What is the new treatment for melasma?

Author: Dr. Mossie Mertz DVM  |  Last update: Thursday, July 31, 2025

Topical proton pump inhibitors (PPIs), such as omeprazole, may also inhibit melanogenesis, and present a promising treatment for melasma. Omeprazole topically applied onto the skin of UV-irradiated human subjects elicited significant reduction of pigment levels after 3 weeks compared to untreated controls46.

What is the number one melasma treatment?

Hydroquinone: This is a common treatment for melasma. It is applied to the skin and works to even out the skin tone. Hydroquinone is no longer available in products that you can buy without a prescription.

What gets rid of melasma permanently?

Most cases of melasma will fade away with time and especially with good protection from sunlight and other sources of light. Unfortunately, there is no definitive treatment that will automatically make melasma disappear. At this time there is no way to remove dermal pigment.

What do Koreans do for melasma?

Korean red ginseng powder was well tolerated by most of the patients. In conclusion, Korean red ginseng powder showed good tolerability and beneficial effects in patients with melasma. The use of Korean red ginseng would be counted as a useful adjunctive therapy for patients with melasma.

What is the gold standard treatment for melasma?

Hydroquinone. HQ is the most frequently prescribed depigmenting agent worldwide and it has remained the gold standard for the treatment of melasma, particularly of the epidermal type.

Melasma Causes - How To Treat Pigmentation? | Dr. Danial Ahmed with Dr A.R. Madha

What is the best vitamin to remove melasma?

What other vitamins can treat melasma?
  • Vitamin C (as antioxidants)
  • Vitamin E & fish oil (antioxidants)
  • Green tea (taste good, acts as overall antioxidant for the body & skin)

What is the 3 cream for melasma?

Tri-Luma (fluocinolone/hydroquinone/tretinoin) - Uses, Side Effects, and More. Overview: Tri-Luma is used to treat a condition called melasma, which is where colored areas appear on the face. Tri-Luma contains three medicines.

What is the Chinese treatment for melasma?

Acupuncture is a low-injury non-pharmacological treatment. This study more comprehensively assessed the therapeutic effects of acupuncture on melasma. Acupuncture may be a safe and effective treatment option for melasma. The findings are at some risk of publication and regional bias.

Does anything really work for melasma?

In most patients a combination therapy is needed for treatment for melasma. A common choice is the combination of hydroquinone with a retinoid that increases skin cell turnover and a steroid that decreases skin inflammation.

What is the best cream to remove melasma?

What is the dermatologist-recommended topical melasma treatment?
  • Hydroquinone cream: a topical cream that can be prescribed to help lighten areas of hyperpigmentation.
  • Tretinoin (Retin-A): a topical retinoid for skin lightening.
  • Vitamin-C serum: a powerful antioxidant to address areas of pigmentation.

How did I cured my melasma naturally?

Aloe vera is a fantastic melasma treatment at home, known for its soothing and healing properties. Applying fresh aloe vera gel to affected areas can help reduce pigmentation and improve overall skin health. Leave the gel on for 20-30 minutes before rinsing.

What cancels out melasma?

Prioritizing your skincare routine and using products containing niacinamide, vitamin C and alpha hydroxy acids are essential for helping hyperpigmentation fade over time, celebrity makeup artist, Marco Antonio says. Applying a daily SPF is recommended for preventing and diminishing the appearance of melasma.

What is the root cause of melasma?

Etiologic factors include genetic influences, ultraviolet (UV) radiation, pregnancy, hormonal therapies, cosmetics, phototoxic drugs, and antiseizure medications. Genetic predisposition may be a major factor in the development of melasma. Melasma is more common in females than in males.

What is the fastest way to get rid of melasma?

In-office treatments, such as chemical peels, laser therapy, and Cosmelan peels, and prescription medications, such as Tri-Luma, will be the treatment options that reduce the appearance of melasma the fastest.

Which fruit is good for melasma?

Antioxidants also help repair UV damage that causes melasma. Therefore, eat as many vitamins and antioxidant-rich things as possible, particularly foods high in vitamin C and E like citrus fruits, kiwis, pistachios, almonds, flaxseeds, colorful vegetables and fish (especially salmon).

What pill gets rid of melasma?

Tranexamic acid is a sought out treatment for melasma because of its efficacy and mild side effects. The effectiveness of tranexamic acid has been documented in various journals like Dermatol, J Am Acad dermatol, Dermatol Ther, and Clin Exp dermatol.

What worsens melasma?

"The sun is the major exacerbating factor, whatever the underlying cause." Melasma can be caused or worsened by not only the sun's rays, but also heat and visible light. This means that even sunscreens that protect against skin cancer aren't enough to ward off melasma, says Dr. Kourosh.

What do Koreans use for melasma?

The Korean Melasma Peel introduces a revolutionary approach to skincare by strategically combining Glycolic Acid (GA) and Alpha Hydroxy Acids (AHAs), which is further amplified by the infusion of Oxygen. This results in unparalleled luminosity and rejuvenation.

What is the ultimate remedy for melasma?

Retinol can reduce melasma by inhibiting the activity of melanocytes (the cells responsible for producing melanin). By modulating the skin's response to UV exposure and reducing tyrosinase enzyme activity, retinol helps reduce melasma pigmentation.

What is the permanent cure for melasma?

Most dermatologists start Melasma treatment in India with a topical therapy. The aim of treatment of Melasma on face is to stop the melanocytes from forming any new pigments. Most commonly for the treatment of Melasma on face Hydroquinone is used.

What not to do with melasma?

Avoid the sun between 11 a.m. and 3 p.m., which is the peak time for UV rays. Use only gentle soap or cleanser on your face. Do not rub your face hard. If your doctor prescribes or recommends face creams, use them exactly as directed.

What facial gets rid of melasma?

Treatments For Melasma

These options include laser treatment, chemical peels, dermabrasion and microdermabrasion. These treatments work by stripping away the first few layers of skin and can help lighten the condition's hyperpigmentation in many cases of melasma.

What is the most effective melasma remover?

What is the best melasma medication?
  • Tretinoin. ...
  • Azelaic acid. ...
  • Glycolic acid. ...
  • Thiamidol. ...
  • Tranxanemic acid for melasma. ...
  • Niacinamide. ...
  • Kojic acid. ...
  • Vitamin C. Vitamin C is used for melasma because it is a strong antioxidant with skin-brightening properties.

How much does Tri-Luma cost?

The average cost for 1 tube of 30g of 0.05% of Tri-Luma is $246.00 with a free GoodRx coupon. This is 17.38% off the average retail price of $297.76.

Which serum is best for melasma?

With regular use, arbutin serum helps to even out skin tone, reduce the appearance of pigmentation, & brighten the complexion. By consistently using an arbutin serum as part of your skincare routine, you can achieve a more even, brighter complexion while minimizing the appearance of dark spots & discoloration.

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