What should I not use with hyaluronic acid?

Author: Rebeca Stamm II  |  Last update: Monday, June 9, 2025

However, there are certain ingredients that should not be mixed with hyaluronic acid: AHAs and BHAs: AHAs (alpha hydroxy acids) and BHAs (beta hydroxy acids) are chemical exfoliants that can help improve skin texture and unclog pores.

What should you not mix with hyaluronic acid?

For instance, Alpha Hydroxy Acids (AHAs), such as Lactic Acid and Glycolic Acid, and Synthetic Retinol are a pair that can easily cause irritation.

What to avoid while using hyaluronic acid?

3 Hyaluronic Acid Mistakes To Avoid For Happy, Hydrated Skin
  • You're not applying hyaluronic acid to damp skin. It's easy to forget this rule but it's so! ...
  • You're not applying hyaluronic acid in the right order. ...
  • You're not following hyaluronic acid with an oil and/or moisturiser.

What does hyaluronic acid interact with?

Hyaluronic Acid and Derivatives have no noted serious interactions with any other drugs. Hyaluronic Acid and Derivatives have no noted severe interactions with any other drugs.

Does hyaluronic acid clash with anything?

Some active ingredients such as retinol and vitamin C can irritate the skin if used in conjunction with exfoliants such as acids, while more gentle humectants such as hyaluronic acid can make a harmonious pairing with just about everything.

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Is there a downside to hyaluronic acid?

The most common adverse effects associated with hyaluronic acid filler are pain, bruising, redness, itching, and swelling. These side effects are self-limited and typically last no more than seven days.

What compliments hyaluronic acid?

What Ingredients Does Hyaluronic Acid Pair Well With?
  • Vitamin C. Yes, these two superstars can give your skin a super anti-ageing boost with Hyaluronic Acid's plumping and hydrating qualities along with Vitamin C's antioxidant and brightening properties. ...
  • Ceramides. ...
  • Retinol. ...
  • Panthenol. ...
  • AHAs & BHAs.

When should you not use hyaluronic acid?

If you are receiving radiation therapy, don't use hyaluronic acid on your skin. Hardening of skin and connective tissue (scleroderma): Applying hyaluronic acid to the skin might make skin ulcers worse in people who have a condition called scleroderma. If you have scleroderma, don't use hyaluronic acid on your skin.

Which is the best combination with hyaluronic acid?

Hyaluronic acid and vitamin C is one of the best skincare pair that ensures superior skin health. These two ingredients compliment and complete each other when it comes to hydrating skin, and repairing signs of ageing.

What happens if you use too much hyaluronic acid?

Too many layers of HA can leave a film on the surface, blocking pores and potentially leading to breakouts. Less can truly be more—especially when it comes to HA.

Is hyaluronic acid hard on your liver?

10. Is Hyaluronic Acid Bad For Your Liver? In the case of patients with liver diseases, it is advised to avoid using HA as the increased levels of HA in the bloodstream can cause thrombosis. Hence, user discretion and medical supervision are advised.

Can I use vitamin C and hyaluronic acid together?

While vitamin C and hyaluronic acid can be used separately for impressive outcomes, they are also a power duo when applied in tandem. In fact, vitamin C and hyaluronic acid are often mixed - either in one serum formula, or layered in a skincare regime.

What are the precautions for hyaluronic acid?

Avoid activities such as jogging, soccer, tennis, heavy lifting, or standing on your feet for a long time. Temporary pain or swelling in the knee joint may occur after receiving hyaluronic acid injection. Call your doctor if the pain or swelling in the knee persists or becomes worse after receiving this medicine.

What is the rule of hyaluronic acid?

The Only Rule for Hyaluronic Acid? Always Apply It on Damp Skin! It might sound surprising, but when hyaluronic acid is applied to dry skin, it can have the opposite effect, leaving your skin even more dehydrated.

Which serums are not to use together?

PRODUCT COMBINATIONS THAT DON'T WORK TOGETHER
  • RETINOL SERUM + VITAMIN C. ...
  • RETINOL SERUM + AHAS/BHAS. ...
  • AHAS/BHAS + VITAMIN C. ...
  • NIACINAMIDE SERUM + VITAMIN C. ...
  • TRANEXAMIC ACID. ...
  • SALICYLIC ACID SCALP TREATMENT + GLYCOLIC ACID SCALP TREATMENT. ...
  • PRESCRIBED/OTHER ACTIVES TREATMENTS. ...
  • HYALURONIC ACID SERUM + RETINOL/AHAs/BHAs.

What do you layer hyaluronic acid with?

For even-looking skin, pair Vitamin C derivatives with Glycolic Acid. For smoother-looking skin, pair Retinaldehyde and Hyaluronic Acid. For clearer-looking skin, pair Salicylic Acid and Niacinamide 10% + Zinc 1%. For hydrated skin, pair Hyaluronic Acid and Niacinamide.

What not to pair with hyaluronic acid?

However, there are certain ingredients that should not be mixed with hyaluronic acid:
  • AHAs and BHAs: AHAs (alpha hydroxy acids) and BHAs (beta hydroxy acids) are chemical exfoliants that can help improve skin texture and unclog pores. ...
  • Benzoyl Peroxide: Benzoyl peroxide is a common ingredient found in acne treatments.

What is the best routine with hyaluronic acid?

Use a moisturizer containing hyaluronic acid twice daily to access the best effects. These products should be used after you have cleansed your skin. If your routine also includes applying serums and exfoliating, apply your moisturizer after these steps.

What should not be in a face wash?

Which chemicals in face wash are dangerous for skin? The most dangerous face wash chemicals include Sodium Lauryl Sulfate, fragrances with phthalates, Propylene Glycol, Paraffin, Mineral Oil, Butylene Glycol and Isopropyl Alcohol.

Should you use hyaluronic everyday?

Is the word “acid” making you think of ingredients like alpha-hydroxy acids and retinoic acid? Don't worry. Hyaluronic acid is acidic by name, but not by nature and won't exfoliate the skin or supercharge its turnover. For this reason, it's perfectly fine to use hyaluronic acid every day.

What are the restrictions of hyaluronic acid?

You may receive between one and five injections, usually a week apart, depending on which brand of hyaluronic acid your healthcare professional uses. For at least two days after the injection, you should avoid jogging, high-impact sports or being overly active.

Why is my face burning after hyaluronic acid?

Hyaluronic Acid is unlikely to cause burns. However, certain individuals may experience a stinging sensation triggered by allergies. You can avert this problem by starting with a lower concentration of Hyaluronic Acid.

What not to mix with peptides?

For that reason, mixing peptides and glycolic acid is not recommended. Why shouldn't these acids be mixed with peptides? The reason peptides and salicylic acid as well as peptides and glycolic acid aren't efficacious ingredient combinations is because peptides are susceptible to hydrolysis when exposed to acids.

Does hyaluronic acid interact with anything?

How does hyaluronic acid interact with other products? Products that combine hyaluronic acid with other medications or compounds may have some risks of side effects. It's important to tell your healthcare provider about all medications that you're taking, including supplements, vitamins, etc.

What not to pair with niacinamide?

DON'T MIX: AHA/BHA and niacinamide

Niacinamide is used to treat hyperpigmentation and reduce fine lines and wrinkles, while alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants. To understand why niacinamide shouldn't be mixed with AHAs and BHAs, you need to consider pH.

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