Ozempic acts like a hormone your body makes. Mounjaro works similarly, but it acts like two hormones instead of one. Compared to Ozempic, Mounjaro might work even better for weight loss. One study showed that a 15 milligram-dose of this drug taken every week led people to lose more than 20% of their body weight.
Mounjaro is more effective for weight loss than Ozempic.
While Mounjaro is known for effectively reducing A1C levels and weight, Ozempic also addresses cardiovascular risks associated with Type 2 diabetes. Several studies have shown that Mounjaro is more effective than Ozempic for blood sugar control and weight loss.
Both Wegovy and Ozempic contain semaglutide, but Wegovy is prescribed for long-term weight management, while Ozempic is used to control blood sugar levels in type 2 diabetes and help protect kidney function.
Regular Exercise and Fitness Routines
In addition to her dietary changes, Kelly incorporated regular exercise into her daily routine. Her workout regimen included a mix of cardio, strength training, and flexibility exercises, each of which contributed to her overall fitness and weight loss success.
"Within about two weeks, I had already lost a few pounds," Schorr said. "Everyone was like, 'Oh, you already are looking like you're losing weight in just the first few days. '" Schorr said she lost 50 pounds over the course of 11 months.
Which is better for weight loss: Mounjaro or Zepbound? Neither is "better" as they contain the identical active ingredient (tirzepatide) and work exactly the same way in the body.
You can expect to lose 6% of your body weight after two months, 9% after three months, and 11% after four months. But by the 18-month mark, Mounjaro patients experience around 21% weight loss. But be prepared - you'll need to incorporate healthier habits into your lifestyle for the weight to stay off in the long term.
Ozempic face is a colloquial term, not a medically recognized condition. It describes the facial changes that can accompany rapid weight loss when using medications like Ozempic or another version of the same drug (generic name semaglutide) FDA-approved for weight-loss treatment.
What's the most effective weight loss medication? GLP-1 agonists are the most effective medications for weight loss. Current GLP-1 agonists approved for weight loss include Wegovy, Zepbound and Saxenda. Other medications, such as Ozempic, may be prescribed for weight loss although that's not the intended use.
After taking Ozempic® for six weeks
By this point, you'll have started the 0.5 mg dose and will likely be seeing some changes. In the same two trials mentioned above, between weeks four and eight at 0.5 mg there was an average weight reduction of around 2%, meaning that by week eight the total loss was about 4%.
If you're having trouble accessing Ozempic, your healthcare team may recommend an alternative that works in a similar way. For Type 2 diabetes, this may include Rybelsus, Trulicity, or Mounjaro. If you're taking Ozempic off-label for weight loss, Wegovy, Zepbound, and Saxenda are three FDA-approved options.
New prescription weight loss drugs like Ozempic, Wegovy and Zepbound are currently in the spotlight for their fast, dramatic results. Indeed, these medications are helping people lose a lot of weight. Plus, they're enjoying a better quality of life and can do more with greater confidence.
Yes, it is possible for a person to lose 20 lbs in 3 months with a healthy diet, regular exercise, and a sustainable calorie deficit. However, experts recommend a gradual weight loss of 1 to 2 pounds per week to avoid health risks.
How much weight is lost on Zepbound? Patients on Zepbound (tirzepatide) 5mg weekly lost 16.1 kg (35.5 lb) on average after 72 weeks. For Zepbound's 10mg weekly dose, the average weight loss was 22.2 kg (48.9 lb), and for Zepbound's 15mg weekly dose average weight loss was 23.6 kg (52.0 lb) over 72 weeks.
In general, the longer-acting GLP-1 agonists which are injected weekly, such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), are associated with greater weight loss than the shorter-acting GLP-1 agonists such as liraglutide (Saxenda).
Retail prices for Zepbound and Mounjaro differ based on dosage and quantity. The average retail costs of both medications can reach around $1,000 per month. Costs can change based on the pharmacy where the medication is purchased.
Ozempic has not been directly compared with Wegovy for helping weight loss. But based on a review of studies, Wegovy may lead to more weight loss than Ozempic. This is likely because doctors typically prescribe Wegovy at a higher maintenance (long-term) dosage than Ozempic.
The reasons why you're not losing weight on Mounjaro might be that you're not eating in a calorie deficit, you've hit a temporary weight-loss plateau, or the current dose that you're on isn't high enough to lower your hunger to the point where you're eating less.
How fast you can lose 20 lbs on semaglutide (Wegovy) depends on your starting weight and other factors. If you weigh 232 lbs at the start of Wegovy treatment, you can expect to lose 20 lbs in around 16-20 weeks (4-5 months).
Hormonal imbalances and underlying conditions
If there is any type of hormonal imbalance in your body, it could affect your weight loss results—even if you're on Zepbound. For example, people with type 2 diabetes can still lose weight on Zepbound, just not as much as those without diabetes.
How Much Weight Can You Expect to Lose on Ozempic? A large clinical trial from 2021 found that people with obesity who took semaglutide at a dose of 2.4 mg and engaged in lifestyle interventions lost 14.9% of their body weight after 68 weeks. On average, participants lost 34 pounds during the trial.