Some people should steer clear of trying intermittent fasting: Children and teens under age 18. Women who are pregnant or breastfeeding. People with type 1 diabetes who take insulin.
Some evidence suggests that a 16-hour fasting, 8-hour eating cycle may raise heart disease risk compared with other time-restricted eating cycles. Intermittent fasting also may cause people to feel very tired and dizzy. It can affect diabetes management and cause headaches or mood swings.
Some people need to avoid intermittent fasting, including: People with eating disorders that involve restriction, such as anorexia or bulimia nervosa. People who take medications that require food intake or involve metabolic changes (such as diabetes) People who are pregnant or breastfeeding.
Potential Drawbacks of Intermittent Fasting
 If you're not already used to skipping meals or not eating for an extended period of time, the hunger and fatigue that can occur when starting IF can be difficult to handle. Other side effects can include insomnia, irritability, headaches, and nausea.
If fasting is impacting your emotions, decreasing your energy levels, or causing extreme hunger, it may be time to stop. Consult your healthcare provider if you are thinking about stopping intermittent fasting and/or looking for alternative options to achieve your weight loss goals.
However, some research shows this practice could possibly increase cardiovascular risks. "This recent study actually showed that those people practicing intermittent fasting are twice as likely of dying from heart disease or dying in general than those who don't practice this," explains Dr. Lopez-Jimenez.
People who follow intermittent fasting either skip their breakfast or dinner, but experts say if the choice is between breakfast or dinner, one should choose to skip the latter.
In conclusion, fasting impairs the urinary concentrating ability and, as a result, causes polyuria. This effect is mediated via suppression of AQP2 expression in the collecting duct.
A new study has found following an “early” time-restricted pattern where fasting runs from about 5:30 pm until about 10 a.m. the next morning helps improve blood sugar regulation and reduce abdominal subcutaneous fat amounts.
Fasting for 16 hours a day, leaving an 8-hour eating window, is called the 16:8 method or the Leangains diet. Some experts may recommend females fast for 14 hours and slowly build their way up to 16 hours, while males can start fasting for 16 hours straight away.
Unclear Long-Term Safety and Efficacy: The long-term safety and effectiveness of intermittent fasting are unsubstantiated. While some animal studies have shown improvements in certain health issues, these results don't necessarily translate to humans.
Do: Decide on your fasting-eating schedule and focus on nutritious, filling foods that will keep you sated for longer. Don't: Eat foods that are calorie-dense and nutritionally poor. They can make you feel even hungrier after fasting. Benefits: No counting carbs or calories.
You may need a longer or shorter eating window, or you may want to try out a new protocol entirely. Decrease (or increase) your calorie intake within your fasting window. Aim for 7–9 hours of sleep. Cut back on processed foods.
If you are fasting for weight loss or metabolic health, then coffee or even coffee with non-insulinogenic (insulin-spiking) additions like butter, coconut oil, or heavy cream should not break your fast. However, milk, flavored creamer, sugar, and many other sweeteners will break your fast, no matter your goals.
While both 12-hour and 16-hour fasting can promote fat burning, it's possible that a 16-hour fast may be more effective. This is because the longer fasting period may lead to a greater depletion of glycogen stores, which can trigger higher levels of fat burning.
If you are healthy and are not taking medication that affects your hydration, your kidneys should not be affected by careful fasting. Fasting can in the summer months be as long as 20 hours and some with underlying health conditions may not be able to fast for such long periods.
Organ Systems Involved
 The most immediate organ affected by a fast is the pancreas. During times of low plasma glucose, the pancreas will release more glucagon from the alpha cells found in the islets of Langerhans. Glucagon will mainly affect the liver as it stores most of the glycogen in the body.
Additionally, during fasting periods, since you're not eating, you may forget to drink water, promoting dehydration. Make sure to stay hydrated throughout your fasting periods, and monitor the color of your pee (urine) regularly. A pale yellow color is normal, whereas a dark color may indicate dehydration.
As much as IF is filled with benefits, there are mild side effects that can happen during fasting, which do not generally require medical or surgical treatment. Possible side effects can include dizziness, nausea, insomnia, headache, weakness, etc.
Pregnant women, young people, athletes and those with certain medical conditions. "Children who are in the growing stages and teenagers — they should not be doing intermittent fasting," says Dr Rouf. Nor should anyone who's very active, such as athletes, she adds.
This is called the metabolic switch, and research suggests that alternating between using glucose and ketones for energy — or eating and fasting — could be beneficial. Technically speaking, eating or drinking any calories breaks a fast.
Intermittent fasting meals plans should prioritize healthy foods such as fresh fruits and vegetables, legumes and whole grains, like rice and whole grain pasta. These foods are rich in fiber, vitamins and minerals that help to regulate blood sugar levels, which is important for managing hunger during fasting.
Men and women often experience an average weight loss of 1–2 pounds per week with intermittent fasting. That means you could lose 4–8 pounds in 30 days. Furthermore, studies show that typical weight loss with intermittent fasting is 7–11 pounds over the course of ten weeks.
An easy way to achieve this is to push dinner a little earlier or skip the late-night snacks. Healthy individuals may consider going longer (13 to 16 hours) to reap even greater benefits in terms of fat-burning.