Mixing the toxin with too much saline increases the risk of complications because a dilute solution is more likely to migrate into other muscle areas, he says, causing problems like a droopy eyelid, double vision or a droopy lip. And a watered-down injection isn't as likely to hold up.
The recommended dose is 100 Units of BOTOX, and is the maximum recommended dose. The recommended dilution is 100 Units/10 mL with preservative-free 0.9% Sodium Chloride Injection, USP (see Table 1).
Botox must be injected into the superficial layers of the skin in some areas, while in others, it needs to be injected deeply. One example is the masseter muscle near the mouth. If a practitioner doesn't inject this muscle deeply enough, patients can end up with an uneven or unbalanced smile.
This watering down of the solution renders the injection much less effective, meaning it will only last a few weeks rather than the full three to four months expected of the high-quality product.
I also know my standard dilution of 2 ml would require 1 ml for 50 units. 2-1=1. I would first draw up 1 ml NaCl then add another 1 ml of my standard Botox solution.
While there is a common perception that Botox® can be “watered” down, this is highly unlikely. More likely is that you did not receive enough units to tackle your areas of concern, or the Botox® was placed in less than ideal areas.
Botox is measured in “units.” There are 100 units in one syringe of Botox.
The manufacturer recommends that Botox be reconstituted in unpreserved saline and used within 5 hours of dilution, after which it should be disposed of.
Stress releases cortisol, the “stress hormone,” which triggers an inflammatory response within the body. Consistently high-stress levels can cause the body to break down Botox more quickly while speeding the aging process.
Answer: Botox takes a while to work
Once the muscles stop contracting, the lines can take quite a while to disappear in some patients. If you continue to maintain the inability of the muscles to contract by having repeat Botox before the muscle wakes up ( around 3 to 4 months), the lines should continue to improve.
However, when it is not performed properly, Botox can result in a "frozen" or fake look. The most common causes of botched Botox are: Improper injection techniques. Many unskilled injectors make the mistake of injecting Botox too deeply or too superficially into the skin.
The most common reason that Botox does not work is that not enough was given. Botox is not a one size fits all treatment and the same dosage does not work for everyone. Some individuals may need additional Botox to reach an effective level of muscle weakness. The Botox may also be old, overdiluted, or fake.
The ratio: 1 ml of preserved saline : to one vial of Dysport (300 units) OR. 1 ml of preserved saline : to one vial of Botox (100 units)
The recommended dose is 200 Units of BOTOX per treatment, and should not be exceeded. Reconstitute a 200 Unit vial of BOTOX with 6 mL of 0.9% non-preserved saline solution and mix the vial gently.
Using an appropriate-sized needle and syringe, draw up 1.25 mL or 2.5 mL of 0.9% nonpreserved sterile saline (see dilution table). Disconnect the syringe from the needle, then gently mix BOTOX® Cosmetic with the saline by rotating the vial.
Too much Botox in the forehead muscles can cause the eyebrows to droop, making the upper eyelids look very heavy and hooded. The face may look angry or sad all the time. Too much Botox around the eyes can dramatically affect facial expression. The face is simply frozen.
Answer: Will Massage Make Botox Go Away Quicker? I'm very sorry you are experiencing unfavorable reactions to your Botox treatment. The unfortunate news is massaging will not change the longevity of the Botox; however the good news is the effects should soften soon.
Again, if this is still an issue after about a week to ten days after your Botox treatment, go back to your provider. It's a very easy fix to put a little bit extra Botox in your strong side, and that will make everything nice and even. “Why is my Botox uneven?”
Botox can be kept in a medical fridge for up to four weeks whilst retaining its potency, so long as the correct storage requirements are met. In order for Botox to remain safe for administration, it must be stored between a specific temperature range, and that is why a dedicated medical fridge must be used.
Answer: Botox looks like a very fine powder
It is present in such small quantities that you can barely see it and looks like a dusting of talcum powder on the bottom of the vial.
Why does Botox eventually stop working? Your body makes new neurotransmitters all the time, so the “blocking” effect of Botox gradually wears off as these chemicals start circulating in your body again. The muscles are no longer inhibited.
Between 10 to 50 Units of botox
A forehead botox injection can require between 10 to 50 units needed in the forehead depending on the severity of your wrinkles. Allergan, the manufacturer of Botox suggests the amount of units that's recommended in the “five” sites of the forehead is 4 units.
Some practitioners say they inject an average of 10 to 30 units into the forehead. Allergan, the manufacturer of Botox Cosmetic, suggests a dosage of 4 units each in five sites on the forehead, totaling 20 units. Your practitioner may start out with a low-unit dosage in each injection at first.
You should NEVER leave a tip for your PA/NP or nurse injector. Injectables are medications, just like a blood pressure pill or a thyroid medication. You would not tip your primary care provider for doing an EKG on you so no need to tip on our medical services either.