Tretinoin is considered to be the most widely used prescription retinoid treatment for wrinkles. It comes in the form of a gel. During use, you must wear sunscreen daily to protect your skin from sunburn and photoaging.
Those with stubborn skin concerns, like deep wrinkles and pronounced uneven skin tone may want to consider a high percentage retinol cream, serum or treatment. But what percentage of retinol is effective? Look for formulations with a percentage between 0.3% and 1%, with retinol 1% being the strongest option.
Retinol increases skin cell production (proliferation). It helps unclog pores. Retinol also exfoliates your skin and increases collagen production, which can reduce the appearance of fine lines and wrinkles, giving your skin a fresher, plump appearance.
The difference between them is depth and speed! Retin-A penetrates immediately and into deeper layers of your skin to repair instantly. Retinol takes a while to penetrate and repair. They are both good quality anti-aging skin care products.
Hyaluronic acid is best if they're looking to moisturize dry skin, while retinol works better by encouraging better skin by boosting collagen production. They have several benefits that can work in tandem for better results, though patients need to be careful with the exact formulations they use.
While vitamin C is most notable for helping to brighten and improve hyperpigmentation, retinol is typically considered best-in-class for wrinkles and fine lines. And if you really want to give your skin a one-two punch to get noticeably healthier, you can certainly try incorporating both into your routine.
There is no doubt about it that retinol is significantly stronger than collagen. This is because retinol penetrates down deep into your skin, tricking your body into thinking it's younger than it is.
The good news is that it is never too late to start incorporating retinol into your skin care routine. People in the 60s and beyond have begun using retinol and still experienced results.
The Ordinary's Granactive Retinoid* 2% Emulsion ($9.80) is a retinoid active, part of the family of age-defiers that helps reduce wrinkles. While retinoids (a.k.a. a vitamin A derivatives) often get a bad rep for being irritating, The Ordinary's formula is designed to make the serum gentle while still being effective.
The strongest retinoids on the market are tazarotene 0.1% - either the cream of the gel. In most cases tazarotene 0.1% gel is the strongest- especially when it is used before a moisturizer.
However, it takes three to six months of regular use before improvements in wrinkles are apparent—and the best results take six to 12 months. Because retinoids can cause skin dryness and irritation, doctors often recommend using them only every other day at first and then gradually working up to nightly applications.
A 0.5-percent concentration is a good baseline.
For beginners, most dermatologists recommend a retinol with a concentration of 0.25 percent to one percent to see results. If your skin is not sensitive, you can usually tolerate something right in the middle; Dr.
If you're new to retinol, start off with a low dose of around 0.025%. If your skin has no adverse reactions, you can slowly move up to a higher percentage.
Advanced: 0.5% to 2%
But go there only if you absolutely must. Remember, the higher the dose, the higher the benefits, but also higher the risk of irritations. Even if your skin can tolerate retinol well by now, there's always the chance that pushing things too far will cause more problems than it's worth.
Best retinol for beginners
A good first retinol to try is this Neutrogena cream recommended by dermatologist Dr. Britt Craiglow.
First, the answer is yes, retinol can make wrinkles worse, especially when you first start using it. What is happening is a drying effect, and one can get epidermal sliding from separation from the dermis.
Don't Mix: Retinol with vitamin C, benzoyl peroxide, and AHA/BHA acids. AHA and BHA acids are exfoliating, which can dry out the skin and cause further irritation if your skincare routine already includes retinol.
There's no problem with using both retinol and vitamin C as part of your skincare routine, dermatologists say. In fact, Shirazi calls this combo a "power couple" when it comes to aging well.
“Vitamin C is a tough ingredient to formulate with because it's most effective in an acidic pH environment. Retinol works in a higher (more alkaline) pH. If using them together, they won't work optimally,” says Sikora.
Retinol stabilizes when combined with vitamin C, increasing its effectiveness. Vitamin C and Retinol form a protective barrier over the skin that fights skin damage and aging. This barrier does not mean you can layer the two, one on top of the other, because irritation and sensitivity may occur.