People with a history of liver disease, kidney disease, or stomach ulcers should not take niacin supplements. Those with diabetes or gallbladder disease should do so only under the close supervision of their doctors. Stop taking niacin or niacinamide at least 2 weeks before a scheduled surgery.
Gallbladder disease: Niacinamide might make gallbladder disease worse. Kidney dialysis: Taking niacinamide seems to increase the risk of low platelet levels in people with kidney failure who are on dialysis. Stomach or intestinal ulcers: Niacinamide might make ulcers worse.
If you take certain drugs to lower blood fats (bile acid-binding resins such as cholestyramine or colestipol), take niacinamide at least 4 to 6 hours before or after taking these medications. These products may bind with niacinamide, preventing its full absorption.
There have been a few reports of Niacinamide's adverse effects, including headaches, nausea, and stomach pain. Severe side effects of Niacinamide are rare but may occur with doses greater than 3 grams per day. These can include liver problems and high blood sugar levels.
People of all skin types can use niacinamide—from dry to oily or combination skin. To be sure it's safe, though, always apply niacinamide products to a test area of skin and observe for reactions. If you experience redness, itchiness, or further irritation, stop its use and consult a professional.
Safe but not totally for people with sensitive skin. As mentioned above, niacinamide seems to have an irritating effect when used with concentration formulas. Redness and itching are some of the common reactions. Although these are rare issues, they may still cause a great impact on someone's skin health.
DON'T MIX: AHA/BHA and niacinamide
Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.
How do you know if niacinamide is not for you? You might find that niacinamide isn't for you if you experience side effects like redness, itching, or irritation after using it. Some people may also have an allergic reaction, resulting in hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.
The present study also showed that nicotinamide supplementation was associated with a dose-dependent increase in oxidative tissue injury. This may account for why high doses of nicotinamide do not promote weight gain (see Fig. 7(a) and Shibata et al.
How often should you use niacinamide? For optimal benefits, we recommend using niacinamide either daily or twice a day. Whether you apply niacinamide once or twice a day will depend on your skin type, skin concerns and which other ingredients are contained within your morning and night routines.
Take for example Vitamin C and Niacinamide - two active ingredients we don't recommend using together in the same routine. The key word here is routine. You can use Niacinamide 10% + Zinc 1% in the AM routine and Ascorbyl Glucoside Solution 12% in the PM routine -- just not together in the morning or evening.
Zinc. Taking zinc with niacin might worsen niacin side effects, such as flushing and itching.
Niacinamide, a vitamin B3 derivative, is effective at reducing hyperpigmentation, capable of lightening dark spots significantly after several weeks' usage. Importantly, niacinamide is NOT a skin bleaching agent.
Ordinary niacinamide combined with an acid can cause a bad chemical reaction of redness and flushing. You'll want to leave at least 30 minutes between products or keep your niacinamide in the morning and your acids at night.
While animal products like fish, poultry, and meat have high amounts of niacin, you can obtain it from fruits like avocados and bananas, and other plant sources like mushrooms, whole grains, peanuts, potatoes, etc.
When used as part of a daily skincare routine, niacinamide may help calm the skin, reduce transepidermal water loss (TEWL), and increase hydration in the skin's uppermost layer. This makes niacinamide a beneficial skincare ingredient for those looking to promote hydrated, smooth, and even-toned skin.
Although topical niacinamide does not stimulate hair growth based on the existing body of evidence [17] , cosmetic formulations, including panthenol and niacinamide, significantly increase the diameters of individual thin hairs [19]. ...
Niacin treatment attenuates obesity-induced adipose tissue inflammation through increased adiponectin and anti-inflammatory cytokine expression and reduced pro-inflammatory cytokine expression in a niacin receptor-dependent manner.
What are the side effects of Niacinamide? Topical application is completely safe and may not cause any skin problems for a healthy person. People with sensitive skin may face mild redness, itching, or a burning sensation. Stomach upset.
There are potential side-effects of niacin therapy, including an uncomfortable flushing sensation, dermatitis (skin inflammation), heartburn, aggravation of peptic ulcers, increased blood sugar, increased panic and anxiety, and elevation of liver enzymes, which may indicate damage to liver cells.
Niacinamide has been shown to ease inflammation, which can help calm redness due to conditions like acne, rosacea and eczema. It can also soothe irritation caused by strong exfoliants like retinol or glycolic acid that remove dead cells from the surface of your skin.
For general skin tone correction, a niacinamide concentration between 4-5% is often effective and well-tolerated by most individuals. For those looking to tackle more pronounced hyperpigmentation, a higher concentration of 10% may be beneficial, though it's important to monitor the skin for any signs of irritation.
Though all skin types can benefit from niacinamide, Dr. Li warns that "combining niacinamide with vitamin C, also known as ascorbic acid, makes niacin, and may cause skin irritation and transient flushing." For this reason, Dr.
The misconception that you shouldn't use niacinamide and vitamin C together originates from outdated studies conducted in the 1960s. These early studies suggested that combining these ingredients could render them ineffective or cause skin irritation due to the instability of vitamin C in certain formulations.