What are the facial signs of B12 deficiency?

Author: Graciela Crooks DDS  |  Last update: Sunday, August 31, 2025

The deficiency of vitamin B12 can cause specific skin manifestations, such as hyperpigmentation, vitiligo, angular stomatitis, and hair and nail changes [1].

What are the worst symptoms of B12 deficiency?

Symptoms of vitamin B12 deficiency
  • mouth ulcers.
  • pins and needles (paraesthesia)
  • changes in the way that you walk and move around.
  • disturbed vision.
  • irritability.
  • depression.
  • changes in the way you think, feel and behave.
  • a decline in your mental abilities, such as memory, understanding and judgement (dementia)

Can B12 deficiency cause face changes?

Skin lesions associated with vitamin B12 deficiency are skin hyperpigmentation, vitiligo, angular stomatitis, and hair changes. Cutaneous lesions that do not respond to conventional therapy can be an indication of vitamin B12 deficiency. Malabsorption is the most common cause of vitamin B12 deficiency.

What are the signs of B12 deficiency around the eyes?

Yellow tinge eyes

People dealing with issues of vitamin B12 often look pale and have a slight yellow tinge to the skin and in the white area of the eyes which is a condition known as jaundice. This happens as the body stops producing enough red blood cells due to a lack of B12 vitamin.

What are the weird sensations of B12 deficiency?

Vitamin B12deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet. difficulty walking (staggering, balance problems) anemia.

The 1st Sign of a Methylcobalamin (B12) Deficiency

What medications should not be taken with B12?

Possible interactions include:
  • Aminosalicylic acid (Paser). Taking this drug used to treat digestive problems might reduce your body's ability to absorb vitamin B-12.
  • Colchicine (Colcrys, Mitigare, Gloperba). ...
  • Metformin (Glumetza, Fortamet, others). ...
  • Proton pump inhibitors. ...
  • Vitamin C (ascorbic acid) supplements.

What organ is affected by B12 deficiency?

If vitamin B12 deficiency is left untreated, it can cause lasting side effects that affect the nervous system and brain. More severe side effects of vitamin B12 deficiency include: Peripheral neuropathy. Degeneration of the spinal cord.

What are the 4 stages of B12 deficiency?

Vitamin B12 Deficiency: Stages, Causes, Symptoms, and Treatment
  • Stage 1: Early Serum Depletion.
  • Stage 2: Cellular Depletion.
  • Stage 3: Damaged Metabolism.
  • Stage 4: Clinical Damage.

What blocks B12 absorption?

Conditions affecting the stomach

Some stomach conditions or stomach operations can prevent the absorption of enough vitamin B12. For example, a gastrectomy, a surgical procedure where part of your stomach is removed, increases your risk of developing a vitamin B12 deficiency.

What is the fastest way to fix B12 deficiency?

Vitamin B12 deficiency anaemia is usually treated with injections of vitamin B12, called hydroxocobalamin. At first, you'll have these injections every other day for 2 weeks or until your symptoms have started improving.

What does a vitamin deficiency do to your face?

However, if you're deficient in certain vitamins, changes on your skin can be a tell-tale sign. Insufficient levels of Vitamin A and E can lead to acne formation on your face, whereas low levels of Vitamin B12 deficiency can make your skin look paler than ever.

What happens to your body when your B12 is extremely low?

Key points about vitamin B12 deficiency anemia

Without enough red blood cells, your tissues and organs don't get enough oxygen. Without enough oxygen, your body can't work as well. Symptoms include weak muscles, numbness, trouble walking, nausea, weight loss, irritability, fatigue, and increased heart rate.

What does B12 acne look like?

High-dose vitamins B6 and B12 have also been linked to rosacea fulminans, a condition that looks like acne. Rosacea is marked by large red bumps and pustules that typically appear on the nose, chin, and/or cheeks.

What are the mental symptoms of low B12?

psychological problems, which can range from mild depression or anxiety, to confusion and dementia. problems with balance and coordination. pins and needles. incontinence.

What foods should be avoided if you have B12 deficiency?

Avoid foods rich in fiber

Foods high in fiber, particularly soluble fiber, can interfere with the absorption of B12. Fiber binds with B12 and prevents its absorption in the small intestine.

What cancers are linked to B12 deficiency?

Particularly, individuals with lung, stomach, colon, oesophageal, and pancreatic cancers are more prone to experiencing a deficiency in vitamin B12. This article will discuss different types of cancers causing vitamin B12 deficiency, associated symptoms, and available treatment options.

Can lack of B12 affect your eyes?

Optic neuropathy is reported to occur in less than 1% of VitB12 deficient patients. It mostly results in progressive, bilateral, painless loss of vision associated with abnormal color vision and central or ceco – central scotomas.

Which fruit is rich in vitamin B12?

There are ten major sources of vitamin B12 fruits. These are apples, bananas, oranges, mangoes, strawberries, guava, avocado, pomegranate, kiwi, and blueberries. Apples- Apples rank first in the vitamin B12 fruits list.

What does B12 fatigue feel like?

Weakness. Your muscles may lack strength. You also might feel tired or lightheaded. Your doctor can check how much B12 is in your body, but not all of it may be useable.

What cancels out B12?

Summary: As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).

When should I take B12, morning or night?

It's advised to take vitamin b12 supplements in the morning for better energy and absorption. Those at higher risk of deficiency include people with plant-based diets, older adults, and individuals with certain medical conditions or surgeries.

Should seniors take B12 or B complex?

If you are an older adult, you should be taking a supplement for B12 as well as trying to incorporate B12 into your diet. It is vital for good health and cognitive functioning. Studies continue to show all the ways it is beneficial for your overall health.

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