Results from a 12-week single-center clinical study in 55 Brazilian females revealed that a novel topical facial serum containing 3% tranexamic acid, 1% kojic acid, and 5% niacinamide was effective in treating mild-to-moderate PIH, with a significant decrease in MI at week 12 compared to baseline and control group.
Tranexamic acid targets uneven skin tone and hyperpigmentation, meaning it's ideal for improving the appearance of acne scars. CAN I USE TRANEXAMIC ACID AND NIACINAMIDE TOGETHER? Yes, it is suitable to layer with Niacinamide and all other ingredients in your AM or PM skincare routine.
Typical Use Level: 1-3%: Tranexamic Acid is typically used at concentrations of 1-3% in skincare formulations. This range is effective in delivering its skin-brightening and anti-pigmentation benefits while maintaining safety and minimizing the risk of irritation.
Oral tranexamic acid treatment benefits maximize after taking it for eight to twelve weeks.
Oral tranexamic acid dosages for hyperpigmentation typically fall on the lower end of the dosage spectrum compared to those given for bleeding disorders. However, within this lower range is a sub-range, normally ranging from 500mg to 1500mg per day.
If you take the wrong dose, Tranexamic Acid Tablets may not work as well and your problem may not improve. Swallow Tranexamic Acid Tablets with a full glass of water, with or without food. Your doctor will tell you how much to take and how long to take the tablets.
Several studies have confirmed the efficacy of topical TXA in treating hyperpigmentation, identifying optimal concentrations between 2% and 5%, with no reported serious adverse effects [8,10,11,12].
Salicylic acid
It is an exfoliating agent that removes dark spots and acne-causing bacteria along with dead skin cells that can lead to pigmentation. However, you need to be patient while using salicylic acid to treat hyperpigmentation.
It can be used alongside other ingredients like niacinamide, hyaluronic acid, retinoids and Vitamin C. What Percentage Of Tranexamic Acid Is Good For Skin? In skincare formulations, we typically see tranexamic acid serums in concentrations ranging from 2% to 5%.
Results: At the end of 8 weeks, MASI, PGA and PtGA showed improvement with both tranexamic acid and vitamin C. However the improvement was more with tranexamic acid than with vitamin C, although not statistically significant.
We recommend applying tranexamic acid once per day when you just start using it, and up to a maximum of two times per day if your skin is tolerating active ingredients well. This is to avoid overloading your skin barrier and potentially causing skin irritation.
The most common potential side effects are listed below. Though reported instances are rare, tranexamic acid can cause allergic reactions, such as itching, swelling, hives, or a rash.
Glycolic Acid
It is an alpha-hydroxy acid (AHA) derived from sugarcane. In low concentrations, glycolic acid produces desquamation of pigmented skin cells. About 30 to 70 per cent of glycolic acid can enhance the penetration of other skin lighteners such as HQ.
One of the newest topical pigment-lightening ingredients in the OTC realm is tranexamic acid.
Are you confused about whether tranexamic acid or azelaic acid is better for dark spots and discoloration? Ultimately, choosing the best of these two acids comes down to personal preference and skin tolerance, because both are relatively gentle options that offer exceptional support for minimizing hyperpigmentation.
HOW LONG DOES TRANEXAMIC AICD TAKE TO WORK ON HYPERPIGMENTATION? Products can take up to six weeks to show full results, due to the time it takes for your skin cells to turnover and the results of any products to reach the surface.
Additionally, a systematic review of three clinical trials found that ginger capsules and myrtle fruit syrup significantly reduced menstrual duration and blood loss compared to a placebo 4. Pomegranate flower capsules were also as good as tranexamic acid at reducing blood loss 4.
Niacinamide is also known for its anti-inflammatory properties which makes it useful for those with acne prone or sensitive skin. Tranexamic acid is more effective for deeper and more stubborn hyperpigmentation such as melasma. Good news though is that Niacinamide and Tranexamic acid can work well together.
Tranexamic acid reduced the amount of blood loss by 40% to 50% for each menstrual cycle [19], translating to an average reduction of 80.32 mL/cycle (95% CI, 32.98-127.67 mL) [5].
Do not chew or break tranexamic acid tablets. Swallow the whole tablet. Tranexamic acid will not stop your period, but it will likely decrease the amount of bleeding by about one-third.
Are there similar medicines to tranexamic acid? There are other medicines that are used to stop bleeding. However, they do not work in the same way as tranexamic acid. Etamsylate can be prescribed for heavy periods, but it may not work as well as tranexamic acid and it's not licensed as a medicine in the UK.