What medication should you avoid after Botox?

Author: Ellen Daniel  |  Last update: Tuesday, November 18, 2025

Are there any Medications I should Stay Away from After Botox? Avoid taking blood thinners for 24 hours before or after your Botox appointment, unless recommended by your doctor. Also avoid taking aspirin or NSAID pain relievers (such as ibuprofen) for 24 hours before or after getting Botox.

What medication can stop Botox from working?

Chloroquine and hydroxychloroquine are two examples of antimalarials within the aminoquinolones group. It is thought that drugs in this group might work to limit BOTOX's ability to reduce your wrinkles by restricting the effect it has on the muscles (which cause the facial wrinkles) it has been injected into.

What medication reacts with Botox?

List of interactions for Botulinum toxin type A
  • Amikacin. Both Botulinum toxin type A and Amikacin have neuromuscular blocking effects.
  • Atracurium. Both Botulinum toxin type A and Atracurium have neuromuscular blocking effects.
  • Cisatracurium. ...
  • Colistimethate. ...
  • Gentamicin. ...
  • Mivacurium. ...
  • Neomycin. ...
  • Netilmicin.

What is not allowed after Botox?

Heavy Lifting: Engaging in heavy weightlifting or strenuous resistance training is not advisable after a Botox treatment. Intense physical exertion can lead to increased blood flow, potentially compromising the precise placement of Botox and impacting the desired cosmetic outcome.

What should I avoid immediately after Botox?

The Top 7 Things Not to Do After Botox®
  • Don't Rub or Touch the Treated Area.
  • Avoid Lying Down for 4–6 Hours.
  • Don't Engage in Intense Exercise.
  • Avoid Alcohol and Certain Medications.
  • Stay Away from Excessive Sun and Heat.
  • Don't Apply Makeup or Skincare Products Immediately.
  • Avoid Facial Treatments for at Least 24–48 Hours.

Dermatologist on what NOT to do after your Botox injections

What can ruin Botox?

7 Things Not to Do After Botox
  • Rubbing Your Face. ...
  • Sun and Heat Exposure. ...
  • Intense Exercise. ...
  • Taking Blood Thinners. ...
  • Alcohol Consumption. ...
  • Washing Your Face With Soap. ...
  • Applying Topical Products.

What products should you avoid after Botox?

After Botox, it's best to avoid skincare products that contain harsh ingredients, such as retinoids, alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), and exfoliating scrubs, for at least 24 to 48 hours. These products can irritate the treated areas and potentially lead to redness or sensitivity.

What medication can you not have Botox with?

Examples of muscle relaxant drugs: Here are some muscle relaxers that may interact with Botox:
  • cyclobenzaprine (Fexmid)
  • metaxalone (Skelaxin)
  • carisoprodol (Soma)
  • tizanidine (Zanaflex)
  • methocarbamol (Robaxin)
  • baclofen (Lioresal)

What cancels out Botox?

This is probably the first question an unhappy patient will ask. Unfortunately, there is no reversal treatment for Botox. Unlike dermal fillers that can be reversed by injecting hyaluronidase, there is no procedure to “undo” Botox.

What can I avoid to make Botox last longer?

Avoid Too Much Sun Exposure

Sun damage can reverse the benefits of Botox by breaking down collagen and causing more lines and wrinkles. The results of Botox can last longer if patients commit to sun protection after treatment. Wear the correct sunscreen and seek shade when possible.

What supplements should you avoid after Botox?

You'll also want to avoid certain vitamins, including fish oil, Ginseng, and Vitamin E. Avoiding these things can minimize any post-Botox bruising. Alcohol— For better Botox results, you'll want your skin to be as healthy and hydrated as possible.

What is the biggest risk of Botox?

Serious adverse effects after cosmetic use of botulinum toxin include dysphagia, muscle weakness, and allergic reactions [22, 23].

What not to do the night before Botox?

Here's what not to do before Botox:
  • Drink Alcohol. Doctors often advise that patients should avoid eating or drinking anything 12 to 24 hours before a surgical procedure. ...
  • Drink Coffee. You should also avoid coffee before Botox. ...
  • Use Topical Products. ...
  • Waxing, Bleaching, or Tweezing. ...
  • Take Aspirin or Blood-Thinning Medications.

What medications cannot mix with Botox?

Interactions with antibiotics, blood thinners, muscle relaxants, sleeping pills, cold or allergy medicine, bronchodilators, and many other prescriptions and over the counter drugs have been reported. These interactions could affect the activity of Botox or the drug it is coadministered with.

What causes Botox to wear off faster?

For those with a faster metabolism, the effects of Botox may wear off more quickly as their bodies metabolize the toxin at an accelerated rate. The process by which the body breaks down and eliminates Botox involves digestive proteins in nerve endings, which can vary between individuals and thus affect Botox longevity.

What is the aftercare for Botox?

To reduce redness, swelling or bruising: Don't rub or put pressure on the treatment area for 12 hours. Stay upright (don't lie down) for three to four hours. Avoid physical exertion for 24 hours.

Can anything mess up Botox?

We advise patients not to lie down, bend over, or exercise for the first four hours after a Botox injection. These activities increase blood flow to the face, which can more or less wash away the Botox before it has fully diffused to the treated areas.

What supplements make Botox last longer?

Take a Zinc Supplement

In a study from the Journal of Drugs in Dermatology, researchers found that people who received Botox and then took a 50-milligram zinc supplement saw a significantly longer duration in their results.

What you Cannot do after Botox?

Top 7 Things Not To Do After Botox
  • Rubbing Your Face. ...
  • Going Under The Sun And Strong Heat. ...
  • 3 . ...
  • Taking Blood Thinners. ...
  • Drinking Alcohol. ...
  • Washing Your Face With Soap. ...
  • Applying Any Topical Products Or Ointments On Your Face Immediately After The Procedure. ...
  • Lying Down On Your Face For The First Few Hours After Treatment.

What stops Botox from working?

BOTOX resistance is a situation in which a patient either has built up antibodies against the botulinum toxin, or happens to metabolize the BOTOX drug exceptionally quickly. As a result, for these patients BOTOX injections provide underwhelming results, a very short-lived effect, or no effect at all.

What is a safer alternative to Botox?

10 BOTOX® Alternatives for Smoother, Firmer Skin
  • Cosmetic Acupuncture. ...
  • Microneedling. ...
  • Chemical Peels. ...
  • Laser Therapy. ...
  • Cryotherapy. ...
  • Facial Creams. ...
  • Neuropeptides. ...
  • Face Patches.

What are the don'ts of Botox?

Don't get a facial or head massage for a full 24 hours after Botox. You should also avoid rubbing your face in the area that was treated.

How to make Botox last longer?

How Can You Make Botox Last Longer?
  1. Be Gentle With Your Face for Two Days. ...
  2. Sleep On Your Back. ...
  3. Exercise the Treated Muscles. ...
  4. Schedule Regular Injection Sessions. ...
  5. Seek Treatment From a Reputable Provider. ...
  6. Don't Exercise Immediately After Treatment. ...
  7. Limit UV Exposure. ...
  8. Get a Good Workout In.

What foods should you avoid when getting Botox?

Foods to Avoid After Botox Treatment
  • Hot peppers – Carolina Reaper, jalapeño, poblano, cayenne, tabasco.
  • Kimchi.
  • Buffalo wings.
  • Curry.
  • Spicy ramen.

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