What is the best weight loss pill for PCOS?

Author: Mrs. Gladys Gibson III  |  Last update: Saturday, June 21, 2025

Orlistat is as effective as metformin in reducing weight and achieves similar ovulation rates in obese PCOS patients. However, orlistat has minimal side-effects and is better tolerated compared with metformin.

What meds can I take to lose weight with PCOS?

Medications effective for weight loss (in addition to lifestyle modifications) that have been specifically studied in women with PCOS include metformin, acarbose, sibutramine, and orlistat (Xenical). Metformin is probably the first-line medication for obesity or weight reduction in patients with PCOS.

Which is better for PCOS, Wegovy or Ozempic?

As the same drug formulation, they are equally effective for PCOS. “Other drugs like metformin, which is typically prescribed to patients with PCOS, assist with insulin resistance and could be used in conjunction with Wegovy [or] Ozempic for even better results,” Dr. Rowland said.

Can I take phentermine if I have PCOS?

Phentermine-Topiramate: This combination medication is FDA-approved for weight management and can help with appetite control. It may be prescribed to individuals with PCOS who have struggled with overeating and obesity.

Can people with PCOS get Ozempic?

No, Ozempic isn't FDA approved to treat PCOS. But it can be prescribed off-label for PCOS treatment. Some prescribers are using Ozempic off-label to help their patients manage PCOS symptoms.

The Truth About Ozempic for PCOS Weight Loss!

What people should not take phentermine?

Phentermine should not be taken if:
  • You have cardiovascular disease.
  • You are taking or recently stopped taking drugs known as monoamine oxidase inhibitors.
  • You have hyperthyroidism.
  • You have glaucoma.
  • You have a history of drug abuse or agitation.
  • You are pregnant or nursing.

What is the best pill for PCOS?

The easiest way of controlling PCOS is to go on the combined pill (such as Yasmin or Zoely) which prevents recruitment of new egg-follicles and stops the problem from getting worse.

How to get rid of PCOS belly fat?

Consume a high-fibre diet

Studies have found that a high-fibre diet can lead to lower insulin resistance and lower total body fat and belly fat in women with PCOS. You should aim for around 14 grams of fibre per 1000 calories, with women usually recommended to aim for 25 grams daily.

Will insurance pay for Wegovy for PCOS?

Wegovy is the only semaglutide that is FDA approved for treating overweight and obesity, and it may be covered by insurance for individuals with PCOS who meet eligibility requirements, says Dr. Sood. That being said, many insurance plans will not cover weight loss medications, even if you qualify.

What is the Ozempic face?

Ozempic face is a colloquial term, not a medically recognized condition. It describes the facial changes that can accompany rapid weight loss when using medications like Ozempic or another version of the same drug (generic name semaglutide) FDA-approved for weight-loss treatment.

Can I get Mounjaro for PCOS?

Can you get Mounjaro for PCOS? You cannot get Mounjaro for PCOS specifically but you can get it prescribed if you have PCOS and meet the other criteria for taking it. For type 2 diabetes, Mounjaro is only used if other medications like metformin are not working.

How can I speed up weight loss with PCOS?

You can lose weight by exercising regularly and eating a healthy, balanced diet. Your diet should include plenty of fruit and vegetables, (at least 5 portions a day), whole foods (such as wholemeal bread, wholegrain cereals and brown rice), lean meats, fish and chicken.

What are anti obesity drugs for PCOS?

In a 24-week randomised controlled trial in women with PCOS [65], a combination treatment with exenatide (GLP1 mimetic) and metformin was found to be superior to exenatide or metformin monotherapy in reducing weight (mean weight loss of 6 ± 0.5 kg) and improving menstrual cycles, ovulation rate, free androgen index, ...

How much weight can you lose on Ozempic?

Ozempic and similar drugs now yield an average weight loss of 15 to 20 percent, significantly higher than previous options. About one-third experience around 10 percent loss of body weight.

What does a PCOS belly look like?

It's usually large and bloated but can also be small and round, depending on genes and other factors. It involves visceral fat accumulation in the lower abdomen and typically feels hard to touch. A PCOS belly is also characterized by a high waist-to-hip ratio of >0.87 (apple body shape).

Why is my PCOS not losing weight?

It can be hard to lose weight with polycystic ovary syndrome (PCOS) for reasons such as excessive insulin production, excessive hunger, and high blood sugar levels. Researchers estimate anywhere from 38% to 88% of the people with PCOS are overweight or obese.

What is the number one medication for PCOS?

Infertility
  • Femara (letrozole) is commonly used to treat PCOS-related infertility and is now a first-line intervention recommended by the American Society for Reproductive Medicine. ...
  • Clomid (clomiphene citrate) is the most commonly used fertility drug to induce ovulation.

Can Ozempic help with PCOS?

Many people with PCOS have insulin resistance (IR), which is a health issue involving glucose and insulin metabolism. Medications like Ozempic and Mounjaro work effectively to increase insulin sensitivity and production, and can be an excellent tool for those with PCOS.

What is the mini pill for PCOS?

Usually, the combined pill is recommended for managing PCOS symptoms. However, if you cannot tolerate the combined pill or cannot take oestrogen, your doctor may advise taking a mini pill containing desogestrel. This is because desogestrel mini pills have less male hormone effects, which can make PCOS worse..

Which morning drink is best for PCOS?

When it comes to what to drink, one of the best things you can drink for PCOS is green tea. This drink is rich in antioxidants which have anti-carcinogenic and anti-inflammatory effects and can prevent cell damage. Women with PCOS are strictly prohibited from drinking dairy products.

Which is better, Ozempic or phentermine?

Phentermine® may help you lose weight more quickly in the short term, but it's not intended for long-term use. Ozempic®, while slower in weight reduction, offers sustained benefits and is often preferred due to its dual role in managing blood sugar and promoting gradual weight loss.

What is the strongest weight loss prescription pill?

An analysis of 143 studies revealed that phentermine-topiramate and GLP-1 receptor agonists (like liraglutide and semaglutide) are among the most effective medications for reducing weight in people with obesity. The typical body weight reduction with these medications is 6% to 11%.

What organ does phentermine affect?

Rarely, phentermine may cause heart valve disease. Your heart valves open and close like doors as your heart beats to keep your blood flowing in the right direction. Call your healthcare provider right away if you have any of the following symptoms of heart valve disease. Risk of Misuse and Tolerance.

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