What to avoid while on Accutane?

Author: Dewitt Abernathy  |  Last update: Sunday, August 24, 2025

What may interact with this medication?
  • Alcohol.
  • Benzoyl peroxide, salicylic acid, or other drying medications used for acne.
  • Medications for seizures.
  • Orlistat.
  • Other medications that make you more sensitive to the sun such as sulfa medications.
  • Progestin-only birth control hormones.
  • St. John's Wort.

What foods should I avoid on Accutane?

Foods that cause rapid spikes in blood sugar, such as anything with high sugar content, potatoes, pasta, bananas, grapes, and candy should be avoided. Accutane can cause severe birth defects of the face, heart, or brain.

What products should you not take while on Accutane?

Cautions with other medicines
  • tetracycline antibiotics such as doxycycline, oxytetracycline, minocycline or lymecycline.
  • vitamin A or supplements containing vitamin A.
  • other acne medicines, including acne medicines applied to the skin (using both together may make skin irritation worse)

What chemicals should you avoid on Accutane?

Stop all skin care products that contain exfoliating acids such as salicylic acid and benzoyl peroxide. Once established on istotretinoin, topical retinoids (e.g. Adapalene or Epiduo) should also be stopped. Look for products that are non-comedogenic (non-pore blocking) and oil free.

What to avoid while taking isotretinoin?

do not breast-feed while you are taking isotretinoin and for 1 month after you stop taking isotretinoin. plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Isotretinoin may make your skin sensitive to sunlight.

Accutane | Roaccutane | Accutane Side Effects | Isotretinoin Helpful Tips

What you Cannot do while on Accutane?

In particular, people taking Accutane should avoid:
  • vitamin A supplements.
  • tetracycline antibiotics.
  • corticosteroids.
  • any other acne treatments.
  • alcohol (or keep it to a minimum)
  • phenytoin (Dilantin)
  • strong sunlight and sunbeds.
  • cosmetic skin procedures, such as waxing or laser treatment.

How long is Accutane purge?

How Long Does Purging Last on Accutane? While the duration can vary, purging typically lasts between four to six weeks after starting Accutane. However, individual experiences may differ based on skin type, acne severity, and dosage.

What should you stay away from on Accutane?

You should avoid certain supplements, especially those containing vitamin A. Accutane is a retinoid. Retinoids are effective acne medications that contain a form of vitamin A. Getting too much vitamin A can lead to toxicity, so it's best to avoid using other products that contain vitamin A while taking Accutane.

What does Accutane mess with?

Isotretinoin may cause bone or muscle problems, including joint pain, muscle pain or stiffness, or difficulty moving. You may get hurt more easily during rough sports.

Why can't you take Tylenol on Accutane?

Liver damage- Accutane is metabolized by liver just like alcohol and Tylenol so you should avoid these products during use. In addition, we monitor your liver early on to make sure there are no issues. Increased brain pressure- (AKA pseudotumor cerebri) can be a side effect of many medications including Accutane.

How to stay clear after Accutane?

Since Accutane does the heavy lifting, keep your routine simple: a gentle cleanser, a non-comedogenic moisturizer, and don't forget sunscreen.
  1. Step 1: Gently cleansing milk. ...
  2. Step 2: Non-comedogenic moisturizer. ...
  3. Ingredients to add to your routine. ...
  4. Don't forget your body's skin! ...
  5. A less rich cleanser and moisturizer.

Should I avoid dairy on Accutane?

Eat less processed food, eat more leafy greens, stay away from sugar & dairy products. If you are sensitive to gluten, don't eat it. Supplement your diet with elemental zinc or zinc sulfate.

What organ is Accutane bad for?

Accutane-Related Organ Problems

These symptoms could indicate damage to the liver, pancreas, bowel and esophagus. You should immediately inform your doctor of any of these symptoms. The damage might be permanent even after stopping Accutane, but swift treatment can increase your chances of recovery.

How to make Accutane work faster?

Take with food: Isotretinoin absorbs twice as well if you take it with meals. Isotretinoin is a lipophilic medication. One study showed 1.5-2 times greater absorption in the fed (large breakfast with 28 grams of fat) versus a fasting state.

What can you not drink on Accutane?

It's best not to drink alcohol while taking isotretinoin capsules, or at least keep the amount you drink to a minimum. This is because there's a risk of damage to your liver and that your cholesterol levels will increase.

Does Accutane make you gain weight?

Does Accutane Cause Weight Gain? A commonly prescribed medication for treating stubborn acne, there aren't significant studies pointing to weight gain as a side effect. Sometimes, people experience a decrease in appetite.

What should you not take with Accutane?

What may interact with this medication?
  • Alcohol.
  • Benzoyl peroxide, salicylic acid, or other drying medications used for acne.
  • Medications for seizures.
  • Orlistat.
  • Other medications that make you more sensitive to the sun such as sulfa medications.
  • Progestin-only birth control hormones.
  • St. John's Wort.

Can you lose weight on Accutane?

There may be a risk for latent diabetes related to insulin resistance, which is masked by Accutane treatment and no gain in weight. Some patients may even lose weight.

Can Accutane make you infertile?

There's no clear evidence to suggest that taking isotretinoin capsules reduces fertility in either men or women.

How do I get the best out of Accutane?

Accutane is soluble in fat but not water. This means that for Accutane to be properly absorbed, it must be taken simultaneously with fat. Otherwise less Accutane will be absorbed and there will be a much greater risk of recurrence of acne in the future.

Does Accutane cause vaginal dryness?

Sexual side effects

Speak to a doctor if you start having problems with sex such as erectile dysfunction (impotence), low sex drive (loss of libido), vaginal dryness, loss of feeling in your genitals or difficulty reaching orgasm. This can last a long time and can sometimes carry on after you stop taking isotretinoin.

Does Accutane remove acne scars?

If you're already dealing with established, stubborn acne scars, Accutane alone may not be the miracle solution to erase them entirely. It can certainly contribute to an overall improvement in skin texture and tone by preventing new acne scars, but it may not be sufficient to address existing scars.

Is Accutane worth it for mild acne?

Four to five months of Accutane treatment usually leads to clearing of acne. It is a potent medication that is very effective for nearly all types of breakouts. Accutane is needed for moderate to severe acne that has failed other treatments. It should be used for a severe, scarring acne.

Can you pop pimples on Accutane?

Papular acne is often managed with courses of oral antibiotics, to reduce redness and what's called inflammation in the skin, from antibiotics like doxycycline and minocycline to sulfa medications. Rule #1: do NOT pop pimples, which simply leads to increased risks of leaving scars.

How quickly do Accutane side effects start?

In the first 2 weeks, your skin will start to feel less oily. Before your first month of treatment ends, you may experience a paradoxical acne flare, termed colloquially as “Accutane purge.” Skin purging looks like acne exacerbation.

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