Who should not use hyaluronic acid?

Author: Mrs. Maye Reichert MD  |  Last update: Wednesday, November 12, 2025

Hardening of skin and connective tissue (scleroderma): Applying hyaluronic acid to the skin might make skin ulcers worse in people who have a condition called scleroderma. If you have scleroderma, don't use hyaluronic acid on your skin.

Who shouldn't take hyaluronic acid?

However, people who have a history of severe allergic reactions, such as anaphylaxis, should be cautious when using hyaluronic acid. Its effects during pregnancy and while breastfeeding remain unknown, so women may want to avoid taking hyaluronic acid supplements during these times.

Are there any bad side effects to hyaluronic acid?

Hyaluronic Acid is generally considered safe, although some people may experience side effects such as swelling, redness, and itching at the injection site. In rare cases, Hyaluronic acid injections can cause an allergic reaction, which can cause severe swelling and difficulty breathing.

What should you not pair hyaluronic acid with?

What Not to Mix with Hyaluronic Acid: Expert Advice for Your Skincare Routine
  • Retinol and Hyaluronic Acid: A Powerful Combination. ...
  • However, there are certain ingredients that should not be mixed with hyaluronic acid: ...
  • Step 1: Cleansing. ...
  • Step 2: Toner/Mist. ...
  • Step 3: Antioxidant Serum. ...
  • Step 4: Moisturizer. ...
  • Step 5: Sunscreen.

What medications does hyaluronic acid interact with?

Medications known to interact with hyaluronan
  • benzalkonium chloride topical.
  • cetylpyridinium topical.
  • COVID-19 mRNA (Moderna) vaccine.
  • COVID-19 mRNA (Pfizer) vaccine.
  • sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 308)
  • sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 309)
  • sars-cov-2 (covid-19) mrna-lnp vaccine (cvx 310)

Demi Moore’s Ageless Glow at 61: Her Anti Aging Skincare and Health Routines Revealed and Analyzed!

What is better for your face, retinol or hyaluronic acid?

Indeed, retinol is excellent for treating acne and imperfections, while hyaluronic acid is ideal for dehydrated skin. And it is also possible to combine them in your beauty routine to benefit from their full effectiveness. This moisturizing cream, to be used daily, has many advantages!

Is hyaluronic acid hard on the liver?

10. Is Hyaluronic Acid Bad For Your Liver? In the case of patients with liver diseases, it is advised to avoid using HA as the increased levels of HA in the bloodstream can cause thrombosis. Hence, user discretion and medical supervision are advised.

What happens if you use hyaluronic acid everyday?

What does hyaluronic acid do for skin? Long-term use of hyaluronic acid serum on your skin or in a supplement taken by mouth can improve overall skin health. It's also great for helping improve overall skin flexibility and elasticity (meaning it makes your skin more stretchy and soft).

What is the best hyaluronic acid for mature skin?

We chose OSEA Hyaluronic Sea Serum as the best for mature skin because of its impressive ability to deliver overnight hydration, leaving our skin looking fresh, plump, and radiant by morning. Mature skin often requires intense moisture to maintain elasticity and minimize fine lines, and this serum excels at both.

Is hyaluronic acid safe for kidneys?

AH results from HA specifically accumulating in glomerular afferent and efferent arterioles. This increased renal HA accumulation has been linked to worsened proteinuria, faster loss of kidney function, and increased cardiovascular events.

Which face serum is best?

  • Vitamin C Daily Glow Face Serum With Vitamin C & Turmeric for Radiant Skin - 30 ml. ...
  • Skin Correct Face Serum with Niacinamide and Ginger Extract for Acne Marks and Scars - 30 ml. ...
  • Vitamin C Daily Glow Face Serum 10 ml. ...
  • Rice Water Dewy Active Serum With Rice Water & 10% Niacinamide For Glass Skin - 50 ml.

What are the cons of hyaluronic acid serum?

Are there any side effects to using hyaluronic acid?
  • Bruising.
  • Sore injection site.
  • Swelling.
  • Formation of tiny, generally temporary bumps.

What happens if you put too much hyaluronic acid on your face?

But like all good things, moderation is crucial. Overloading your skin with HA can lead to the paradoxical drying effect or even irritation. Less is often more. Tune into your skin's needs.

Should you moisturize after hyaluronic acid?

Do moisturise after applying HA. Once you have applied your hyaluronic acid product, it is crucial to lock in the hydration with a moisturiser. Applying HA and not adding a layer of moisture on top can be detrimental to the skin as it can pull hydration from lower layers which will dehydrate skin further.

What should you not mix with hyaluronic acid?

For instance, Alpha Hydroxy Acids (AHAs), such as Lactic Acid and Glycolic Acid, and Synthetic Retinol are a pair that can easily cause irritation.

Is it better to use hyaluronic acid in the morning or at night?

Incorporating a hyaluronic acid serum into your skincare regimen is easy. This versatile ingredient can be used morning and night and works well with other formulations. As always, we recommend following the 3 core stages of a skincare regimen to layer your formulations.

Does hyaluronic acid have side effects?

Extremely rare side effects of hyaluronic acid gel injection include infection, tissue necrosis, granulomatous foreign body, and activation of herpes labialis.

Does hyaluronic acid affect your heart?

Hyaluronic acid binds water in the heart muscle and improves both the mechanical and electrophysiological functions of the heart. Thus, it was suggested that application of HA in the heart muscle after infarction could be a possible treatment 8.

Does hyaluronic acid turn into collagen?

These fillers are typically injected into the skin to reduce lines and wrinkles. They are thought to provide clinical improvement by adding volume to the skin, but researchers have found that cross-linked hyaluronic acid also stimulates production of new type I collagen in the dermis.

What are the complications of hyaluronic acid?

The most common complications are injection site reactions, including edema, pain, erythema, itching, and ecchymosis [14]. Other reported AEs are hypersensitivity reactions, infections, Tyndall effect, and surface irregularities and nodules [15-18].

What is the best moisturizer for aging skin?

SkinCeuticals' Triple Lipid Restore is our top pick because it absorbs well and promises deep hydration while providing skin a youthful glow. Glow Recipe Plum Plump Hyaluronic Cream is a close second because it can moisturize and plump skin intensely. Aging is a beautiful thing, but change isn't always easy.

Can you use vitamin A and hyaluronic acid together?

Hyaluronic acid and vitamin A work in synergy to help you achieve radiant, plump and youthful-looking skin. Vitamin A helps to improve the appearance of fine lines, wrinkles and encourages collagen production, while hyaluronic acid compliments vitamin A's benefits by visibly plumping, smoothing and firming the skin.

What does retinol burn look like?

The skin goes red, inflamed, and peeling because retinol has chemically burned away the upper layer of skin, the new exposed skin has not had enough time to build up its natural protection film to UV light and pollutants that a good UV moisturising oil can help with and reduce the exposure to skin cancer risk, ...

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