid. Its effects during pregnancy and while breastfeeding remain unknown, so women may want to avoid taking hyaluronic acid supplements during these times.

Who should not take hyaluronic acid supplements?

Allergic reaction: If you are allergic to Hyaluronic Acid, you should avoid using products that contain it. Medical conditions: If you're experiencing a medical condition, such as diabetes or a bleeding disease, or if you are pregnant or nursing, you should see a doctor before taking Hyaluronic Acid.

Is there a downside to hyaluronic acid?

The most common adverse effects associated with hyaluronic acid filler are pain, bruising, redness, itching, and swelling. These side effects are self-limited and typically last no more than seven days.

Who can not use hyaluronic acid?

Allergic reactions might occur but are rare. Pregnancy: There isn't enough reliable information to know if hyaluronic acid is safe to use when pregnant. Stay on the safe side and avoid use. Breast-feeding: There isn't enough reliable information to know if hyaluronic acid is safe to use when breast-feeding.

Do hyaluronic acid supplements interact with any medications?

There are 14 drugs known to interact with hyaluronan, along with 1 disease interaction. Of the total drug interactions, 14 are moderate.

Most Don't Know This About Hyaluronic Acid

When should you avoid hyaluronic acid?

However, people who have a history of severe allergic reactions, such as anaphylaxis, should be cautious when using hyaluronic acid. Its effects during pregnancy and while breastfeeding remain unknown, so women may want to avoid taking hyaluronic acid supplements during these times.

What medications should you not take with collagen?

There are no well-known drug interactions and we don't yet know what the best dose of collagen is.

What should not be paired with hyaluronic acid?

Niacinamide and Salicylic Acid: Niacinamide is a popular skincare ingredient that can help minimize pores and improve skin texture. Salicylic acid, on the other hand, is often used to treat acne. While both ingredients have their own benefits, using them together with hyaluronic acid may cause irritation or dryness.

Is hyaluronic acid hard on the liver?

10. Is Hyaluronic Acid Bad For Your Liver? In the case of patients with liver diseases, it is advised to avoid using HA as the increased levels of HA in the bloodstream can cause thrombosis. Hence, user discretion and medical supervision are advised.

What are the side effects of taking hyaluronic acid?

Are there any side effects to using hyaluronic acid?
  • Bruising.
  • Sore injection site.
  • Swelling.
  • Formation of tiny, generally temporary bumps.

Does taking hyaluronic acid orally work?

Long-term use of hyaluronic acid serum on your skin or in a supplement taken by mouth can improve overall skin health. It's also great for helping improve overall skin flexibility and elasticity (meaning it makes your skin more stretchy and soft).

What does hyaluronic acid do to hair?

Hyaluronic Acid helps to seal the cuticle, locking in moisture and taming that unwanted frizz. Address Scalp Dryness - Scalp care is the key to overall health hair. As mentioned above, Hyaluronic Acid is an hydrating ingredient that does not only hydrate the hair, but the scalp too!

Can you overdo it with hyaluronic acid?

While hyaluronic acid is a great hydrator, overusing it can lead to dehydrated skin. This happens because hyaluronic acid can only attract and retain a limited amount of moisture, and using too much can cause it to pull moisture from deeper layers of the skin.

Does hyaluronic acid affect the kidneys?

Over the past 15 years, HA has been observed to induce varying effects in kidney injury and disease that largely depend on the study model but are considerably influenced by its MW. For example, Ito et al. showed that HMW-HA bound to CD44 promotes proximal tubular cell (PTC) migration in vitro via MAPK activation [41].

Why do people not like hyaluronic acid?

The alarming amount of miseducation around HA has also spearheaded a belief that it can be incorporated into ALL steps of your routine. But this excessive use can be the driver behind several skin woes like dryness, redness, and irritation.

What are the restrictions of hyaluronic acid?

You may receive between one and five injections, usually a week apart, depending on which brand of hyaluronic acid your healthcare professional uses. For at least two days after the injection, you should avoid jogging, high-impact sports or being overly active.

Does hyaluronic acid raise blood pressure?

Other reported side effects include: Pain. Fatigue. Increased blood pressure.

What are the complications of hyaluronic acid?

The most common complications are injection site reactions, including edema, pain, erythema, itching, and ecchymosis [14]. Other reported AEs are hypersensitivity reactions, infections, Tyndall effect, and surface irregularities and nodules [15-18].

Does hyaluronic acid increase inflammation?

Recent studies have shown that low-molecular-weight Hyaluronic acid (LMW-HA) exhibits proinflammatory effects, while high-molecular-weight Hyaluronic acid (HMW-HA) functions as an anti-inflammatory factor.

Does hyaluronic acid interact with other medications?

Hyaluronic Acid can interact with various drugs, altering its efficacy or increasing the risk of adverse effects. Notable Drug Interactions: 1. Hormonal Contraceptives: Hyaluronic Acid can reduce the effectiveness of birth control pills.

Can you use vitamin A and hyaluronic acid together?

Hyaluronic acid and vitamin A work in synergy to help you achieve radiant, plump and youthful-looking skin. Vitamin A helps to improve the appearance of fine lines, wrinkles and encourages collagen production, while hyaluronic acid compliments vitamin A's benefits by visibly plumping, smoothing and firming the skin.

What not to mix with peptides?

For that reason, mixing peptides and glycolic acid is not recommended. Why shouldn't these acids be mixed with peptides? The reason peptides and salicylic acid as well as peptides and glycolic acid aren't efficacious ingredient combinations is because peptides are susceptible to hydrolysis when exposed to acids.

Who cannot take collagen supplements?

Collagen supplements may not be safe for:
  • People with fish, shellfish, or egg allergies (collagen supplements may contain these allergens as ingredients)22.
  • People with a Kosher or Halal diet.
  • People with a vegetarian or vegan diet.

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