1. Wegovy (semaglutide): Approved as a long-term treatment to help with weight loss and maintenance in adults and adolescents 12 years and older with obesity or overweight adults who have at least one weight-related medical condition, such as high cholesterol.
The top prescription weight loss injections include Wegovy, Zepbound, Saxenda, Mounjaro, and Ozempic. Each of these medications has unique benefits and considerations: Wegovy (Semaglutide): Approved by the FDA in 2021, Wegovy is known for helping users lose about 15% of their body weight over 68 weeks.
She mentioned using alternative flours, such as cassava, tapioca, and almond flour, in her meals. Infrared Saunas and Cold Plunges: Clarkson enjoys wellness trends like using infrared saunas and taking cold plunges, which she credits for contributing to her weight loss.
A clinical trial comparing Wegovy vs Mounjaro found that both medications are effective for weight loss and suggests that Mounjaro was more effective.
Wegovy® (semaglutide) Injection 2.4 mg. All doses of Wegovy® are available nationwide.
Average weight loss in a month with Ozempic
This drug is intended for long-term use for Type 2 diabetes, not quick-fix weight loss plans. Results vary, but in one clinical trial that studied 175 patients, the average weight loss was about 15 pounds in three months.
But are these drugs equally effective for weight loss? In a recent study published in JAMA Internal Medicine, researchers compared Ozempic and Mounjaro in real-world conditions and found that people who took Mounjaro lost significantly more weight than those who took Ozempic.
On average, participants taking Wegovy lost more than 2% of their body weight in that time period. So, a person who weighs 200 lbs might expect to lose about 5 lbs in the first month. But for many people, it may take a little more time.
McCarthy lost weight through a combination of a high-protein diet and regular exercise, specifically Piloxing. She also focused on adopting a healthier mindset rather than turning to extreme diets or surgery.
An analysis of 143 studies revealed that phentermine-topiramate and GLP-1 receptor agonists (like liraglutide and semaglutide) are among the most effective medications for reducing weight in people with obesity. The typical body weight reduction with these medications is 6% to 11%.
How did Oprah lose weight? Winfrey has lost her latest weight using a weight-loss drug and with a healthy diet and exercising. She told People the weight-loss medication is just part of her regimen for maintaining a healthy weight. “I know everybody thought I was on it, but I worked so damn hard.
While the $25 Wegovy savings offer is no longer available, there is still a Wegovy Savings Program. However, the details have changed as of January 2025. Depending on your insurance provider and coverage, you may pay as little as $0 per month for Wegovy, up to a maximum of $650 per month.
Ozempic face is a colloquial term, not a medically recognized condition. It describes the facial changes that can accompany rapid weight loss when using medications like Ozempic or another version of the same drug (generic name semaglutide) FDA-approved for weight-loss treatment.
What is similar to Ozempic over-the-counter? Currently, Alli is the only over-the-counter medication FDA-approved to help with weight loss. Other natural substitutes are available for purchase. However, those have not undergone approved testing for safety and weight loss and are not regulated or approved by the FDA.
The drug in Ozempic and Wegovy, semaglutide, is also available in a pill form for Type 2 diabetes called Rybelsus, and doesn't cause as much weight loss.
What insurance covers Wegovy? Several insurance companies, including Blue Cross Blue Shield, Aetna, Cigna, and United Healthcare, typically cover Wegovy in some form or another.
Regular Exercise and Fitness Routines
In addition to her dietary changes, Kelly incorporated regular exercise into her daily routine. Her workout regimen included a mix of cardio, strength training, and flexibility exercises, each of which contributed to her overall fitness and weight loss success.
According to data from randomised controlled trials, Mounjaro supports weight loss of around 4% of body weight after one month. After two months, it's around 6% of body weight.
MOUNJARO is contraindicated in patients with a personal or family history of MTC or in patients with MEN 2. Counsel patients regarding the potential risk for MTC with the use of MOUNJARO and inform them of symptoms of thyroid tumors (e.g., a mass in the neck, dysphagia, dyspnea, persistent hoarseness).
How fast you can lose 20 lbs on semaglutide (Wegovy) depends on your starting weight and other factors. If you weigh 232 lbs at the start of Wegovy treatment, you can expect to lose 20 lbs in around 16-20 weeks (4-5 months).
Some people who use semaglutide (Ozempic, others) have noted sagging skin in the buttocks, calling it “Ozempic butt.” While lifestyle modifications may help prevent this weight loss side effect, a doctor may recommend surgery to treat excess, sagging skin.